Locked and proteolysis-based transcription activator-like effector (TALE) regulation

Split-inteins and their bioapplications

(2015) Yifeng Li   BIOTECHNOLOGY LETTERS

A split-Cas9 architecture for inducible genome editing and transcription modulation

(2015) Bernd Zetsche et al.   NATURE BIOTECHNOLOGY

Designable DNA-binding domains enable construction of logic circuits in mammalian cells

(2014) Rok Gaber et al.   Nature Chemical Biology

Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors

(2014) Jiabiao Hu et al.   NUCLEIC ACIDS RESEARCH

Function-Based Mutation-Resistant Synthetic Signaling Device Activated by HIV-1 Proteolysis

(2014) Andreja Majerle et al.   ACS Synthetic Biology

Revisiting the TALE repeat

(2014) Dong Deng et al.   Protein & Cell

Protein Scaffold-Activated Protein Trans-Splicing in Mammalian Cells

(2013) Daniel F. Selgrade et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biochemical reconstitution of topological DNA binding by the cohesin ring

(2013) Yasuto Murayama et al.   NATURE

Quantitative analysis of TALE–DNA interactions suggests polarity effects

(2013) Joshua F. Meckler et al.   NUCLEIC ACIDS RESEARCH

Two- and three-input TALE-based AND logic computation in embryonic stem cells

(2013) Florian Lienert et al.   NUCLEIC ACIDS RESEARCH

Molecular Dynamics Simulations of DNA-Free and DNA-Bound TAL Effectors

(2013) Hua Wan et al.   PLoS One

Expanding the Boolean Logic of the Prokaryotic Transcription Factor XylR by Functionalization of Permissive Sites with a Protease-Target Sequence

(2013) Belen Calles et al.   ACS Synthetic Biology

A tunable zinc finger-based framework for Boolean logic computation in mammalian cells

(2012) Jason J. Lohmueller et al.   NUCLEIC ACIDS RESEARCH

Engineering split intein DnaE from Nostoc punctiforme for rapid protein purification

(2012) M. Ramirez et al.   PROTEIN ENGINEERING DESIGN & SELECTION

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

(2012) A. N.-S. Mak et al.   SCIENCE

Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

(2012) D. Deng et al.   SCIENCE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression

(2012) Yi Li et al.   Scientific Reports

Photocontrol of Protein Activity Mediated by the Cleavage Reaction of a Split Intein

(2011) Jens Binschik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

(2011) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Intein-mediated Cyclization of Bacterial Acyl Carrier Protein Stabilizes Its Folded Conformation but Does Not Abolish Function

(2010) Gerrit Volkmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The naturally splitNpuDnaE intein exhibits an extraordinarily high rate in the proteintrans-splicing reaction

(2009) Joachim Zettler et al.   FEBS LETTERS

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Rapid Modification of Proteins Using a Rapamycin-Inducible Tobacco Etch Virus Protease System

(2009) Damian J. Williams et al.   PLoS One

Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors

(2009) J. Boch et al.   SCIENCE

A Simple Cipher Governs DNA Recognition by TAL Effectors

(2009) M. J. Moscou et al.   SCIENCE