Targeting Energy Metabolic and Oncogenic Signaling Pathways in Triple-negative Breast Cancer by a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator

Adenosine 5'-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype

(2014) D. Sag et al.   JOURNAL OF IMMUNOLOGY

AMPK and Akt Determine Apoptotic Cell Death following Perturbations of One-Carbon Metabolism by Regulating ER Stress in Acute Lymphoblastic Leukemia

(2011) J. N. Kuznetsov et al.   MOLECULAR CANCER THERAPEUTICS

Pushing the Envelope in the mTOR Pathway: The Second Generation of Inhibitors

(2011) E. Vilar et al.   MOLECULAR CANCER THERAPEUTICS

Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells

(2010) Mahvash Zakikhani et al.   BREAST CANCER RESEARCH AND TREATMENT

Metformin Prevents Tobacco Carcinogen-Induced Lung Tumorigenesis

(2010) R. M. Memmott et al.   Cancer Prevention Research

The ability of preoperative magnetic resonance imaging to predict actual pathologic tumor size in women with newly diagnosed breast cancer.

(2010) L Vallow et al.   CANCER RESEARCH

New Strategies in Prostate Cancer: Targeting Lipogenic Pathways and the Energy Sensor AMPK

(2010) G. Zadra et al.   CLINICAL CANCER RESEARCH

Long-Term Metformin Use Is Associated With Decreased Risk of Breast Cancer

(2010) M. Bodmer et al.   DIABETES CARE

AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3)

(2010) A. Nerstedt et al.   DIABETOLOGIA

Regulation of mitochondrial biogenesis

(2010) François R. Jornayvaz et al.   Essays in Biochemistry

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION

Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators

(2010) Jih-Hwa Guh et al.   JOURNAL OF MEDICINAL CHEMISTRY

AMP-activated protein kinase mediates activity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α and nuclear respiratory factor 1 expression in rat visual cortical neurons

(2010) L. Yu et al.   NEUROSCIENCE

Akt and Autophagy Cooperate to Promote Survival of Drug-Resistant Glioma

(2010) Q.-W. Fan et al.   Science Signaling

AMP-activated protein kinase control of fat metabolism in skeletal muscle

(2009) D. M. Thomson et al.   Acta Physiologica

Mitochondrial dysfunction in human breast cancer cells and their transmitochondrial cybrids

(2009) Yewei Ma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Inflammation and Cancer: IL-6 and STAT3 Complete the Link

(2009) Jacqueline Bromberg et al.   CANCER CELL

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

LKB1 and Mammalian Target of Rapamycin As Predictive Factors for the Anticancer Efficacy of Metformin

(2009) Regan M. Memmott et al.   JOURNAL OF CLINICAL ONCOLOGY

Metformin in Breast Cancer: Time for Action

(2009) Pamela J. Goodwin et al.   JOURNAL OF CLINICAL ONCOLOGY

Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer

(2009) Sao Jiralerspong et al.   JOURNAL OF CLINICAL ONCOLOGY

Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells

(2009) N J Sullivan et al.   ONCOGENE

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

(2009) D. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogene Addiction

(2008) I. B. Weinstein et al.   CANCER RESEARCH

Phosphorylation of LKB1 at Serine 428 by Protein Kinase C-ζ Is Required for Metformin-Enhanced Activation of the AMP-Activated Protein Kinase in Endothelial Cells

(2008) Zhonglin Xie et al.   CIRCULATION

Targeting AMPK: A new therapeutic opportunity in breast cancer

(2008) Sirwan M. Hadad et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Small Molecule Antagonizes Autoinhibition and Activates AMP-activated Protein Kinase in Cells

(2008) Tao Pang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells

(2008) Aina S. Lihn et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

Twist is a transcriptional repressor of E-cadherin gene expression in breast cancer

(2007) Farhad Vesuna et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS