Isothiourea-catalysed enantioselective pyrrolizine synthesis: synthetic and computational studies

Computational Insights into the Central Role of Nonbonding Interactions in Modern Covalent Organocatalysis

(2016) Daniel M. Walden et al.   ACCOUNTS OF CHEMICAL RESEARCH

Noncovalent Interactions in Organocatalysis and the Prospect of Computational Catalyst Design

(2016) Steven E. Wheeler et al.   ACCOUNTS OF CHEMICAL RESEARCH

Uniting C1-Ammonium Enolates and Transition Metal Electrophiles via Cooperative Catalysis: The Direct Asymmetric α-Allylation of Aryl Acetic Acid Esters

(2016) Kevin J. Schwarz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalyzed Formal [4+2] Cycloaddition ofin situGenerated Azoalkenes with Arylacetic Acids: An Efficient Approach to the Synthesis of 4,5-Dihydropyridazin-3(2H)-ones

(2015) Xuanyi Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Isothiourea-Catalysed Formal [3+2] Cycloadditions of Ammonium Enolates with Oxaziridines

(2015) Siobhan R. Smith et al.   CHEMISTRY-A EUROPEAN JOURNAL

Intermolecular Sulfur···Oxygen Interactions: Theoretical and Statistical Investigations

(2015) Xuejin Zhang et al.   Journal of Chemical Information and Modeling

A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design

(2015) Brett R. Beno et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phosphine-Catalyzed Addition/Cycloaddition Domino Reactions of β′-Acetoxy Allenoate: Highly Stereoselective Access to 2-Oxabicyclo[3.3.1]nonane and Cyclopenta[a]pyrrolizine

(2015) Yiting Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Facile Net Cycloaddition Approach to Optically Active 1,5-Benzothiazepines

(2015) Yukihiro Fukata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Three-Component Domino Process for the Pyrrolizine Skeleton via [3 + 2]-Cycloaddition–Enamine Cyclization Triggered by a Gold Catalyst

(2015) Kenji Sugimoto et al.   ORGANIC LETTERS

Intramolecular Friedel–Crafts Acylation Reaction Promoted by 1,1,1,3,3,3-Hexafluoro-2-propanol

(2015) Hashim F. Motiwala et al.   ORGANIC LETTERS

Stereoselective Lewis base catalyzed formal 1,3-dipolar cycloaddition of azomethine imines with mixed anhydrides

(2015) Lena Hesping et al.   Chemical Science

Design, synthesis and pharmacological evaluation of novel pyrrolizine derivatives as potential anticancer agents

(2014) Ahmed M. Gouda et al.   BIOORGANIC CHEMISTRY

Organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium or azolium enolates

(2014) Louis C. Morrill et al.   CHEMICAL SOCIETY REVIEWS

Stereodivergent Organocatalytic Intramolecular Michael Addition/Lactonization for the Asymmetric Synthesis of Substituted Dihydrobenzofurans and Tetrahydrofurans

(2014) Dorine Belmessieri et al.   CHEMISTRY-A EUROPEAN JOURNAL

Isothiourea-Catalyzed Asymmetric Synthesis of β-Lactams and β-Amino Esters from Arylacetic Acid Derivatives and N-Sulfonylaldimines

(2014) Siobhan R. Smith et al.   JOURNAL OF ORGANIC CHEMISTRY

Isothiourea-Mediated Asymmetric Functionalization of 3-Alkenoic Acids

(2014) Louis C. Morrill et al.   JOURNAL OF ORGANIC CHEMISTRY

An Isothiourea-Catalyzed Asymmetric [2,3]-Rearrangement of Allylic Ammonium Ylides

(2014) Thomas H. West et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoelectronic Effects Dictate Molecular Conformation and Biological Function of Heterocyclic Amides

(2014) Robert C. Reid et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acylammonium Salts as Dienophiles in Diels–Alder/Lactonization Organocascades

(2014) Mikail E. Abbasov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pyrrolizidine alkaloids

(2014) Jeremy Robertson et al.   NATURAL PRODUCT REPORTS

Synthesis of Di-, Tri-, and Tetrasubstituted Pyridines from (Phenylthio)carboxylic Acids and 2-[Aryl(tosylimino)methyl]acrylates

(2014) Daniel G. Stark et al.   ORGANIC LETTERS

Isothiourea-Mediated One-Pot Synthesis of Trifluoromethyl Substituted 2-Pyrones

(2014) Pei-Pei Yeh et al.   ORGANIC LETTERS

α-Ketophosphonates as Ester Surrogates: Isothiourea-Catalyzed Asymmetric Diester and Lactone Synthesis

(2014) Siobhan R. Smith et al.   ORGANIC LETTERS

Direct Catalytic Asymmetric Synthesis of N-Heterocycles from Commodity Acid Chlorides by Employing α,β-Unsaturated Acylammonium Salts

(2013) Sreekumar Vellalath et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isothiourea-Mediated One-Pot Synthesis of Functionalized Pyridines

(2013) Daniel G. Stark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyrrolizines: Promising scaffolds for anticancer drugs

(2013) Amany Belal et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Rapid assembly of complex cyclopentanes employing chiral, α,β-unsaturated acylammonium intermediates

(2013) Gang Liu et al.   Nature Chemistry

2-Arylacetic anhydrides as ammonium enolate precursors

(2013) Louis C. Morrill et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Telescoped Synthesis of Stereodefined Pyrrolidines

(2013) Dorine Belmessieri et al.   ORGANIC LETTERS

Anhydrides as α,β-unsaturated acyl ammonium precursors: isothiourea-promoted catalytic asymmetric annulation processes

(2013) Emily R. T. Robinson et al.   Chemical Science

Isothiourea-mediated asymmetric Michael-lactonisation of trifluoromethylenones: a synthetic and mechanistic study

(2013) Louis C. Morrill et al.   Chemical Science

Manifestation of Felkin-Anh Control in Enantioselective Acyl Transfer Catalysis: Kinetic Resolution of Carboxylic Acids

(2012) Xing Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dihydropyridones: Catalytic Asymmetric Synthesis, N- to C-Sulfonyl Transfer, and Derivatizations

(2012) Carmen Simal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amidines, isothioureas, and guanidines as nucleophilic catalysts

(2012) James E. Taylor et al.   CHEMICAL SOCIETY REVIEWS

Catalytic, Enantioselective N-Acylation of Lactams and Thiolactams Using Amidine-Based Catalysts

(2012) Xing Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Origin of Enantioselectivity in Benzotetramisole-Catalyzed Dynamic Kinetic Resolution of Azlactones

(2012) Peng Liu et al.   ORGANIC LETTERS

Catalytic asymmetric α-amination of carboxylic acids using isothioureas

(2012) Louis C. Morrill et al.   Chemical Science

Investigations on cytotoxicity and anti-inflammatory potency of licofelone derivatives

(2011) Wukun Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Organocatalytic Functionalization of Carboxylic Acids: Isothiourea-Catalyzed Asymmetric Intra- and Intermolecular Michael Addition−Lactonizations

(2011) Dorine Belmessieri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic Resolution of Racemic α-Arylalkanoic Acids with Achiral Alcohols via the Asymmetric Esterification Using Carboxylic Anhydrides and Acyl-Transfer Catalysts

(2010) Isamu Shiina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Asymmetric Synthesis of Chiral Pyrrolizines by Cascade Conjugate Addition−Aldol Reactions

(2010) Ju-Yeon Bae et al.   ORGANIC LETTERS

Friedel−Crafts Acylation of Pyrroles and Indoles using 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) as a Nucleophilic Catalyst

(2010) James E. Taylor et al.   ORGANIC LETTERS

Effects of Methyl Substituents on the Activity and Enantioselectivity of Homobenzotetramisole-Based Catalysts in the Kinetic Resolution of Alcohols

(2009) Yuhua Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Isothiourea-Catalyzed Enantioselective Carboxy Group Transfer

(2009) Caroline Joannesse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel substituted and fused pyrrolizine derivatives: Synthesis, anti-inflammatory and ulcerogenecity studies

(2009) Safinaz E. Abbas et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Simultaneous σ-hole and hydrogen bonding by sulfur- and selenium-containing heterocycles

(2008) Jane S. Murray et al.   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

Small Molecule Conformational Preferences Derived from Crystal Structure Data. A Medicinal Chemistry Focused Analysis

(2008) Ken A. Brameld et al.   Journal of Chemical Information and Modeling

Homobenzotetramisole:  An Effective Catalyst for Kinetic Resolution of Aryl-Cycloalkanols

(2008) Vladimir B. Birman et al.   ORGANIC LETTERS