Direct AMP-activated protein kinase activators: a review of evidence from the patent literature

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AMP-activated protein kinase undergoes nucleotide-dependent conformational changes

(2012) Lei Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

AMP-activated protein kinase modulators: a patent review (2006 – 2010)

(2011) Hee Yun et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A small molecule AMPK activator protects the heart against ischemia–reperfusion injury

(2011) Agnes S. Kim et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Structure of mammalian AMPK and its regulation by ADP

(2011) Bing Xiao et al.   NATURE

AMPK Is a Direct Adenylate Charge-Regulated Protein Kinase

(2011) J. S. Oakhill et al.   SCIENCE

AMP-activated protein kinase: also regulated by ADP?

(2011) D. Grahame Hardie et al.   TRENDS IN BIOCHEMICAL SCIENCES

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

 -Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)

(2010) J. S. Oakhill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMP-activated protein kinase activator A-769662 is an inhibitor of the Na+-K+-ATPase

(2009) Boubacar Benziane et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A-769662 activates AMPK β1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

(2009) Jonas T. Treebak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer

(2009) S. Fogarty et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Inhibitory Effects of A-769662, a Novel Activator of AMP-Activated Protein Kinase, on 3T3-L1 Adipogenesis

(2009) Yi Zhou et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Regulation of Rac1 by Simvastatin in Endothelial Cells

(2009) Ruqin Kou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated protein kinase inhibits TREK channels

(2009) Orsolya Kréneisz et al.   JOURNAL OF PHYSIOLOGY-LONDON

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells

(2008) Hélène Klein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

(2008) Xu Huang et al.   BIOCHEMICAL JOURNAL

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

(2008) John W. Scott et al.   CHEMISTRY & BIOLOGY

A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism

(2008) Daniel Moreno et al.   FEBS LETTERS

Small Molecule Antagonizes Autoinhibition and Activates AMP-activated Protein Kinase in Cells

(2008) Tao Pang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic Insight into Control of CFTR by AMPK

(2008) Patthara Kongsuphol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY