Uric acid and transforming growth factor in fructose-induced production of reactive oxygen species in skeletal muscle

Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress

(2015) Natasha Jaiswal et al.   APOPTOSIS

A pilot study on the impact of a low fructose diet and allopurinol on clinic blood pressure among overweight and prehypertensive subjects: a randomized placebo controlled trial

(2015) Magdalena Madero et al.   Journal of the American Society of Hypertension

Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system

(2015) Hany M El-Bassossy et al.   Journal of Translational Medicine

Fructose-Containing Sugars and Cardiovascular Disease

(2015) James M Rippe et al.   Advances in Nutrition

Effect of Fructose on Established Lipid Targets: A Systematic Review and Meta‐Analysis of Controlled Feeding Trials

(2015) Laura Chiavaroli et al.   Journal of the American Heart Association

Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat

(2014) Blair E. Warren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

(2014) M Ogrunc et al.   CELL DEATH AND DIFFERENTIATION

Sugar, Uric Acid, and the Etiology of Diabetes and Obesity

(2013) R. J. Johnson et al.   DIABETES

The role of uric acid in the pathogenesis of human cardiovascular disease

(2013) Mehmet Kanbay et al.   HEART

Reducing Serum Uric Acid Attenuates TGF-β1-Induced Profibrogenic Progression in Type 2 Diabetic Nephropathy

(2013) Su-Mi Kim et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Evidence to support a food-based dietary guideline on sugar consumption in South Africa

(2012) Nelia P Steyn et al.   BMC PUBLIC HEALTH

‘Catalytic’ doses of fructose may benefit glycaemic control without harming cardiometabolic risk factors: a small meta-analysis of randomised controlled feeding trials

(2012) John L. Sievenpiper et al.   BRITISH JOURNAL OF NUTRITION

Grape Polyphenols Prevent Fructose-Induced Oxidative Stress and Insulin Resistance in First-Degree Relatives of Type 2 Diabetic Patients

(2012) M. Hokayem et al.   DIABETES CARE

Increased hepatic de novo lipogenesis and mitochondrial efficiency in a model of obesity induced by diets rich in fructose

(2012) Raffaella Crescenzo et al.   EUROPEAN JOURNAL OF NUTRITION

Uric Acid Induces Hepatic Steatosis by Generation of Mitochondrial Oxidative Stress

(2012) Miguel A. Lanaspa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells

(2012) Yong Zhang et al.   Lipids in Health and Disease

Impact of high glucose and transforming growth factor–β on bioenergetic profiles in podocytes

(2012) Nicole Stieger et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Uric Acid-Induced Endothelial Dysfunction Is Associated with Mitochondrial Alterations and Decreased Intracellular ATP Concentrations

(2012) Laura Gabriela Sánchez-Lozada et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice

(2012) Yan Y. Lam et al.   PLoS One

Uric Acid Stimulates Fructokinase and Accelerates Fructose Metabolism in the Development of Fatty Liver

(2012) Miguel A. Lanaspa et al.   PLoS One

Rapid Increases in Overweight and Obesity Among South African Adolescents: Comparison of Data From the South African National Youth Risk Behaviour Survey in 2002 and 2008

(2011) Sasiragha P. Reddy et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Hyperuricemia as a Mediator of the Proinflammatory Endocrine Imbalance in the Adipose Tissue in a Murine Model of the Metabolic Syndrome

(2011) W. Baldwin et al.   DIABETES

Uric Acid and Fructose: Potential Biological Mechanisms

(2011) Miguel A. Lanaspa et al.   SEMINARS IN NEPHROLOGY

Hepatic Oxidative Stress in Fructose-Induced Fatty Liver Is Not Caused by Sulfur Amino Acid Insufficiency

(2011) Sachin S. Kunde et al.   Nutrients

Oxidative stress and aging: Is methylglyoxal the hidden enemy?This review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.

(2010) Kaushik M. Desai et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

(2010) Tetsuro Ago et al.   CIRCULATION RESEARCH

The Role of High-Fructose Corn Syrup in Metabolic Syndrome and Hypertension

(2010) Leon Ferder et al.   CURRENT HYPERTENSION REPORTS

The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes

(2010) Mary-Elizabeth Patti et al.   ENDOCRINE REVIEWS

Metabolic Effects of Fructose and the Worldwide Increase in Obesity

(2010) Luc Tappy et al.   PHYSIOLOGICAL REVIEWS

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

(2010) Robert B. Hamanaka et al.   TRENDS IN BIOCHEMICAL SCIENCES

Fructose induced lipogenesis: from sugar to fat to insulin resistance

(2010) Varman T. Samuel   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Hypothesis: Could Excessive Fructose Intake and Uric Acid Cause Type 2 Diabetes?

(2009) Richard J. Johnson et al.   ENDOCRINE REVIEWS

Abnormal hepatic energy homeostasis in type 2 diabetes

(2009) Julia Szendroedi et al.   HEPATOLOGY

Transforming Growth Factor-β/Smad3 Signaling Regulates Insulin Gene Transcription and Pancreatic Islet β-Cell Function

(2009) Huei-Min Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells

(2009) Sandro M. Hirabara et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Increased prevalence of mutant null alleles that cause hereditary fructose intolerance in the American population

(2009) Erin M. Coffee et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Ketohexokinase-Dependent Metabolism of Fructose Induces Proinflammatory Mediators in Proximal Tubular Cells

(2009) P. Cirillo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NAD(P)H Oxidase Mediates TGF- 1-Induced Activation of Kidney Myofibroblasts

(2009) C. D. Bondi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy

(2009) Kimberley Mellor et al.   NUTRITION

High-fructose corn syrup: is this what's for dinner?

(2008) Kiyah J Duffey et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Endocrine and metabolic effects of consuming beverages sweetened with fructose, glucose, sucrose, or high-fructose corn syrup

(2008) Kimber L Stanhope et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Fructose ingestion acutely elevates blood pressure in healthy young humans

(2008) Clive M. Brown et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome

(2008) Heiko Bugger et al.   CLINICAL SCIENCE

Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells

(2008) A.S. Pimenta et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells

(2008) Rafael Herling Lambertucci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity

(2008) Irene Carmona-Cuenca et al.   JOURNAL OF HEPATOLOGY