Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex

MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence

(2016) Bernard S. Marasa et al.   Aging-US

microRNA-1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers

(2015) Nijiro Nohata et al.   Oncotarget

Mutant p53 in Cancer: New Functions and Therapeutic Opportunities

(2014) Patricia A.J. Muller et al.   CANCER CELL

Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer

(2014) Masaki Mori et al.   CELL

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist

(2014) V Ubertini et al.   ONCOGENE

A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis

(2014) M Subramanian et al.   ONCOGENE

The DEAD box proteins DDX5 (p68) and DDX17 (p72): Multi-tasking transcriptional regulators

(2013) Frances V. Fuller-Pace   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

MiR-200, a new star miRNA in human cancer

(2013) Xiangling Feng et al.   CANCER LETTERS

Downregulation of microRNA-515-5p by the Estrogen Receptor Modulates Sphingosine Kinase 1 and Breast Cancer Cell Proliferation

(2013) F. G. Pinho et al.   CANCER RESEARCH

MicroRNA-218 Inhibits Glioma Invasion, Migration, Proliferation, and Cancer Stem-like Cell Self-Renewal by Targeting the Polycomb Group Gene Bmi1

(2013) Y. Tu et al.   CANCER RESEARCH

Mutant p53 Regulates Dicer through p63-dependent and -independent Mechanisms to Promote an Invasive Phenotype

(2013) Patricia A. J. Muller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p53siRNA therapy reduces cell proliferation, migration and induces apoptosis in triple negative breast cancer cells

(2013) Cornelia Braicu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells

(2013) S Masciarelli et al.   ONCOGENE

Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression

(2013) W Wang et al.   Cell Death & Disease

Glucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapy

(2013) A Garufi et al.   Cell Death & Disease

Down-regulation of miR-517a and miR-517c promotes proliferation of hepatocellular carcinoma cells via targeting Pyk2

(2012) Rui-Fang Liu et al.   CANCER LETTERS

miR-518b is down-regulated, and involved in cell proliferation and invasion by targeting Rap1b in esophageal squamous cell carcinoma

(2012) Mingxin Zhang et al.   FEBS LETTERS

BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex

(2012) Shinji Kawai et al.   JOURNAL OF CELL BIOLOGY

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

Mutant p53 drives invasion in breast tumors through up-regulation of miR-155

(2012) P M Neilsen et al.   ONCOGENE

Mutant p53 gain-of-function induces epithelial–mesenchymal transition through modulation of the miR-130b–ZEB1 axis

(2012) P Dong et al.   ONCOGENE

Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop

(2012) J Zhang et al.   ONCOGENE

A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer

(2011) Javier E. Girardini et al.   CANCER CELL

MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function

(2011) S Donzelli et al.   CELL DEATH AND DIFFERENTIATION

CPTH6, a Thiazole Derivative, Induces Histone Hypoacetylation and Apoptosis in Human Leukemia Cells

(2011) D. Trisciuoglio et al.   CLINICAL CANCER RESEARCH

MicroRNA-142-3p, a new regulator of RAC1, suppresses the migration and invasion of hepatocellular carcinoma cells

(2011) Lifen Wu et al.   FEBS LETTERS

RNA helicases p68 and p72: multifunctional proteins with important implications for cancer development

(2011) Frances V Fuller-Pace et al.   Future Oncology

miR-143 Overexpression Impairs Growth of Human Colon Carcinoma Xenografts in Mice with Induction of Apoptosis and Inhibition of Proliferation

(2011) Pedro M. Borralho et al.   PLoS One

MicroRNA-519c Suppresses Hypoxia-Inducible Factor-1α Expression and Tumor Angiogenesis

(2010) Shih-Ting Cha et al.   CANCER RESEARCH

Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy

(2010) Gianluca Bossi et al.   CELL CYCLE

miR-519 suppresses tumor growth by reducing HuR levels

(2010) Kotb Abdelmohsen et al.   CELL CYCLE

Mutant p53-induced Up-regulation of Mitogen-activated Protein Kinase Kinase 3 Contributes to Gain of Function

(2010) Aymone Gurtner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

(2010) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR-218 Inhibits Invasion and Metastasis of Gastric Cancer by Targeting the Robo1 Receptor

(2010) Jun Tie et al.   PLoS Genetics

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

(2009) Maddalena Adorno et al.   CELL

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE