Post-translational control of genetic circuits usingPotyvirusproteases

Locked and proteolysis-based transcription activator-like effector (TALE) regulation

(2016) Jan Lonzarić et al.   NUCLEIC ACIDS RESEARCH

Genetic circuit design automation

(2016) A. A. K. Nielsen et al.   SCIENCE

The development and characterization of synthetic minimal yeast promoters

(2015) Heidi Redden et al.   Nature Communications

Memory and Combinatorial Logic Based on DNA Inversions: Dynamics and Evolutionary Stability

(2015) Jesus Fernandez-Rodriguez et al.   ACS Synthetic Biology

Coexpression of cellulases in Pichia pastoris as a self-processing protein fusion

(2015) Juliana de Amorim Araújo et al.   AMB Express

Chemical Biology Strategies for Posttranslational Control of Protein Function

(2014) Rishi Rakhit et al.   CHEMISTRY & BIOLOGY

Synthetic analog and digital circuits for cellular computation and memory

(2014) Oliver Purcell et al.   CURRENT OPINION IN BIOTECHNOLOGY

Genetic Encoding of Photocaged Cysteine Allows Photoactivation of TEV Protease in Live Mammalian Cells

(2014) Duy P. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase

(2014) T. H. Segall-Shapiro et al.   Molecular Systems Biology

Multi-input CRISPR/Cas genetic circuits that interface host regulatory networks

(2014) A. A. Nielsen et al.   Molecular Systems Biology

Tunable protein degradation in bacteria

(2014) D Ewen Cameron et al.   NATURE BIOTECHNOLOGY

Principles of genetic circuit design

(2014) Jennifer A N Brophy et al.   NATURE METHODS

Permanent genetic memory with >1-byte capacity

(2014) Lei Yang et al.   NATURE METHODS

2-Butanol and Butanone Production in Saccharomyces cerevisiae through Combination of a B12 Dependent Dehydratase and a Secondary Alcohol Dehydrogenase Using a TEV-Based Expression System

(2014) Payam Ghiaci et al.   PLoS One

Protease-based synthetic sensing and signal amplification

(2014) Viktor Stein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensitive detection of proteasomal activation using the Deg-On mammalian synthetic gene circuit

(2014) Wenting Zhao et al.   Nature Communications

Modular Extracellular Sensor Architecture for Engineering Mammalian Cell-based Devices

(2014) Nichole M. Daringer et al.   ACS Synthetic Biology

Synthetic Tunable Amplifying Buffer Circuit in E. coli

(2014) Kayzad Soli Nilgiriwala et al.   ACS Synthetic Biology

A New, Modular Mass Calibrant for High-Mass MALDI-MS

(2013) Simon Weidmann et al.   ANALYTICAL CHEMISTRY

Advances in genetic circuit design: novel biochemistries, deep part mining, and precision gene expression

(2013) Alec AK Nielsen et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Design of orthogonal genetic switches based on a crosstalk map of  s, anti- s, and promoters

(2013) V. A. Rhodius et al.   Molecular Systems Biology

Genomic mining of prokaryotic repressors for orthogonal logic gates

(2013) Brynne C Stanton et al.   Nature Chemical Biology

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

(2013) David Bikard et al.   NUCLEIC ACIDS RESEARCH

Amplifying Genetic Logic Gates

(2013) J. Bonnet et al.   SCIENCE

The N-End Rule Pathway

(2012) Takafumi Tasaki et al.   Annual Review of Biochemistry

Plant Virus Metagenomics: Biodiversity and Ecology

(2012) Marilyn J. Roossinck   Annual Review of Genetics

Post-translational tools expand the scope of synthetic biology

(2012) Evan J Olson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Metabolic engineering of muconic acid production in Saccharomyces cerevisiae

(2012) Kathleen A. Curran et al.   METABOLIC ENGINEERING

Sequestration-based bistability enables tuning of the switching boundaries and design of a latch

(2012) David Chen et al.   Molecular Systems Biology

A regulatory role for repeated decoy transcription factor binding sites in target gene expression

(2012) Tek-Hyung Lee et al.   Molecular Systems Biology

Ribozyme-based insulator parts buffer synthetic circuits from genetic context

(2012) Chunbo Lou et al.   NATURE BIOTECHNOLOGY

Modular control of multiple pathways using engineered orthogonal T7 polymerases

(2012) Karsten Temme et al.   NUCLEIC ACIDS RESEARCH

Rewritable digital data storage in live cells via engineered control of recombination directionality

(2012) J. Bonnet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Refactoring the nitrogen fixation gene cluster from Klebsiella oxytoca

(2012) K. Temme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted protein depletion in Saccharomyces cerevisiae by activation of a bidirectional degron

(2011) Marc Jungbluth et al.   BMC Systems Biology

Substrate Profiling of Tobacco Etch Virus Protease Using a Novel Fluorescence-Assisted Whole-Cell Assay

(2011) George Kostallas et al.   PLoS One

An overview of enzymatic reagents for the removal of affinity tags

(2011) David S. Waugh   PROTEIN EXPRESSION AND PURIFICATION

The N-end rule pathway and regulation by proteolysis

(2011) Alexander Varshavsky   PROTEIN SCIENCE

Activation of Specific Apoptotic Caspases with an Engineered Small-Molecule-Activated Protease

(2010) Daniel C. Gray et al.   CELL

Robust multicellular computing using genetically encoded NOR gates and chemical ‘wires’

(2010) Alvin Tamsir et al.   NATURE

Structural determinants of tobacco vein mottling virus protease substrate specificity

(2010) Ping Sun et al.   PROTEIN SCIENCE

TEV protease-facilitated stoichiometric delivery of multiple genes using a single expression vector

(2010) Xi Chen et al.   PROTEIN SCIENCE

Noise Can Induce Bimodality in Positive Transcriptional Feedback Loops Without Bistability

(2010) T.-L. To et al.   SCIENCE

Efficient protein depletion by genetically controlled deprotection of a dormant N-degron

(2009) Christof Taxis et al.   Molecular Systems Biology

Protein sequestration generates a flexible ultrasensitive response in a genetic network

(2009) Nicolas E Buchler et al.   Molecular Systems Biology

Rapid Modification of Proteins Using a Rapamycin-Inducible Tobacco Etch Virus Protease System

(2009) Damian J. Williams et al.   PLoS One

Cell-Type-Specific TEV Protease Cleavage Reveals Cohesin Functions in Drosophila Neurons

(2008) Andrea Pauli et al.   DEVELOPMENTAL CELL

Tuning the Strength of a Bacterial N-end Rule Degradation Signal

(2008) Kevin H. Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Titration and Ultrasensitivity in Regulatory Networks

(2008) Nicolas E. Buchler et al.   JOURNAL OF MOLECULAR BIOLOGY

A fast, robust and tunable synthetic gene oscillator

(2008) Jesse Stricker et al.   NATURE

Reprogramming of murine and human somatic cells using a single polycistronic vector

(2008) B. W. Carey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three heterologous proteins simultaneously expressed from a chimeric potyvirus: Infectivity, stability and the correlation of genome and virion lengths

(2008) Jani Kelloniemi et al.   VIRUS RESEARCH