Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53

Cyclooxygenase-2 promotes tumor growth and suppresses tumor immunity

(2015) Bing Liu et al.   Cancer Cell International

TP53 alterations in pancreatic acinar cell carcinoma: new insights into the molecular pathology of this rare cancer

(2015) Stefano La Rosa et al.   VIRCHOWS ARCHIV

Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis

(2015) Susan Morvaridi et al.   Scientific Reports

Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation

(2015) Kevin Myant et al.   Cell Reports

Pancreatic Adenocarcinoma

(2015) David P. Ryan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Progressive Metaplastic and Dysplastic Changes in Mouse Pancreas Induced by Cyclooxygenase-2 Overexpression

(2015) Jennifer K.L. Colby et al.   NEOPLASIA

Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo

(2014) T J Phesse et al.   CELL DEATH AND DIFFERENTIATION

Drugging the undruggable RAS: Mission Possible?

(2014) Adrienne D. Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Pathology and genetics of pancreatic neoplasms with acinar differentiation

(2014) Laura D. Wood et al.   SEMINARS IN DIAGNOSTIC PATHOLOGY

A High-Fat Diet Activates Oncogenic Kras and COX2 to Induce Development of Pancreatic Ductal Adenocarcinoma in Mice

(2013) Bincy Philip et al.   GASTROENTEROLOGY

Whole-exome sequencing of pancreatic neoplasms with acinar differentiation

(2013) Yuchen Jiao et al.   JOURNAL OF PATHOLOGY

Oncogenic K-Ras requires activation for enhanced activity

(2013) H Huang et al.   ONCOGENE

Activation of Nuclear Factor-κB in Acinar Cells Increases the Severity of Pancreatitis in Mice

(2012) Haojie Huang et al.   GASTROENTEROLOGY

Role of Nitrative and Oxidative DNA Damage in Inflammation-Related Carcinogenesis

(2012) Mariko Murata et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

An NF-κB pathway–mediated positive feedback loop amplifies Ras activity to pathological levels in mice

(2012) Jaroslaw Daniluk et al.   JOURNAL OF CLINICAL INVESTIGATION

Prostaglandins and Inflammation

(2011) Emanuela Ricciotti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inactivation ofBrca2cooperates withTrp53R172Hto induce invasive pancreatic ductal adenocarcinomas in mice

(2011) Georg Feldmann et al.   CANCER BIOLOGY & THERAPY

Inactivation of Brca2 Promotes Trp53-Associated but Inhibits KrasG12D-Dependent Pancreatic Cancer Development in Mice

(2011) Matthew Rowley et al.   GASTROENTEROLOGY

Acinar-to-ductal metaplasia accompanies c-myc-induced exocrine pancreatic cancer progression in transgenic rodents

(2011) Paul J. Grippo et al.   INTERNATIONAL JOURNAL OF CANCER

PTEN Loss Accelerates KrasG12D-Induced Pancreatic Cancer Development

(2010) R. Hill et al.   CANCER RESEARCH

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

(2009) F. Colotta et al.   CARCINOGENESIS

Detection of K-ras mutations in azoxymethane-induced aberrant crypt foci in mice using LNA-mediated real-time PCR clamping and mutant-specific probes

(2009) Ying Hu et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Trp53 Deletion Stimulates the Formation of Metastatic Pancreatic Tumors

(2008) Jennifer P. Morton et al.   AMERICAN JOURNAL OF PATHOLOGY

Overexpression of Interleukin-1β in the Murine Pancreas Results in Chronic Pancreatitis

(2008) Frederic Marrache et al.   GASTROENTEROLOGY

Robust acinar cell transgene expression of CreErT via BAC recombineering

(2008) Baoan Ji et al.   GENESIS