Inseparable tandem: evolution chooses ATP and Ca2+to control life, death and cellular signalling

Signalling at membrane contact sites: two membranes come together to handle second messengers

(2016) Tim P Levine et al.   CURRENT OPINION IN CELL BIOLOGY

Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion

(2016) A. Verkhratsky et al.   EMBO JOURNAL

Divalent Metal Ions Mg2+ and Ca2+ Have Distinct Effects on Protein Kinase A Activity and Regulation

(2015) Matthias J. Knape et al.   ACS Chemical Biology

Birth of the eukaryotes by a set of reactive innovations: New insights force us to relinquish gradual models

(2015) Dave Speijer   BIOESSAYS

Signalling in ciliates: long- and short-range signals and molecular determinants for cellular dynamics

(2015) Helmut Plattner   BIOLOGICAL REVIEWS

Organellar channels and transporters

(2015) Haoxing Xu et al.   CELL CALCIUM

The evolution of bacterial mechanosensitive channels

(2015) Ian R. Booth et al.   CELL CALCIUM

Calcium signalling in the ciliated protozoan model, Paramecium: Strict signal localisation by epigenetically controlled positioning of different Ca2+-channels

(2015) Helmut Plattner   CELL CALCIUM

Evolution of calcium signalling

(2015) Helmut Plattner et al.   CELL CALCIUM

Insights into the early evolution of animal calcium signaling machinery: A unicellular point of view

(2015) Xinjiang Cai et al.   CELL CALCIUM

Molecular aspects of calcium signalling at the crossroads of unikont and bikont eukaryote evolution – The ciliated protozoan Paramecium in focus

(2015) Helmut Plattner   CELL CALCIUM

The calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium spp

(2015) Sebastian Lourido et al.   CELL CALCIUM

The impact of mitochondrial endosymbiosis on the evolution of calcium signaling

(2015) Neil W. Blackstone   CELL CALCIUM

Increasing complexity and versatility: How the calcium signaling toolkit was shaped during plant land colonization

(2015) Kai H. Edel et al.   CELL CALCIUM

A primer of NAADP-mediated Ca2+ signalling: From sea urchin eggs to mammalian cells

(2015) Antony Galione   CELL CALCIUM

Coupling acidic organelles with the ER through Ca2+ microdomains at membrane contact sites

(2015) Christopher J. Penny et al.   CELL CALCIUM

Molecular diversity and pleiotropic role of the mitochondrial calcium uniporter

(2015) Marta Murgia et al.   CELL CALCIUM

Evolution of acidic Ca2+ stores and their resident Ca2+-permeable channels

(2015) Sandip Patel et al.   CELL CALCIUM

Calcium signaling in trypanosomatid parasites

(2015) Roberto Docampo et al.   CELL CALCIUM

The ancient roots of calcium signalling evolutionary tree

(2015) Helmut Plattner et al.   CELL CALCIUM

Inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum: A single-channel point of view

(2015) Don-On Daniel Mak et al.   CELL CALCIUM

Steep Rock Lake: Sedimentology and geochemistry of an Archean carbonate platform

(2015) Philip Fralick et al.   EARTH-SCIENCE REVIEWS

Cellular functions of Rab GTPases at a glance

(2015) Y. Zhen et al.   JOURNAL OF CELL SCIENCE

A Transient Receptor Potential Ion Channel inChlamydomonasShares Key Features with Sensory Transduction-Associated TRP Channels in Mammals

(2015) Luis Arias-Darraz et al.   PLANT CELL

Theory for rates, equilibrium constants, and Brønsted slopes in F1-ATPase single molecule imaging experiments

(2015) Sándor Volkán-Kacsó et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular expression of purinoceptors

(2015) Geoffrey Burnstock   Purinergic Signalling

Function and dysfunction of two-pore channels

(2015) Sandip Patel   Science Signaling

Function and dysfunction of two-pore channels

(2015) Sandip Patel   Science Signaling

The Principle of Membrane Fusion in the Cell (Nobel Lecture)

(2014) James Edward Rothman   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Molecular Machinery of Neurotransmitter Release (Nobel Lecture)

(2014) Thomas C. Südhof   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biology of purinergic signalling: Its ancient evolutionary roots, its omnipresence and its multiple functional significance

(2014) Alexei Verkhratsky et al.   BIOESSAYS

MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter

(2014) K. J. Kamer et al.   EMBO REPORTS

Mg2+ coordinating dynamics in Mg:ATP fueled motor proteins

(2014) A. Bojovschi et al.   JOURNAL OF CHEMICAL PHYSICS

Role of PKD2 in Rheotaxis in Dictyostelium

(2014) Wanessa C. Lima et al.   PLoS One

Purinergic signalling and immune cells

(2014) Geoffrey Burnstock et al.   Purinergic Signalling

Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels

(2014) T. Rahman et al.   Science Signaling

Effect of Calcium on the Oxidative Phosphorylation Cascade in Skeletal Muscle Mitochondria

(2013) Brian Glancy et al.   BIOCHEMISTRY

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

Calcium in the Early Evolution of Living Systems: A Biohistorical Approach

(2013) Jozef Kazmierczak et al.   CURRENT ORGANIC CHEMISTRY

Intracellular calcium channels in protozoa

(2013) Roberto Docampo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hydrothermal modification of the Sikhote-Alin iron meteorite under low pH geothermal environments. A plausibly prebiotic route to activated phosphorus on the early Earth

(2013) David E. Bryant et al.   GEOCHIMICA ET COSMOCHIMICA ACTA

Functional Properties of FiveDictyostelium discoideumP2X Receptors

(2013) Abigail Baines et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+ signalling early in evolution - all but primitive

(2013) H. Plattner et al.   JOURNAL OF CELL SCIENCE

Calcium Regulation in the Protozoan Model,Paramecium tetraurelia

(2013) Helmut Plattner   JOURNAL OF EUKARYOTIC MICROBIOLOGY

A Database of Alkaline-Earth-Coordinated Peptide Cross Sections: Insight into General Aspects of Structure

(2013) Jonathan M. Dilger et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Mg2+ ions affect structure of central domain of 18S rRNA near ribosomal protein S13 binding site

(2013) A. V. Ivanov et al.   MOLECULAR BIOLOGY

Genome-Wide Analysis of the Phosphoinositide Kinome from Two Ciliates Reveals Novel Evolutionary Links for Phosphoinositide Kinases in Eukaryotic Cells

(2013) George Leondaritis et al.   PLoS One

Purinergic signalling in the urinary tract in health and disease

(2013) Geoffrey Burnstock   Purinergic Signalling

Purinergic signalling in endocrine organs

(2013) Geoffrey Burnstock   Purinergic Signalling

Characterization of new G protein-coupled adenine receptors in mouse and hamster

(2013) Dominik Thimm et al.   Purinergic Signalling

Purinergic signalling in the kidney in health and disease

(2013) Geoffrey Burnstock et al.   Purinergic Signalling

EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex

(2013) Y. Sancak et al.   SCIENCE

Primitive ATP-activated P2X receptors: discovery, function and pharmacology

(2013) Samuel J. Fountain   Frontiers in Cellular Neuroscience

Evolution of the Animal Apoptosis Network

(2013) C. M. Zmasek et al.   Cold Spring Harbor Perspectives in Biology

FUSE: a profit maximization approach for functional summarization of biological networks

(2012) Boon-Siew Seah et al.   BMC BIOINFORMATICS

The Rabs: A family at the root of metazoan evolution

(2012) Harald Stenmark   BMC BIOLOGY

Calcium signaling in closely related protozoan groups (Alveolata): Non-parasitic ciliates (Paramecium, Tetrahymena) vs. parasitic Apicomplexa (Plasmodium, Toxoplasma)

(2012) H. Plattner et al.   CELL CALCIUM

Intracellular P2X receptors as novel calcium release channels and modulators of osmoregulation inDictyostelium

(2012) Venketesh Sivaramakrishnan et al.   Channels

Cyclic ADP-ribose and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) as Messengers for Calcium Mobilization

(2012) Hon Cheung Lee   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct mobilisation of lysosomal Ca 2+ triggers complex Ca 2+ signals

(2012) Bethan S. Kilpatrick et al.   JOURNAL OF CELL SCIENCE

Pannexin 1 forms an anion-selective channel

(2012) Weihong Ma et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Cellular function and molecular structure of ecto-nucleotidases

(2012) Herbert Zimmermann et al.   Purinergic Signalling

Linking NAADP to Ion Channel Activity: A Unifying Hypothesis

(2012) A. H. Guse   Science Signaling

Adenosine and ATP Receptors in the Brain

(2011) Geoffrey Burnstock et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Calcium-Release Channels in Paramecium. Genomic Expansion, Differential Positioning and Partial Transcriptional Elimination

(2011) Eva-Maria Ladenburger et al.   PLoS One

Identification of Intracellular and Plasma Membrane Calcium Channel Homologues in Pathogenic Parasites

(2011) David L. Prole et al.   PLoS One

Mammalian apoptosis in a parasitic worm

(2011) S. H. Rosenberg   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonsynaptic and nonvesicular ATP release from neurons and relevance to neuron–glia signaling

(2011) R. Douglas Fields   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The transient receptor potential family of ion channels

(2011) Bernd Nilius et al.   GENOME BIOLOGY

Evolution of neuronal signalling: Transmitters and receptors

(2010) Charles H.V. Hoyle   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Ionotropic receptors in neuronal–astroglial signalling: What is the role of “excitable” molecules in non-excitable cells

(2010) Ulyana Lalo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression

(2010) Smitha Sreedharan et al.   BMC GENOMICS

Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes

(2010) Oleg Palygin et al.   CELL CALCIUM

Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signals

(2010) Sandip Patel et al.   CELL CALCIUM

Cell biology of Ca2+-triggered exocytosis

(2010) Zhiping P Pang et al.   CURRENT OPINION IN CELL BIOLOGY

Protein Phosphatase 2B (PP2B, Calcineurin) in Paramecium: Partial Characterization Reveals That Two Members of the Unusually Large Catalytic Subunit Family Have Distinct Roles in Calcium-Dependent Processes

(2010) D. Fraga et al.   EUKARYOTIC CELL

Neuroglial ATP release through innexin channels controls microglial cell movement to a nerve injury

(2010) Stuart E. Samuels et al.   JOURNAL OF GENERAL PHYSIOLOGY

Identification and characterization of a novel bacterial ATP-sensitive K+ channel

(2010) Seung Bum Choi et al.   JOURNAL OF MICROBIOLOGY

Evolution of acidocalcisomes and their role in polyphosphate storage and osmoregulation in eukaryotic microbes

(2010) R. Docampo et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The synapsins: Key actors of synapse function and plasticity

(2010) F. Cesca et al.   PROGRESS IN NEUROBIOLOGY

Crystal Structure of a Legionella pneumophila Ecto -Triphosphate Diphosphohydrolase, A Structural and Functional Homolog of the Eukaryotic NTPDases

(2010) Julian P. Vivian et al.   STRUCTURE

Cell Death Mechanisms and Their Implications in Toxicology

(2010) Sten Orrenius et al.   TOXICOLOGICAL SCIENCES

Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling

(2010) Sandip Patel et al.   TRENDS IN CELL BIOLOGY

Cytosolic Ca2+ Buffers

(2010) B. Schwaller   Cold Spring Harbor Perspectives in Biology

The Role of Transient Receptor Potential Cation Channels in Ca2+ Signaling

(2010) M. Gees et al.   Cold Spring Harbor Perspectives in Biology

Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death

(2010) G Burnstock et al.   Cell Death & Disease

Modeling Mitochondrial Bioenergetics with Integrated Volume Dynamics

(2010) Jason N. Bazil et al.   PLoS Computational Biology

Evolutionary origins of the purinergic signalling system

(2009) G. Burnstock et al.   Acta Physiologica

Calcium signaling via two-pore channels: local or global, that is the question

(2009) Michael X. Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The role of Ca2+ signaling in the coordination of mitochondrial ATP production with cardiac work

(2009) Robert S. Balaban   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Regulation of mitochondrial dehydrogenases by calcium ions

(2009) Richard M. Denton   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Ca2+ transfer from the ER to mitochondria: When, how and why

(2009) Rosario Rizzuto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A P2X receptor from the tardigrade species Hypsibius dujardini with fast kinetics and sensitivity to zinc and copper

(2009) Selvan Bavan et al.   BMC EVOLUTIONARY BIOLOGY

Exocytosis of Post-Golgi Vesicles Is Regulated by Components of the Endocytic Machinery

(2009) Jyoti K. Jaiswal et al.   CELL

First and last ancestors: reconstructing evolution of the endomembrane system with ESCRTs, vesicle coat proteins, and nuclear pore complexes

(2009) Mark C Field et al.   CURRENT OPINION IN CELL BIOLOGY

Secretory granules in inositol 1,4,5-trisphosphate-dependent Ca2+ signaling in the cytoplasm of neuroendocrine cells

(2009) Seung Hyun Yoo   FASEB JOURNAL

Concept of Sustained Ordering and an ATP-related Mechanism of Life’s Origin

(2009) Erik Galimov   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ATP Regulates Calcium Efflux and Growth in E. coli

(2009) Riffat Naseem et al.   JOURNAL OF MOLECULAR BIOLOGY

The role of ATP-binding cassette (ABC) proteins in protozoan parasites

(2009) Virginie Sauvage et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Purinoceptors on Neuroglia

(2009) Alexei Verkhrasky et al.   MOLECULAR NEUROBIOLOGY

NAADP mobilizes calcium from acidic organelles through two-pore channels

(2009) Peter J. Calcraft et al.   NATURE

The use of yeast to understand TRP-channel mechanosensitivity

(2009) Zhenwei Su et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Signaling at Purinergic P2X Receptors

(2008) Annmarie Surprenant et al.   Annual Review of Physiology

Rapid downregulation of the Ca2+-signal after exocytosis stimulation in Paramecium cells: Essential role of a centrin-rich filamentous cortical network, the infraciliary lattice

(2008) Ivonne M. Sehring et al.   CELL CALCIUM

Effects of extracellular ATP on the physiology ofStreptomyces coelicolorA3(2)

(2008) Ming Li et al.   FEMS MICROBIOLOGY LETTERS

Permeation Properties of a P2X Receptor in the Green AlgaeOstreococcus tauri

(2008) Samuel J. Fountain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SNAREing the Basis of Multicellularity: Consequences of Protein Family Expansion during Evolution

(2008) T. H. Kloepper et al.   MOLECULAR BIOLOGY AND EVOLUTION

Unicellular Ca2+ Signaling 'Toolkit' at the Origin of Metazoa

(2008) X. Cai   MOLECULAR BIOLOGY AND EVOLUTION

Calcium efflux is essential for bacterial survival in the eukaryotic host

(2008) Jason W. Rosch et al.   MOLECULAR MICROBIOLOGY

P2X receptors and synaptic plasticity

(2008) Y. Pankratov et al.   NEUROSCIENCE

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS

Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer

(2008) H. Y. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a vesicular nucleotide transporter

(2008) K. Sawada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAADP: A Universal Ca2+ Trigger

(2008) A. H. Guse et al.   Science Signaling

Ca2+ signalling in plants and green algae – changing channels

(2008) Glen L. Wheeler et al.   TRENDS IN PLANT SCIENCE