Kinetics and Molecular Docking Study of an Anti-diabetic Drug Glimepiride as Acetylcholinesterase Inhibitor: Implication for Alzheimer’s Disease-Diabetes Dual Therapy

Alzheimer’s disease and type 2 diabetes via chronic inflammatory mechanisms

(2015) Gohar Mushtaq et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Invokana (Canagliflozin) as a Dual Inhibitor of Acetylcholinesterase and Sodium Glucose Co-Transporter 2: Advancement in Alzheimer’s Disease- Diabetes Type 2 Linkage via an Enzoinformatics Study

(2014) Syed Rizvi et al.   CNS & Neurological Disorders-Drug Targets

Prediction of Comparative Inhibition Efficiency for a Novel Natural Ligand, Galangin Against Human Brain Acetylcholinesterase, Butyrylcholinesterase and 5-Lipoxygenase: A Neuroinformatics Study

(2014) Sibhghatulla Shaikh et al.   CNS & Neurological Disorders-Drug Targets

Molecular Interaction of Human Brain Acetylcholinesterase with a Natural Inhibitor Huperzine-B: An Enzoinformatics Approach

(2014) Aftab Alam et al.   CNS & Neurological Disorders-Drug Targets

Repurposing Diabetes Drugs for Brain Insulin Resistance in Alzheimer Disease

(2014) M. Yarchoan et al.   DIABETES

Type 2 Diabetes and Antidiabetic Medications in Relation to Dementia Diagnosis

(2014) Chin Cheng et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Glimepiride attenuates Aβ production via suppressing BACE1 activity in cortical neurons

(2013) Feiyang Liu et al.   NEUROSCIENCE LETTERS

Alzheimer’s Disease And Type 2 Diabetes: Exploring The Association To Obesity And Tyrosine Hydroxylase

(2012) Medha Priyadarshini et al.   CNS & Neurological Disorders-Drug Targets

An update on type 2 diabetes, vascular dementia and Alzheimer's disease

(2012) L.G. Exalto et al.   EXPERIMENTAL GERONTOLOGY

Saffron as a Source of Novel Acetylcholinesterase Inhibitors: Molecular Docking and in Vitro Enzymatic Studies

(2012) George D. Geromichalos et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Improvement in long term and visuo-spatial memory following chronic pioglitazone in mouse model of Alzheimer's disease

(2012) Rachna Gupta et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Impact and Therapeutic Potential of PPARs in Alzheimers Disease

(2011) Michael T. Heneka et al.   Current Neuropharmacology

A Common Pathogenic Mechanism Linking Type-2 Diabetes and Alzheimer's Disease: Evidence from Animal Models

(2011) Sun Ah Park   Journal of Clinical Neurology

Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

(2011) Rafael León et al.   MEDICINAL RESEARCH REVIEWS

Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?

(2010) Kawser Akter et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Alzheimer's disease: strategies for disease modification

(2010) Martin Citron   NATURE REVIEWS DRUG DISCOVERY

Drug development for Alzheimer's disease: Where are we now and where are we headed?

(2009) Marwan N. Sabbagh   American Journal Geriatric Pharmacotherapy

Cognitive decline associated with dementia and type 2 diabetes: the interplay of risk factors

(2009) C. Messier et al.   DIABETOLOGIA

Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease

(2009) Tomohiko Sato et al.   NEUROBIOLOGY OF AGING

Flexibility of Aromatic Residues in the Active-Site Gorge of Acetylcholinesterase: X-ray versus Molecular Dynamics

(2008) Yechun Xu et al.   BIOPHYSICAL JOURNAL

Multi-target-Directed Ligands To Combat Neurodegenerative Diseases

(2008) Andrea Cavalli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cognition and diabetes: a lifespan perspective

(2008) Geert Jan Biessels et al.   LANCET NEUROLOGY

Central obesity and increased risk of dementia more than three decades later

(2008) R. A. Whitmer et al.   NEUROLOGY