Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway
Authors
Keywords
Coenzyme A synthesis, <em class=EmphasisTypeItalic >Plasmodium falciparum</em>, Gametocytes, <em class=EmphasisTypeItalic >Trypanosoma brucei brucei</em>, <em class=EmphasisTypeItalic >Trypanosoma cruzi</em>, Drug discovery
Journal
Parasites & Vectors
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-11-17
DOI
10.1186/s13071-016-1860-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes
- (2016) Leonardo Lucantoni et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Non-symmetrical furan-amidines as novel leads for the treatment of cancer and malaria
- (2016) Soraya Alnabulsi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery
- (2016) Sandra Duffy et al. Nature Protocols
- A Pantetheinase-Resistant Pantothenamide with Potent, On-Target, and Selective Antiplasmodial Activity
- (2015) Cristiano J. Macuamule et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Splenic Retention of Plasmodium falciparum Gametocytes To Block the Transmission of Malaria
- (2015) Julien Duez et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Evaluation of chemotherapeutics in a three-dimensional breast cancer model
- (2015) Carrie J. Lovitt et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Novel pantothenate derivatives for anti-malarial chemotherapy
- (2015) Helmi E Pett et al. MALARIA JOURNAL
- Extracellular 4′-phosphopantetheine is a source for intracellular coenzyme A synthesis
- (2015) Balaji Srinivasan et al. Nature Chemical Biology
- Development and application of a sensitive, phenotypic, high-throughput image-based assay to identify compound activity against Trypanosoma cruzi amastigotes
- (2015) Melissa L. Sykes et al. International Journal for Parasitology-Drugs and Drug Resistance
- The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs
- (2015) Natalie Jane Spillman et al. International Journal for Parasitology-Drugs and Drug Resistance
- Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum Aminopeptidases, M1, M17 and M18
- (2015) Alessandro Paiardini et al. PLoS One
- Mutations in the P-Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone Antimalarials
- (2014) Erika L. Flannery et al. ACS Chemical Biology
- Fatty Acid Synthesis and Pyruvate Metabolism Pathways Remain Active in Dihydroartemisinin-Induced Dormant Ring Stages of Plasmodium falciparum
- (2014) Nanhua Chen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Repurposing the Open Access Malaria Box To Discover Potent Inhibitors of Toxoplasma gondii and Entamoeba histolytica
- (2014) Fabrice F. Boyom et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Identification of Cryptosporidium parvum Active Chemical Series by Repurposing the Open Access Malaria Box
- (2014) K. Bessoff et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides
- (2014) Kevin J. Saliba et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Identification of an Atg8-Atg3 Protein–Protein Interaction Inhibitor from the Medicines for Malaria Venture Malaria Box Active in Blood and Liver Stage Plasmodium falciparum Parasites
- (2014) Adelaide U.P. Hain et al. JOURNAL OF MEDICINAL CHEMISTRY
- Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development
- (2014) Sabrina D Lamour et al. MALARIA JOURNAL
- A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the Plasmodium falciparum Coenzyme A synthesis pathway
- (2014) Sabine Fletcher et al. MALARIA JOURNAL
- Diverse chemotypes disrupt ion homeostasis in the malaria parasite
- (2014) Adele M. Lehane et al. MOLECULAR MICROBIOLOGY
- Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
- (2014) S. Mok et al. SCIENCE
- Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum
- (2014) Akhil B. Vaidya et al. Nature Communications
- Orally Active Antischistosomal Early Leads Identified from the Open Access Malaria Box
- (2014) Katrin Ingram-Sieber et al. PLoS Neglected Tropical Diseases
- Simvastatin and GGTI-2133, a geranylgeranyl transferase inhibitor, increase erythrocyte deformability but reduce low O2 tension-induced ATP release
- (2013) K. M. Clapp et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- A miniaturized assay for measuring small molecule phosphorylation in the presence of complex matrices
- (2013) Christina Spry et al. ANALYTICAL BIOCHEMISTRY
- Antiapicoplast and Gametocytocidal Screening To Identify the Mechanisms of Action of Compounds within the Malaria Box
- (2013) Jessica D. Bowman et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay
- (2013) Leonardo Lucantoni et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum
- (2013) James I MacRae et al. BMC BIOLOGY
- Chloroquine in Cancer Therapy: A Double-Edged Sword of Autophagy
- (2013) T. Kimura et al. CANCER RESEARCH
- Citric Acid Cycle and Role of its Intermediates in Metabolism
- (2013) Muhammad Akram CELL BIOCHEMISTRY AND BIOPHYSICS
- Designing the next generation of medicines for malaria control and eradication
- (2013) Jeremy N Burrows et al. MALARIA JOURNAL
- Identification of inhibitors of Plasmodium falciparum gametocyte development
- (2013) Sandra Duffy et al. MALARIA JOURNAL
- Artemisinins: Pharmacological actions beyond anti-malarial
- (2013) Wanxing Eugene Ho et al. PHARMACOLOGY & THERAPEUTICS
- Pantothenamides Are Potent, On-Target Inhibitors of Plasmodium falciparum Growth When Serum Pantetheinase Is Inactivated
- (2013) Christina Spry et al. PLoS One
- The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected Diseases
- (2013) Thomas Spangenberg et al. PLoS One
- Lipid synthesis in protozoan parasites: A comparison between kinetoplastids and apicomplexans
- (2013) Srinivasan Ramakrishnan et al. PROGRESS IN LIPID RESEARCH
- Structural Modification of Pantothenamides Counteracts Degradation by Pantetheinase and Improves Antiplasmodial Activity
- (2013) Marianne de Villiers et al. ACS Medicinal Chemistry Letters
- In vivo biomarker expression patterns are preserved in 3D cultures of Prostate Cancer
- (2012) Louisa C.E. Windus et al. EXPERIMENTAL CELL RESEARCH
- Origin, composition, organization and function of the inner membrane complex of Plasmodium falciparum gametocytes
- (2012) M. K. Dearnley et al. JOURNAL OF CELL SCIENCE
- Anti-malarial drugs: how effective are they against Plasmodium falciparum gametocytes?
- (2012) Christopher L Peatey et al. MALARIA JOURNAL
- Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis
- (2010) Carola Huthmacher et al. BMC Systems Biology
- Malaria gametocytogenesis
- (2010) David A. Baker MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network
- (2010) Germán Plata et al. Molecular Systems Biology
- Priming the antimalarial pipeline
- (2010) David A. Fidock NATURE
- Development of an Alamar Blue™ Viability Assay in 384-Well Format for High Throughput Whole Cell Screening of Trypanosoma brucei brucei Bloodstream Form Strain 427
- (2009) Melissa L. Sykes et al. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
- The Human Malaria ParasitePlasmodium falciparumIs Not Dependent on Host Coenzyme A Biosynthesis
- (2009) Christina Spry et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Artemisinin Resistance inPlasmodium falciparumMalaria
- (2009) Arjen M. Dondorp et al. NEW ENGLAND JOURNAL OF MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search