Amorphous nasal powder advanced performance: in vitro/ex vivo studies and correlation with in vivo pharmacokinetics
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Amorphous nasal powder advanced performance: in vitro/ex vivo studies and correlation with in vivo pharmacokinetics
Authors
Keywords
-
Journal
Journal of Pharmaceutical Investigation
Volume 53, Issue 5, Pages 723-742
Publisher
Springer Science and Business Media LLC
Online
2023-09-18
DOI
10.1007/s40005-023-00630-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Optimising nasal powder drug delivery – Characterisation of the effect of excipients on drug absorption
- (2023) Marie Trenkel et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Improved drug transfer into brain tissue via the “nose-to-brain” approach using suspension or powder formulations based on the amorphous solid dispersion technique
- (2023) Susumu Suwabe et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- In vitro dissolution/permeation tools for amorphous solid dispersions bioavailability forecasting II: Comparison and mechanistic insights
- (2023) Patrícia D. Nunes et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Nasal-PAMPA: A novel non-cell-based high throughput screening assay for prediction of nasal drug permeability
- (2023) Patrícia Henriques et al. International Journal of Pharmaceutics
- Thermosensitive in situ hydrogels of rivastigmine-loaded lipid-based nanosystems for nose-to-brain delivery: characterisation, biocompatibility, and drug deposition studies
- (2022) S. Cunha et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Fluorescence-enabled evaluation of nasal tract deposition and coverage of pharmaceutical formulations in a silicone nasal cast using an innovative spray device
- (2022) Davide D'Angelo et al. Journal of Advanced Research
- Spray dried powders for nasal delivery: Process and formulation considerations
- (2022) Patrícia Henriques et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- In Vitro Regional Deposition of Nasal Sprays in an Idealized Nasal Inlet: Comparison with In Vivo Gamma Scintigraphy
- (2022) John Z. Chen et al. PHARMACEUTICAL RESEARCH
- Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery
- (2022) Susana Farinha et al. PHARMACEUTICAL RESEARCH
- Nasal Powder Formulations: In-Vitro Characterisation of the Impact of Powders on Nasal Residence Time and Sensory Effects
- (2021) Marie Trenkel et al. Pharmaceutics
- Flurbiprofen Sodium Microparticles and Soft Pellets for Nose-to-Brain Delivery: Serum and Brain Levels in Rats after Nasal Insufflation
- (2021) Laura Tiozzo Fasiolo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Nasal powders of quercetin-β-cyclodextrin derivatives complexes with mannitol/lecithin microparticles for Nose-to-Brain delivery: In vitro and ex vivo evaluation
- (2021) Paraskevi Papakyriakopoulou et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The Development of an In Vitro Horizontal Diffusion Cell to Monitor Nasal Powder Penetration Inline
- (2021) Péter Gieszinger et al. Pharmaceutics
- Insights into the Release Mechanisms of ITZ:HPMCAS Amorphous Solid Dispersions: The Role of Drug-Rich Colloids
- (2021) Patrícia D. Nunes et al. MOLECULAR PHARMACEUTICS
- Comparison of Various Cell Lines and Three-Dimensional Mucociliary Tissue Model Systems to Estimate Drug Permeability Using an In Vitro Transport Study to Predict Nasal Drug Absorption in Rats
- (2020) Tomoyuki Furubayashi et al. Pharmaceutics
- In vitro assessment of an idealized nose for nasal spray testing: Comparison with regional deposition in realistic nasal replicas
- (2020) John Z. Chen et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- QbD-driven development of intranasal lipid nanoparticles for depression treatment
- (2020) Carla Vitorino et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Progressing Towards the Sustainable Development of Cream Formulations
- (2020) Ana Simões et al. Pharmaceutics
- Nasal Powder Formulation of Tranexamic Acid and Hyaluronic Acid for the Treatment of Epistaxis
- (2020) Larissa Gomes dos Reis et al. PHARMACEUTICAL RESEARCH
- A combo-strategy to improve brain delivery of antiepileptic drugs: Focus on BCRP and intranasal administration
- (2020) Joana Gonçalves et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Spray-dried nanoparticle-loaded pectin microspheres for dexamethasone nasal delivery
- (2019) Bisera Jurišić Dukovski et al. DRYING TECHNOLOGY
- Anti-inflammatory flurbiprofen nasal powders for nose-to-brain delivery in Alzheimer’s disease
- (2019) Laura Tiozzo Fasiolo et al. JOURNAL OF DRUG TARGETING
- An idealized geometry that mimics average nasal spray deposition in adults: A computational study
- (2019) Milad Kiaee et al. COMPUTERS IN BIOLOGY AND MEDICINE
- Drying droplet as a template for solid formation: A review
- (2019) R. de Souza Lima et al. POWDER TECHNOLOGY
- Spray Dried Formulations for Inhalation—Meaningful Characterisation of Powder Properties
- (2019) Angelika Jüptner et al. Pharmaceutics
- Opportunity and challenges of nasal powders: Drug formulation and delivery
- (2018) Laura Tiozzo Fasiolo et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- In vitro and ex vivo correlation of drug release from ophthalmic ointments
- (2018) Quanying Bao et al. JOURNAL OF CONTROLLED RELEASE
- An overview of in vitro dissolution/release methods for novel mucosal drug delivery systems
- (2018) Mario Jug et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- The Role of Combined Penetration Enhancers in Nasal Microspheres on In Vivo Drug Bioavailability
- (2018) Giovanna Rassu et al. Pharmaceutics
- Searching for physiologically relevant in vitro dissolution techniques for orally inhaled drugs
- (2018) Snezana Radivojev et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Pharmacokinetics of opicapone, a third-generation COMT inhibitor, after single and multiple oral administration: A comparative study in the rat
- (2017) Daniela Gonçalves et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Effect of solubility enhancement on nasal absorption of meloxicam
- (2016) Tamás Horváth et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Application of RPMI 2650 as a cell model to evaluate solid formulations for intranasal delivery of drugs
- (2016) Vanessa S.S. Gonçalves et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Nasal powders of thalidomide for local treatment of nose bleeding in persons affected by hereditary hemorrhagic telangiectasia
- (2016) G. Colombo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- PLGA/DPPC/trimethylchitosan spray-dried microparticles for the nasal delivery of ropinirole hydrochloride: in vitro , ex vivo and cytocompatibility assessment
- (2016) Christina Karavasili et al. Materials Science & Engineering C-Materials for Biological Applications
- Carrier-based dry powder formulation for nasal delivery of vaccines utilizing BSA as model drug
- (2016) Sabrina Trows et al. POWDER TECHNOLOGY
- Nasal chitosan microparticles target a zidovudine prodrug to brain HIV sanctuaries
- (2015) Alessandro Dalpiaz et al. ANTIVIRAL RESEARCH
- Design of salmon calcitonin particles for nasal delivery using spray-drying and novel supercritical fluid-assisted spray-drying processes
- (2015) Wonkyung Cho et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Study of sodium hyaluronate-based intranasal formulations containing micro- or nanosized meloxicam particles
- (2015) Csilla Bartos et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- In vitro–in vivo correlation for complex non-oral drug products: Where do we stand?
- (2015) Jie Shen et al. JOURNAL OF CONTROLLED RELEASE
- Solid microparticles based on chitosan or methyl-β-cyclodextrin: A first formulative approach to increase the nose-to-brain transport of deferoxamine mesylate
- (2015) Giovanna Rassu et al. JOURNAL OF CONTROLLED RELEASE
- Nasal polysaccharides-glucose regulator microparticles: Optimization, tolerability and antidiabetic activity in rats
- (2014) Enas Elmowafy et al. CARBOHYDRATE POLYMERS
- Intranasal administration of carbamazepine to mice: A direct delivery pathway for brain targeting
- (2014) Ana Serralheiro et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Intranasal delivery of systemic-acting drugs: Small-molecules and biomacromolecules
- (2014) Ana Fortuna et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review
- (2014) Alejandro Sosnik et al. PROGRESS IN POLYMER SCIENCE
- Antidiuretic effect of desmopressin chimera agglomerates by nasal administration in rats
- (2012) Anna Giulia Balducci et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Particles and powders: Tools of innovation for non-invasive drug administration
- (2012) Francesca Buttini et al. JOURNAL OF CONTROLLED RELEASE
- Overcoming sink limitations in dissolution testing: a review of traditional methods and the potential utility of biphasic systems
- (2012) Daniel J. Phillips et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride
- (2010) Yeamin Huh et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Crystallization Tendency of Active Pharmaceutical Ingredients Following Rapid Solvent Evaporation—Classification and Comparison with Crystallization Tendency from Under cooled Melts
- (2010) Bernard Van Eerdenbrugh et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Influence of Chitosan Glutamate on the in vivo Intranasal Absorption of Rokitamycin from Microspheres
- (2010) Elisabetta Gavini et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Enhanced Dissolution and Oral Bioavailability of Piroxicam Formulations: Modulating Effect of Phospholipids
- (2010) Sabiruddin Mirza et al. Pharmaceutics
- Nasal administration of metoclopramide from different dosage forms: in vitro, ex vivo, and in vivo evaluation
- (2009) Cetin Tas et al. DRUG DELIVERY
- Development of a Cyclodextrin-Based Nasal Delivery System for Lorazepam
- (2008) Mario Jug et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Brain uptake of an anti-ischemic agent by nasal administration of microparticles
- (2008) Alessandro Dalpiaz et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More