- Home
- Publications
- Publication Search
- Publication Details
Title
Pediatric low-grade gliomas: implications of the biologic era
Authors
Keywords
-
Journal
NEURO-ONCOLOGY
Volume -, Issue -, Pages now209
Publisher
Oxford University Press (OUP)
Online
2016-09-29
DOI
10.1093/neuonc/now209
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors
- (2016) Barbara Rivera et al. ACTA NEUROPATHOLOGICA
- Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology
- (2016) Ibrahim Qaddoumi et al. ACTA NEUROPATHOLOGICA
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Nonrandomized comparison of neurofibromatosis type 1 and non-neurofibromatosis type 1 children who received carboplatin and vincristine for progressive low-grade glioma: A report from the Children's Oncology Group
- (2016) Joann L. Ater et al. CANCER
- Clinical and treatment factors determining long-term outcomes for adult survivors of childhood low-grade glioma: A population-based study
- (2016) Rahul Krishnatry et al. CANCER
- Successful Treatment of a ProgressiveBRAFV600E–Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy
- (2016) Eudocia Q. Lee et al. JOURNAL OF CLINICAL ONCOLOGY
- Disseminated glioneuronal tumors occurring in childhood: treatment outcomes and BRAF alterations including V600E mutation
- (2016) Andrew J. Dodgshun et al. JOURNAL OF NEURO-ONCOLOGY
- MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism
- (2016) Pratiti Bandopadhayay et al. NATURE GENETICS
- Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
- (2016) N. McGranahan et al. SCIENCE
- Pilocytic astrocytoma: pathology, molecular mechanisms and markers
- (2015) V. Peter Collins et al. ACTA NEUROPATHOLOGICA
- Reproducibility of Retinal Nerve Fiber Layer Thickness Measures Using Eye Tracking in Children With Nonglaucomatous Optic Neuropathy
- (2015) Raneem D. Rajjoub et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Longitudinal Change of Circumpapillary Retinal Nerve Fiber Layer Thickness in Children With Optic Pathway Gliomas
- (2015) Robert A. Avery et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction
- (2015) Sagar Uttarkar et al. BLOOD
- BRAFMutation andCDKN2ADeletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma
- (2015) Matthew Mistry et al. JOURNAL OF CLINICAL ONCOLOGY
- KIAA1549
- (2015) Aline Paixão Becker et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial
- (2015) Georgina V Long et al. LANCET
- Next-generation (epi)genetic drivers of childhood brain tumours and the outlook for targeted therapies
- (2015) Paul A Northcott et al. LANCET ONCOLOGY
- Combined Pan-RAF and MEK Inhibition Overcomes Multiple Resistance Mechanisms to Selective RAF Inhibitors
- (2015) S. R. Whittaker et al. MOLECULAR CANCER THERAPEUTICS
- A pilot study using carboplatin, vincristine, and temozolomide in children with progressive/symptomatic low-grade glioma: a Children's Oncology Group study
- (2015) Murali Chintagumpala et al. NEURO-ONCOLOGY
- EGFR blockade prevents glioma escape from BRAFV600E targeted therapy
- (2015) Tsun-Wen Yao et al. Oncotarget
- International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading
- (2014) David N. Louis et al. BRAIN PATHOLOGY
- The Cyclic AMP Pathway Is a Sex-Specific Modifier of Glioma Risk in Type I Neurofibromatosis Patients
- (2014) N. M. Warrington et al. CANCER RESEARCH
- Induction of Robust Type-I CD8+ T-cell Responses in WHO Grade 2 Low-Grade Glioma Patients Receiving Peptide-Based Vaccines in Combination with Poly-ICLC
- (2014) H. Okada et al. CLINICAL CANCER RESEARCH
- Patient Reported Endpoints for Measuring Clinical Benefit in (High Grade Glioma) Primary Brain Tumor Patients
- (2014) Terri S. Armstrong et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development
- (2014) Efrain Sanchez-Ortiz et al. GENES & DEVELOPMENT
- A vaccine targeting mutant IDH1 induces antitumour immunity
- (2014) Theresa Schumacher et al. NATURE
- The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
- (2014) Gang Wu et al. NATURE GENETICS
- Microglia in the tumor microenvironment: taking their TOLL on glioma biology
- (2014) D. H. Gutmann NEURO-ONCOLOGY
- Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas
- (2014) M. A. Karajannis et al. NEURO-ONCOLOGY
- Long-term outcome of 4,040 children diagnosed with pediatric low-grade gliomas: An analysis of the Surveillance Epidemiology and End Results (SEER) database
- (2014) Pratiti Bandopadhayay et al. PEDIATRIC BLOOD & CANCER
- Autophagy Inhibition Improves Chemosensitivity in BRAFV600E Brain Tumors
- (2014) J. M. M. Levy et al. Cancer Discovery
- Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1
- (2014) Edward Kim et al. eLife
- Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma
- (2013) Sally R. Lambert et al. ACTA NEUROPATHOLOGICA
- New Strategies in Pediatric Gliomas: Molecular Advances in Pediatric Low-Grade Gliomas as a Model
- (2013) E. Raabe et al. CLINICAL CANCER RESEARCH
- Brainstem Ganglioglioma Successfully Treated With Vemurafenib
- (2013) Sarah Rush et al. JOURNAL OF CLINICAL ONCOLOGY
- Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
- (2013) David T W Jones et al. NATURE GENETICS
- Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
- (2013) NATURE GENETICS
- Fractional anisotropy of the optic radiations is associated with visual acuity loss in optic pathway gliomas of neurofibromatosis type 1
- (2013) P. M. K. de Blank et al. NEURO-ONCOLOGY
- Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas—a Pediatric Brain Tumor Consortium study
- (2013) Sridharan Gururangan et al. NEURO-ONCOLOGY
- Challenges with defining response to antitumor agents in pediatric neuro-oncology: A report from the response assessment in pediatric neuro-oncology (RAPNO) working group
- (2013) Katherine E. Warren et al. PEDIATRIC BLOOD & CANCER
- Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1
- (2013) L. A. Ramkissoon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
- (2013) D. Rohle et al. SCIENCE
- Marked Recovery of Vision in Children With Optic Pathway Gliomas Treated With Bevacizumab
- (2013) Robert A. Avery et al. JAMA Ophthalmology
- Innate Neural Stem Cell Heterogeneity Determines the Patterning of Glioma Formation in Children
- (2012) Da Yong Lee et al. CANCER CELL
- ERK Inhibition Rescues Defects in Fate Specification of Nf1-Deficient Neural Progenitors and Brain Abnormalities
- (2012) Yuan Wang et al. CELL
- Molecular Pathways: Fibroblast Growth Factor Signaling: A New Therapeutic Opportunity in Cancer
- (2012) A. N. Brooks et al. CLINICAL CANCER RESEARCH
- Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner
- (2012) A. Kaul et al. GENES & DEVELOPMENT
- Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma
- (2012) D. H. Gutmann et al. GENOME RESEARCH
- Phase II Study of Weekly Vinblastine in Recurrent or Refractory Pediatric Low-Grade Glioma
- (2012) Eric Bouffet et al. JOURNAL OF CLINICAL ONCOLOGY
- Randomized Study of Two Chemotherapy Regimens for Treatment of Low-Grade Glioma in Young Children: A Report From the Children's Oncology Group
- (2012) Joann L. Ater et al. JOURNAL OF CLINICAL ONCOLOGY
- Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
- (2012) Axel Hauschild et al. LANCET
- PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome
- (2012) S. Mueller et al. NEURO-ONCOLOGY
- Long-term follow-up of the multicenter, multidisciplinary treatment study HIT-LGG-1996 for low-grade glioma in children and adolescents of the German Speaking Society of Pediatric Oncology and Hematology
- (2012) A. K. Gnekow et al. NEURO-ONCOLOGY
- Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis
- (2012) M. J. Fisher et al. NEURO-ONCOLOGY
- Long-term efficacy and toxicity of bevacizumab-based therapy in children with recurrent low-grade gliomas
- (2012) Eugene I. Hwang et al. PEDIATRIC BLOOD & CANCER
- A feasibility and efficacy study of rapamycin and erlotinib for recurrent pediatric low-grade glioma (LGG)
- (2012) Michal Yalon et al. PEDIATRIC BLOOD & CANCER
- Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma
- (2012) D. Singh et al. SCIENCE
- Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma
- (2011) Huriye Cin et al. ACTA NEUROPATHOLOGICA
- Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
- (2011) Genevieve Schindler et al. ACTA NEUROPATHOLOGICA
- Pseudoprogression and Pseudoresponse: Imaging Challenges in the Assessment of Posttreatment Glioma
- (2011) L.C. Hygino da Cruz et al. AMERICAN JOURNAL OF NEURORADIOLOGY
- MAPK pathway activation in pilocytic astrocytoma
- (2011) David T. W. Jones et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Genetic Aberrations Leading to MAPK Pathway Activation Mediate Oncogene-Induced Senescence in Sporadic Pilocytic Astrocytomas
- (2011) K. Jacob et al. CLINICAL CANCER RESEARCH
- BRAF Activation Induces Transformation and Then Senescence in Human Neural Stem Cells: A Pilocytic Astrocytoma Model
- (2011) E. H. Raabe et al. CLINICAL CANCER RESEARCH
- Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas
- (2011) MJ van den Bent et al. LANCET ONCOLOGY
- Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy
- (2011) X. Gong et al. NEUROLOGY
- Favorable outcome with conservative treatment for children with low grade brainstem tumors
- (2011) Iris Fried et al. PEDIATRIC BLOOD & CANCER
- BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications
- (2011) Dora Dias-Santagata et al. PLoS One
- MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas
- (2010) Ruth G. Tatevossian et al. ACTA NEUROPATHOLOGICA
- Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician’s perspective
- (2010) Martin J. van den Bent ACTA NEUROPATHOLOGICA
- Birth incidence and prevalence of tumor-prone syndromes: Estimates from a UK family genetic register service
- (2010) D.G. Evans et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Phase I Trial of Lenalidomide in Pediatric Patients With Recurrent, Refractory, or Progressive Primary CNS Tumors: Pediatric Brain Tumor Consortium Study PBTC-018
- (2010) Katherine E. Warren et al. JOURNAL OF CLINICAL ONCOLOGY
- Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas
- (2010) Margaret J. Dougherty et al. NEURO-ONCOLOGY
- Preclinical Cancer Therapy in a Mouse Model of Neurofibromatosis-1 Optic Glioma
- (2008) B. Hegedus et al. CANCER RESEARCH
- Tandem Duplication Producing a Novel OncogenicBRAFFusion Gene Defines the Majority of Pilocytic Astrocytomas
- (2008) David T.W. Jones et al. CANCER RESEARCH
- BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas
- (2008) Stefan Pfister et al. JOURNAL OF CLINICAL INVESTIGATION
- Gliomas in Neurofibromatosis Type 1: A Clinicopathologic Study of 100 Patients
- (2008) Fausto J. Rodriguez et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started