The IKAROS Interaction with a Complex Including Chromatin Remodeling and Transcription Elongation Activities Is Required for Hematopoiesis

Cutting Edge: Ikaros Is a Regulator of Th2 Cell Differentiation

(2014) M. R. Quirion et al.   JOURNAL OF IMMUNOLOGY

Stage-specific control of early B cell development by the transcription factor Ikaros

(2014) Tanja A Schwickert et al.   NATURE IMMUNOLOGY

Regulation of CDK9 Activity by Phosphorylation and Dephosphorylation

(2014) Sergei Nekhai et al.   Biomed Research International

Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation

(2013) I. Ferreiros-Vidal et al.   BLOOD

Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

(2013) S. Malinge et al.   BLOOD

Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals

(2013) Beate Heizmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Direct Protein Interactions Are Responsible for Ikaros-GATA and Ikaros-Cdk9 Cooperativeness in Hematopoietic Cells

(2013) Stefania Bottardi et al.   MOLECULAR AND CELLULAR BIOLOGY

Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting

(2013) Shwu-Yuan Wu et al.   MOLECULAR CELL

Modification of Enhancer Chromatin: What, How, and Why?

(2013) Eliezer Calo et al.   MOLECULAR CELL

USF1 and hSET1A Mediated Epigenetic Modifications Regulate Lineage Differentiation and HoxB4 Transcription

(2013) Changwang Deng et al.   PLoS Genetics

RNA Polymerase II Elongation Control

(2012) Qiang Zhou et al.   Annual Review of Biochemistry

Set3 HDAC Mediates Effects of Overlapping Noncoding Transcription on Gene Induction Kinetics

(2012) TaeSoo Kim et al.   CELL

NuRD and Pluripotency: A Complex Balancing Act

(2012) Guang Hu et al.   Cell Stem Cell

NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment

(2012) Nicola Reynolds et al.   Cell Stem Cell

GATA-1 Utilizes Ikaros and Polycomb Repressive Complex 2 To Suppress Hes1 and To Promote Erythropoiesis

(2012) J. Ross et al.   MOLECULAR AND CELLULAR BIOLOGY

The super elongation complex (SEC) family in transcriptional control

(2012) Zhuojuan Luo et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II

(2012) Stéphane Larochelle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation

(2011) A. M. Pilon et al.   BLOOD

Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells

(2011) Ozlem Yildirim et al.   CELL

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

(2011) Noa Novershtern et al.   CELL

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

(2011) W. Wu et al.   GENOME RESEARCH

The Ikaros gene family: Transcriptional regulators of hematopoiesis and immunity

(2011) Liza B. John et al.   MOLECULAR IMMUNOLOGY

Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis

(2011) Jiangwen Zhang et al.   NATURE IMMUNOLOGY

Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation

(2011) Stefania Bottardi et al.   NUCLEIC ACIDS RESEARCH

Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175

(2011) Tatiana Ammosova et al.   PLoS One

c-Kit-Mediated Functional Positioning of Stem Cells to Their Niches Is Essential for Maintenance and Regeneration of Adult Hematopoiesis

(2011) Yuki Kimura et al.   PLoS One

c-Myc Regulates Transcriptional Pause Release

(2010) Peter B. Rahl et al.   CELL

Awakening lineage potential by Ikaros-mediated transcriptional priming

(2010) Toshimi Yoshida et al.   CURRENT OPINION IN IMMUNOLOGY

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

(2010) Sebastian Carotta et al.   IMMUNITY

AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

(2010) Chengqi Lin et al.   MOLECULAR CELL

HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear

(2010) Iván D’Orso et al.   Viruses-Basel

Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3

(2009) Kristina Masson et al.   CELLULAR SIGNALLING

NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development

(2009) Annarita Miccio et al.   EMBO JOURNAL

Genome-wide Lineage-Specific Transcriptional Networks Underscore Ikaros-Dependent Lymphoid Priming in Hematopoietic Stem Cells

(2009) Samuel Yao-Ming Ng et al.   IMMUNITY

Ikaros Stability and Pericentromeric Localization Are Regulated by Protein Phosphatase 1

(2009) Marcela Popescu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion ofIKZF1and Prognosis in Acute Lymphoblastic Leukemia

(2009) Charles G. Mullighan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of the Long-Term Reconstituting Subset of Hematopoietic Stem Cells with CD150

(2009) Peter Papathanasiou et al.   STEM CELLS

Ikaros negatively regulates inducible nitric oxide synthase expression in macrophages: Involvement of Ikaros phosphorylation by casein kinase 2

(2008) S.-J. Cho et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

PP2B and PP1  cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling

(2008) R. Chen et al.   GENES & DEVELOPMENT

Recruitment of Ikaros to Pericentromeric Heterochromatin Is Regulated by Phosphorylation

(2008) Zafer Gurel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ikaros and GATA-1 Combinatorial Effect Is Required for Silencing of Human  -Globin Genes

(2008) S. Bottardi et al.   MOLECULAR AND CELLULAR BIOLOGY

Exchange of GATA Factors Mediates Transitions in Looped Chromatin Organization at a Developmentally Regulated Gene Locus

(2008) Huie Jing et al.   MOLECULAR CELL

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

(2008) Charles G. Mullighan et al.   NATURE