Insights into the Release Mechanisms of ITZ:HPMCAS Amorphous Solid Dispersions: The Role of Drug-Rich Colloids
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Title
Insights into the Release Mechanisms of ITZ:HPMCAS Amorphous Solid Dispersions: The Role of Drug-Rich Colloids
Authors
Keywords
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Journal
MOLECULAR PHARMACEUTICS
Volume 19, Issue 1, Pages 51-66
Publisher
American Chemical Society (ACS)
Online
2021-12-18
DOI
10.1021/acs.molpharmaceut.1c00578
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- (2021) Maria C. Paisana et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
- (2021) D. Dahlgren et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
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- (2021) Tze Ning Hiew et al. MOLECULAR PHARMACEUTICS
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- (2020) Mette Sloth Bohsen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Elucidating Spray Dried Dispersion Dissolution Mechanisms with Focused Beam Reflectance Measurement: Contribution of Polymer Chemistry and Particle Properties to Performance
- (2019) Clare Frances Rawlinson Malone et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Insights into the Dissolution Mechanism of Ritonavir–Copovidone Amorphous Solid Dispersions: Importance of Congruent Release for Enhanced Performance
- (2019) Anura S. Indulkar et al. MOLECULAR PHARMACEUTICS
- Congruent release of drug and polymer: A “sweet spot” in the dissolution of amorphous solid dispersions
- (2019) Sugandha Saboo et al. JOURNAL OF CONTROLLED RELEASE
- Enhancement of mass transfer from particles by local shear‐rate and correlations with application to drug dissolution
- (2019) Yanxing Wang et al. AICHE JOURNAL
- Recent Advances in Understanding the Micro- and Nanoscale Phenomena of Amorphous Solid Dispersions
- (2019) Ralm G. Ricarte et al. MOLECULAR PHARMACEUTICS
- Insights into the Dissolution Behavior of Ledipasvir–Copovidone Amorphous Solid Dispersions: Role of Drug Loading and Intermolecular Interactions
- (2019) Chailu Que et al. MOLECULAR PHARMACEUTICS
- Mechanisms of increased bioavailability through amorphous solid dispersions: a review
- (2019) Andreas Schittny et al. DRUG DELIVERY
- A high-sensitivity HPLC-ELSD method for HPMC-AS quantification and its application in elucidating the release mechanism of HPMC-AS based amorphous solid dispersions
- (2018) Shan Wang et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Mechanistic understanding of the phase behavior of supersaturated solutions of poorly water-soluble drugs
- (2018) Francesco Tres et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery – An update
- (2018) Scott V. Jermain et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Mesoporous systems for poorly soluble drugs – recent trends
- (2018) Joakim Riikonen et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Tailoring supersaturation from amorphous solid dispersions
- (2018) Na Li et al. JOURNAL OF CONTROLLED RELEASE
- Enhanced Dissolution of a Porous Carrier–Containing Ternary Amorphous Solid Dispersion System Prepared by a Hot Melt Method
- (2018) Masataka Hanada et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Developing Quantitative In Vitro – In Vivo Correlation for Fenofibrate Immediate-Release Formulations With the Biphasic Dissolution-Partition Test Method
- (2018) Hao Xu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Approaches to increase mechanistic understanding and aid in the selection of precipitation inhibitors for supersaturating formulations - a PEARRL review
- (2018) Daniel J. Price et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Qualitative and Quantitative Characterization of Composition Heterogeneity on the Surface of Spray Dried Amorphous Solid Dispersion Particles by an Advanced Surface Analysis Platform with High Surface Sensitivity and Superior Spatial Resolution
- (2018) Sonal V. Bhujbal et al. MOLECULAR PHARMACEUTICS
- Investigation of Polymer/Surfactant Interactions and Their Impact on Itraconazole Solubility and Precipitation Kinetics for Developing Spray-Dried Amorphous Solid Dispersions
- (2018) Tanvi M. Deshpande et al. MOLECULAR PHARMACEUTICS
- Analysis of the Literature and Patents on Solid Dispersions from 1980 to 2015
- (2018) Jinglu Zhang et al. MOLECULES
- Lipophilicity and hydrophobicity considerations in bio-enabling oral formulations approaches - a PEARRL review
- (2018) Felix Ditzinger et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Spray drying of pharmaceuticals and biopharmaceuticals: Critical parameters and experimental process optimization approaches
- (2018) Ahmad Ziaee et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Mechanistic Study of Belinostat Oral Absorption From Spray-Dried Dispersions
- (2018) Aaron Stewart et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Dynamic dissolution-/permeation-testing of nano- and microparticle formulations of fenofibrate
- (2017) Daniel Sironi et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- BCS class IV drugs: Highly notorious candidates for formulation development
- (2017) Rohan Ghadi et al. JOURNAL OF CONTROLLED RELEASE
- Methods for the preparation of amorphous solid dispersions – A comparative study
- (2017) Michal Beneš et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
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- (2017) Aaron M. Stewart et al. MOLECULAR PHARMACEUTICS
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- (2017) Hitesh S. Purohit et al. PHARMACEUTICAL RESEARCH
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- (2016) Lynne S. Taylor et al. ADVANCED DRUG DELIVERY REVIEWS
- Oral bioavailability enhancement through supersaturation: an update and meta-analysis
- (2016) Sophia Yui Kau Fong et al. Expert Opinion on Drug Delivery
- Exploiting the Phenomenon of Liquid–Liquid Phase Separation for Enhanced and Sustained Membrane Transport of a Poorly Water-Soluble Drug
- (2016) Anura S. Indulkar et al. MOLECULAR PHARMACEUTICS
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