An introduction to physiologically-based pharmacokinetic models

Reduction of a Whole-Body Physiologically Based Pharmacokinetic Model to Stabilise the Bayesian Analysis of Clinical Data

(2015) Thierry Wendling et al.   AAPS Journal

Application of a Bayesian approach to physiological modelling of mavoglurant population pharmacokinetics

(2015) Thierry Wendling et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Predicting drug–drug interactions: application of physiologically based pharmacokinetic models under a systems biology approach

(2013) Karen Rowland Yeo et al.   Expert Review of Clinical Pharmacology

Recirculatory Pharmacokinetic Modeling

(2012) Tom C. Krejcie et al.   ANESTHESIA AND ANALGESIA

A physiologically-based recirculatory meta-model for nasal fentanyl in man

(2012) Richard N. Upton et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Measurement of Binding of Basic Drugs to Acidic Phospholipids Using Surface Plasmon Resonance and Incorporation of the Data into Mechanistic Tissue Composition Equations to Predict Steady-State Volume of Distribution

(2011) H. Small et al.   DRUG METABOLISM AND DISPOSITION

Tips and traps analyzing pediatric PK data

(2011) Brian J. Anderson et al.   PEDIATRIC ANESTHESIA

The Performance of Compartmental and Physiologically Based Recirculatory Pharmacokinetic Models for Propofol

(2010) Kenichi Masui et al.   ANESTHESIA AND ANALGESIA

Knowledge-driven approaches for the guidance of first-in-children dosing

(2010) Andrea N. Edginton   PEDIATRIC ANESTHESIA

Predicting Pharmacokinetics of Drugs Using Physiologically Based Modeling—Application to Food Effects

(2009) N. Parrott et al.   AAPS Journal

Prediction of Modified Release Pharmacokinetics and Pharmacodynamics from In Vitro, Immediate Release, and Intravenous Data

(2009) Viera Lukacova et al.   AAPS Journal

A Framework for Assessing Inter-individual Variability in Pharmacokinetics Using Virtual Human Populations and Integrating General Knowledge of Physical Chemistry, Biology, Anatomy, Physiology and Genetics: A Tale of ‘Bottom-Up’ vs ‘Top-Down’ Recognition of Covariates

(2009) Masoud Jamei et al.   Drug Metabolism and Pharmacokinetics

Physiology-Based Simulations of a Pathological Condition

(2008) Andrea N Edginton et al.   CLINICAL PHARMACOKINETICS

Human renal function maturation: a quantitative description using weight and postmenstrual age

(2008) Malin M. Rhodin et al.   PEDIATRIC NEPHROLOGY

Organ weights and blood flows of sheep and pig for physiological pharmacokinetic modelling

(2008) Richard N. Upton   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Mechanism-Based Concepts of Size and Maturity in Pharmacokinetics

(2007) B.J. Anderson et al.   Annual Review of Pharmacology and Toxicology

Development and specification of physiologically based pharmacokinetic models for use in risk assessment

(2007) Rebecca A. Clewell et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY