Kinetics of transcription initiation directed by multiplecis-regulatory elements on theglnAp2promoter

Measurement of gene regulation in individual cells reveals rapid switching between promoter states

(2016) Leonardo A. Sepúlveda et al.   SCIENCE

A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting

(2016) Katjana Tantale et al.   Nature Communications

A continuum model of transcriptional bursting

(2016) Adam M Corrigan et al.   eLife

Architecture of the RNA polymerase II–Mediator core initiation complex

(2015) C. Plaschka et al.   NATURE

Looping Back to Leap Forward: Transcription Enters a New Era

(2014) Michael Levine et al.   CELL

Molecular Mechanisms of Transcription through Single-Molecule Experiments

(2014) Manchuta Dangkulwanich et al.   CHEMICAL REVIEWS

DNA Recognition by a σ54 Transcriptional Activator from Aquifex aeolicus

(2014) Natasha K. Vidangos et al.   JOURNAL OF MOLECULAR BIOLOGY

Reconciling the concurrent fast and slow cycling of proteins on gene promoters

(2014) Y. Wang et al.   Journal of the Royal Society Interface

DNase Footprint Signatures Are Dictated by Factor Dynamics and DNA Sequence

(2014) Myong-Hee Sung et al.   MOLECULAR CELL

Transcription factors without footprints

(2014) Nicole Rusk   NATURE METHODS

Domain movements of the enhancer-dependent sigma factor drive DNA delivery into the RNA polymerase active site: insights from single molecule studies

(2014) Amit Sharma et al.   NUCLEIC ACIDS RESEARCH

Single-molecule tracking of the transcription cycle by sub-second RNA detection

(2014) Zhengjian Zhang et al.   eLife

A high-resolution map of the three-dimensional chromatin interactome in human cells

(2013) Fulai Jin et al.   NATURE

CoSMoS Unravels Mysteries of Transcription Initiation

(2012) Richard L. Gourse et al.   CELL

Mechanism of Transcription Initiation at an Activator-Dependent Promoter Defined by Single-Molecule Observation

(2012) Larry J. Friedman et al.   CELL

The Role of Bacterial Enhancer Binding Proteins as Specialized Activators of  54-Dependent Transcription

(2012) M. Bush et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Using Gene Expression Noise to Understand Gene Regulation

(2012) B. Munsky et al.   SCIENCE

Opening and Closing of the Bacterial RNA Polymerase Clamp

(2012) A. Chakraborty et al.   SCIENCE

Dynamic Mechanism for the Transcription Apparatus Orchestrating Reliable Responses to Activators

(2012) Yaolai Wang et al.   Scientific Reports

Central dogma at the single-molecule level in living cells

(2011) Gene-Wei Li et al.   NATURE

Stochastic Pulse Regulation in Bacterial Stress Response

(2011) J. C. W. Locke et al.   SCIENCE

Inducible gene expression: diverse regulatory mechanisms

(2010) Vikki M. Weake et al.   NATURE REVIEWS GENETICS

Imaging Transcription in Living Cells

(2009) Xavier Darzacq et al.   Annual Review of Biophysics

Transcription Dynamics

(2009) Gordon L. Hager et al.   MOLECULAR CELL

Defining mechanisms that regulate RNA polymerase II transcription in vivo

(2009) Nicholas J. Fuda et al.   NATURE

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Discrete state model and accurate estimation of loop entropy of RNA secondary structures

(2008) Jian Zhang et al.   JOURNAL OF CHEMICAL PHYSICS

Organization of an Activator-Bound RNA Polymerase Holoenzyme

(2008) Daniel Bose et al.   MOLECULAR CELL

Modus operandi of the bacterial RNA polymerase containing the σ54promoter-specificity factor

(2008) Sivaramesh Wigneshweraraj et al.   MOLECULAR MICROBIOLOGY

Single-RNA counting reveals alternative modes of gene expression in yeast

(2008) Daniel Zenklusen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY