Inactivation ofBrca2cooperates withTrp53R172Hto induce invasive pancreatic ductal adenocarcinomas in mice

Inactivation of Brca2 Promotes Trp53-Associated but Inhibits KrasG12D-Dependent Pancreatic Cancer Development in Mice

(2011) Matthew Rowley et al.   GASTROENTEROLOGY

Germline Brca2 Heterozygosity Promotes KrasG12D -Driven Carcinogenesis in a Murine Model of Familial Pancreatic Cancer

(2010) Ferdinandos Skoulidis et al.   CANCER CELL

Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer

(2010) M. C. Villarroel et al.   MOLECULAR CANCER THERAPEUTICS

PARP inhibitor olaparib is safe and effective in patients with BRCA1 and BRCA2 mutations

(2010) Lisa Hutchinson   Nature Reviews Clinical Oncology

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras

(2009) Sharon Y. Gidekel Friedlander et al.   CANCER CELL

The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer

(2009) V. Fendrich et al.   GUT

The Hedgehog Pathway and Pancreatic Cancer

(2009) Manuel Hidalgo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pancreatic Cancer

(2008) Anirban Maitra et al.   Annual Review of Pathology-Mechanisms of Disease

Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl

(2008) C. Slape et al.   BLOOD

Molecular Genetics of Pancreatic Ductal Adenocarcinomas and Recent Implications for Translational Efforts

(2008) Georg Feldmann et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice

(2008) N. Habbe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE