miR-127 promotes EMT and stem-like traits in lung cancer through a feed-forward regulatory loop

A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development

(2015) M. Ito et al.   DEVELOPMENT

Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence

(2015) Masahiro Marshall Nakagawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comprehensive genomic profiles of small cell lung cancer

(2015) Julie George et al.   NATURE

A set of NF-κB–regulated microRNAs induces acquired TRAIL resistance in Lung cancer

(2015) Young-Jun Jeon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proinflammatory Signaling Regulates Hematopoietic Stem Cell Emergence

(2014) Raquel Espín-Palazón et al.   CELL

Metformin Sensitizes EGFR-TKI-Resistant Human Lung Cancer Cells In Vitro and In Vivo through Inhibition of IL-6 Signaling and EMT Reversal

(2014) L. Li et al.   CLINICAL CANCER RESEARCH

MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis

(2014) Chi-Hong Chao et al.   JOURNAL OF CLINICAL INVESTIGATION

MiR-127 Modulates Macrophage Polarization and Promotes Lung Inflammation and Injury by Activating the JNK Pathway

(2014) Hangjie Ying et al.   JOURNAL OF IMMUNOLOGY

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

An integrin β3–KRAS–RalB complex drives tumour stemness and resistance to EGFR inhibition

(2014) Laetitia Seguin et al.   NATURE CELL BIOLOGY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

EGF receptor uses SOS1 to drive constitutive activation of NF B in cancer cells

(2014) S. De et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

(2014) J. Zhang et al.   SCIENCE

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

(2014) E. C. de Bruin et al.   SCIENCE

Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell-like Properties in Cancer Cells

(2013) K. Shien et al.   CANCER RESEARCH

MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling

(2013) Su Jung Song et al.   CELL

Hepatocyte nuclear factor-4α reverses malignancy of hepatocellular carcinoma through regulating miR-134 in the DLK1-DIO3 region

(2013) Chuan Yin et al.   HEPATOLOGY

MicroRNA-433 Inhibits Liver Cancer Cell Migration by Repressing the Protein Expression and Function of cAMP Response Element-binding Protein

(2013) Zhihong Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA Signature Obtained From the Comparison of Aggressive With Indolent Non-Hodgkin Lymphomas: Potential Prognostic Value in Mantle-Cell Lymphoma

(2013) Rashmi S. Goswami et al.   JOURNAL OF CLINICAL ONCOLOGY

Epithelial-Mesenchymal Transition Induced by TNF-  Requires NF- B-Mediated Transcriptional Upregulation of Twist1

(2012) C.-W. Li et al.   CANCER RESEARCH

TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets

(2012) Libing Song et al.   JOURNAL OF CLINICAL INVESTIGATION

EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis

(2012) Weiwei Yang et al.   MOLECULAR CELL

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

(2012) Charles M Rudin et al.   NATURE GENETICS

A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer

(2011) Joaquim Calbo et al.   CANCER CELL

Gap Junction-Mediated Import of MicroRNA from Bone Marrow Stromal Cells Can Elicit Cell Cycle Quiescence in Breast Cancer Cells

(2011) P. K. Lim et al.   CANCER RESEARCH

Small-cell lung cancer

(2011) Jan P van Meerbeeck et al.   LANCET

FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR

(2011) Trever G. Bivona et al.   NATURE

EGFR and MET receptor tyrosine kinase–altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers

(2011) Michela Garofalo et al.   NATURE MEDICINE

Tobacco Smoke Promotes Lung Tumorigenesis by Triggering IKKβ- and JNK1-Dependent Inflammation

(2010) Hiroyuki Takahashi et al.   CANCER CELL

Identification of USP18 as an Important Regulator of the Susceptibility to IFN-  and Drug-Induced Apoptosis

(2010) H. Potu et al.   CANCER RESEARCH

Involvement of NF-κB/miR-448 regulatory feedback loop in chemotherapy-induced epithelial–mesenchymal transition of breast cancer cells

(2010) Q-Q Li et al.   CELL DEATH AND DIFFERENTIATION

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

TNFAIP3(A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

(2009) Roland Schmitz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma

(2009) Etienne Meylan et al.   NATURE

Personalized Medicine and Inhibition ofEGFRSignaling in Lung Cancer

(2009) Adi F. Gazdar   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA-127 modulates fetal lung development

(2009) Manoj Bhaskaran et al.   PHYSIOLOGICAL GENOMICS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

A skin microRNA promotes differentiation by repressing ‘stemness’

(2008) Rui Yi et al.   NATURE

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

The Evolution of the DLK1-DIO3 Imprinted Domain in Mammals

(2008) Carol A Edwards et al.   PLOS BIOLOGY