Sex in a test tube: testing the benefits ofin vitrorecombination

Sex speeds adaptation by altering the dynamics of molecular evolution

(2016) Michael J. McDonald et al.   NATURE

Lineage Tracking for Probing Heritable Phenotypes at Single-Cell Resolution

(2016) Denis Cottinet et al.   PLoS One

Freeze–thaw cycles as drivers of complex ribozyme assembly

(2015) Hannes Mutschler et al.   Nature Chemistry

Methods for the directed evolution of proteins

(2015) Michael S. Packer et al.   NATURE REVIEWS GENETICS

A tortoise–hare pattern seen in adapting structured and unstructured populations suggests a rugged fitness landscape in bacteria

(2015) Joshua R. Nahum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stepwise error-prone PCR and DNA shuffling changed the pH activity range and product specificity of the cyclodextrin glucanotransferase from an alkaliphilicBacillus sp

(2015) Susanne Melzer et al.   FEBS Open Bio

Viewing Protein Fitness Landscapes Through a Next-Gen Lens

(2014) J. I. Boucher et al.   GENETICS

Empirical fitness landscapes and the predictability of evolution

(2014) J. Arjan G.M. de Visser et al.   NATURE REVIEWS GENETICS

In Vivo Evolution of a Catalytic RNA Couples Trans-Splicing to Translation

(2014) Karen E. Olson et al.   PLoS One

Multidimensional Epistasis and the Transitory Advantage of Sex

(2014) Stefan Nowak et al.   PLoS Computational Biology

Recycling of Informational Units Leads to Selection of Replicators in a Prebiotic Soup

(2013) Nilesh Vaidya et al.   CHEMISTRY & BIOLOGY

To get what we aim for - progress in diversity generation methods

(2013) Anna J. Ruff et al.   FEBS Journal

Comprehensive experimental fitness landscape and evolutionary network for small RNA

(2013) J. I. Jimenez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic shuffling and in vitro selection reveal the rugged adaptive fitness landscape of a kinase ribozyme

(2013) E. A. Curtis et al.   RNA

Spontaneous network formation among cooperative RNA replicators

(2012) Nilesh Vaidya et al.   NATURE

Quantifying the Adaptive Potential of an Antibiotic Resistance Enzyme

(2012) Martijn F. Schenk et al.   PLoS Genetics

The low cost of recombination in creating novel phenotypes

(2011) Andreas Wagner   BIOESSAYS

Ribozyme-Catalyzed Transcription of an Active Ribozyme

(2011) A. Wochner et al.   SCIENCE

Initial Mutations Direct Alternative Pathways of Protein Evolution

(2011) Merijn L. M. Salverda et al.   PLoS Genetics

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Complexity through Recombination: From Chemistry to Biology

(2010) Niles Lehman et al.   Entropy

GENOME STRUCTURE AND THE BENEFIT OF SEX

(2010) Richard A. Watson et al.   EVOLUTION

Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes

(2010) Frank J. Poelwijk et al.   JOURNAL OF THEORETICAL BIOLOGY

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

(2010) J. J. Agresti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Evolutionary Enigma of Sex

(2009) Sarah P. Otto   AMERICAN NATURALIST

Exploring the Effect of Sex on Empirical Fitness Landscapes

(2009) J. Arjan G. M. de Visser et al.   AMERICAN NATURALIST

Non-Enzymatic Template-Directed Recombination of RNAs

(2009) Sergey Nechaev et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploring protein fitness landscapes by directed evolution

(2009) Philip A. Romero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Competition between recombination and epistasis can cause a transition from allele to genotype selection

(2009) R. A. Neher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The dawn of the RNA World: Toward functional complexity through ligation of random RNA oligomers

(2009) C. Briones et al.   RNA

From fitness landscapes to seascapes: non-equilibrium dynamics of selection and adaptation

(2009) Ville Mustonen et al.   TRENDS IN GENETICS

A Recombination-Based Model for the Origin and Early Evolution of Genetic Information

(2008) Niles Lehman   CHEMISTRY & BIODIVERSITY

Ohno's Model Revisited: Measuring the Frequency of Potentially Adaptive Mutations under Various Mutational Drifts

(2008) Shimon Bershtein et al.   MOLECULAR BIOLOGY AND EVOLUTION

Heterogeneous Adaptive Trajectories of Small Populations on Complex Fitness Landscapes

(2008) Daniel E. Rozen et al.   PLoS One