Comprehensive experimental fitness landscape and evolutionary network for small RNA

RNA with iron(II) as a cofactor catalyses electron transfer

(2013) Chiaolong Hsiao et al.   Nature Chemistry

Cascade of Reduced Speed and Accuracy after Errors in Enzyme-Free Copying of Nucleic Acid Sequences

(2012) Kevin Leu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA Folding and Catalysis Mediated by Iron (II)

(2012) Shreyas S. Athavale et al.   PLoS One

Environmental change exposes beneficial epistatic interactions in a catalytic RNA

(2012) E. J. Hayden et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase

(2011) Trevor Hinkley et al.   NATURE GENETICS

Experimental illumination of a fitness landscape

(2011) R. T. Hietpas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic effect of mutations in evolving populations of RNA molecules

(2010) Michael Stich et al.   BMC EVOLUTIONARY BIOLOGY

Multiple translational products from a five-nucleotide ribozyme

(2010) R. M. Turk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Construction of Empirical RNA Fitness Landscapes

(2010) J. N. Pitt et al.   SCIENCE

Adaptive evolutionary walks require neutral intermediates in RNA fitness landscapes

(2010) Mark D. Rendel   THEORETICAL POPULATION BIOLOGY

Mathematical modeling of evolution. Solved and open problems

(2010) Peter Schuster   THEORY IN BIOSCIENCES

A genotype-to-phenotype map of in vitro selected RNA-cleaving DNAzymes: implications for accessing the target phenotype

(2009) Kenny Schlosser et al.   NUCLEIC ACIDS RESEARCH

The dawn of the RNA World: Toward functional complexity through ligation of random RNA oligomers

(2009) C. Briones et al.   RNA

Self-Sustained Replication of an RNA Enzyme

(2009) T. A. Lincoln et al.   SCIENCE

Strategies for measuring evolutionary conservation of RNA secondary structures

(2008) Andreas R Gruber et al.   BMC BIOINFORMATICS

A Recombination-Based Model for the Origin and Early Evolution of Genetic Information

(2008) Niles Lehman   CHEMISTRY & BIODIVERSITY

Imino proton exchange rates imply an induced-fit binding mechanism for the VEGF165-targeting aptamer, Macugen

(2008) Joon-Hwa Lee et al.   FEBS LETTERS

Evolutionary origins and directed evolution of RNA

(2008) Andrew D. Ellington et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Rapid in vivo exploration of a 5S rRNA neutral network

(2008) Zhengdong D. Zhang et al.   JOURNAL OF MICROBIOLOGICAL METHODS