Oxidative C−H Activation Approach to Pyridone and Isoquinolone through an Iron-Catalyzed Coupling of Amides with Alkynes

How Low Does Iron Go? Chasing the Active Species in Fe-Catalyzed Cross-Coupling Reactions

(2015) Robin B. Bedford   ACCOUNTS OF CHEMICAL RESEARCH

Bidentate, Monoanionic Auxiliary-Directed Functionalization of Carbon–Hydrogen Bonds

(2015) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Iron-Catalyzed Directed Alkylation of Alkenes and Arenes with Alkylzinc Halides

(2015) Laurean Ilies et al.   ADVANCED SYNTHESIS & CATALYSIS

Iron Catalysis in Organic Synthesis

(2015) Ingmar Bauer et al.   CHEMICAL REVIEWS

Iron-Catalyzed Directed C2-Alkylation and Alkenylation of Indole with Vinylarenes and Alkynes

(2015) Mun Yee Wong et al.   ORGANIC LETTERS

Cobalt-Catalyzed, Aminoquinoline-Directed C(sp2)H Bond Alkenylation by Alkynes

(2014) Liene Grigorjeva et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The CH Activation/1,3-Diyne Strategy: Highly Selective Direct Synthesis of Diverse Bisheterocycles by RhIIICatalysis

(2014) Da-Gang Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron-Catalyzed C(sp2)H Alkylation of Carboxamides with Primary Electrophiles

(2014) Brendan M. Monks et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Extended π-Systems through C-H Activation

(2014) Yasutomo Segawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Unified Strategy for Iron-Catalyzed ortho-Alkylation of Carboxamides

(2014) Erin R. Fruchey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Directed Alkylation of Aromatic and Olefinic Carboxamides with Primary and Secondary Alkyl Tosylates, Mesylates, and Halides

(2014) Laurean Ilies et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed C(sp2)–H Bond Functionalization with Organoboron Compounds

(2014) Rui Shang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Polysubstituted Enynes through Iron-Catalyzed Carbomagnesiation of Conjugated Diynes

(2014) Eiichi Nakamura et al.   SYNLETT

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Rhodium(III)-Catalyzed Intramolecular Annulation through CH Activation: Total Synthesis of (±)-Antofine, (±)-Septicine, (±)-Tylophorine, and Rosettacin

(2012) Xianxiu Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of 2-(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist

(2012) Shigeki Hibi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Highly Diastereoselective Synthesis of Tetrahydropyridines by a C–H Activation–Cyclization–Reduction Cascade

(2012) Simon Duttwyler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mild Rh(III)-Catalyzed C–H Activation and Annulation with Alkyne MIDA Boronates: Short, Efficient Synthesis of Heterocyclic Boronic Acid Derivatives

(2012) Honggen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Annulation of α,β-Unsaturated Imines and Alkynes via Cobalt-Catalyzed Olefinic C–H Activation

(2012) Takeshi Yamakawa et al.   ORGANIC LETTERS

Versatile Pyrrole Synthesis through Ruthenium(II)-Catalyzed Alkene C–H Bond Functionalization on Enamines

(2012) Lianhui Wang et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Oxidative Annulation by Cleavage of CH/NH Bonds

(2011) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyridine synthesis from oximes and alkynesviarhodium(iii) catalysis: Cp* and Cptprovide complementary selectivity

(2011) Todd K. Hyster et al.   CHEMICAL COMMUNICATIONS

Iron-catalyzed aryl- and alkenyllithiation of alkynes and its application to benzosilole synthesis

(2011) Eiji Shirakawa et al.   CHEMICAL COMMUNICATIONS

C–H functionalization logic in total synthesis

(2011) Will R. Gutekunst et al.   CHEMICAL SOCIETY REVIEWS

Non-Innocent Ligands: New Opportunities in Iron Catalysis

(2011) Sébastien Blanchard et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Iron-Catalyzed Stereospecific Activation of Olefinic C–H Bonds with Grignard Reagent for Synthesis of Substituted Olefins

(2011) Laurean Ilies et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron–Copper Cooperative Catalysis in the Reactions of Alkyl Grignard Reagents: Exchange Reaction with Alkenes and Carbometalation of Alkynes

(2011) Eiji Shirakawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Chelation-Assisted Transformations Involving Ortho C–H Bond Activation: Regioselective Oxidative Cycloaddition of Aromatic Amides to Alkynes

(2011) Hirotaka Shiota et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Managing the scarcity of chemical elements

(2011) Eiichi Nakamura et al.   NATURE MATERIALS

Ruthenium-Catalyzed Oxidative Synthesis of 2-Pyridones through C–H/N–H Bond Functionalizations

(2011) Lutz Ackermann et al.   ORGANIC LETTERS

Iron-Catalyzed Oxidative Monoarylation of Primary Amines with Organozinc Reagents

(2011) Yuki Nakamura et al.   ORGANIC LETTERS

An improved catalyst architecture for rhodium(iii) catalyzed C–H activation and its application to pyridone synthesis

(2011) Todd K. Hyster et al.   Chemical Science

Direct C−H Transformation via Iron Catalysis

(2010) Chang-Liang Sun et al.   CHEMICAL REVIEWS

Nickel-Catalyzed, Directing-Group-Assisted [2+2+2] Cycloaddition of Imine and Alkynes

(2010) Laksmikanta Adak et al.   Chemistry-An Asian Journal

Low-Valent Iron-Catalyzed C−C Bond Formation−Addition, Substitution, and C−H Bond Activation

(2010) Eiichi Nakamura et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium(III)-Catalyzed Isoquinolone Synthesis: The N−O Bond as a Handle for C−N Bond Formation and Catalyst Turnover

(2010) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Arene and Alkene C−H Bond Functionalization Leading to Indoles and Pyrroles

(2010) David R. Stuart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Oxidative Cycloaddition of Benzamides and Alkynes via C−H/N−H Activation

(2010) Todd K. Hyster et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pyrrole Synthesis via Allylic sp3C−H Activation of Enamines Followed by Intermolecular Coupling with Unactivated Alkynes

(2010) Souvik Rakshit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 2-Pyridones and Iminoesters via Rh(III)-Catalyzed Oxidative Coupling between Acrylamides and Alkynes

(2010) Yan Su et al.   ORGANIC LETTERS

Coming of Age: Sustainable Iron-Catalyzed Cross-Coupling Reactions

(2009) Waldemar Maximilian Czaplik et al.   ChemSusChem

A new iron age

(2009) Carsten Bolm   Nature Chemistry

The Promise and Challenge of Iron-Catalyzed Cross Coupling

(2008) Benjamin D. Sherry et al.   ACCOUNTS OF CHEMICAL RESEARCH

Sustainable Metal Catalysis with Iron: From Rust to a Rising Star?

(2008) Stephan Enthaler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Dihydropyridines and Pyridines from Imines and Alkynes via C−H Activation

(2008) Denise A. Colby et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Stereoselective Formation of Bicyclic Enamines with Bridgehead Unsaturation via Tandem C−H Bond Activation/Alkenylation/Electrocyclization

(2008) Sirilata Yotphan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed One-Pot Synthesis of Substituted Pyridine Derivatives from α,β-Unsaturated Ketoximes and Alkynes

(2007) Kanniyappan Parthasarathy et al.   ORGANIC LETTERS