Pilocytic astrocytoma: pathology, molecular mechanisms and markers

International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading

(2014) David N. Louis et al.   BRAIN PATHOLOGY

FGFR1Mutations in Rosette-Forming Glioneuronal Tumors of the Fourth Ventricle

(2014) Marco Gessi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

(2014) Gang Wu et al.   NATURE GENETICS

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011

(2014) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma

(2013) Sally R. Lambert et al.   ACTA NEUROPATHOLOGICA

Epithelioid GBMs Show a High Percentage of BRAF V600E Mutation

(2013) Bette Kay Kleinschmidt-DeMasters et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Dysembryoplastic Neuroepithelial Tumors Share with Pleomorphic Xanthoastrocytomas and Gangliogliomas BRAFV600EMutation and Expression

(2013) Céline Chappé et al.   BRAIN PATHOLOGY

Noonan syndrome

(2013) Amy E Roberts et al.   LANCET

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

(2013) David T W Jones et al.   NATURE GENETICS

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

(2013)   NATURE GENETICS

Tumor adaptation and resistance to RAF inhibitors

(2013) Piro Lito et al.   NATURE MEDICINE

Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas

(2013) A. J. Sievert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KIAA1549-BRAFFusions and IDH Mutations Can Coexist in Diffuse Gliomas of Adults

(2012) Manuela Badiali et al.   BRAIN PATHOLOGY

Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma

(2012) D. H. Gutmann et al.   GENOME RESEARCH

BRAF Alterations Are Frequent in Cerebellar Low-Grade Astrocytomas With Diffuse Growth Pattern

(2012) Cristiane M. Ida et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Outcome analysis of childhood pilocytic astrocytomas: a retrospective study of 148 cases at a single institution

(2012) C. Colin et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

(2012) D. Singh et al.   SCIENCE

Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

(2011) Huriye Cin et al.   ACTA NEUROPATHOLOGICA

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody

(2011) David Capper et al.   ACTA NEUROPATHOLOGICA

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

(2011) Genevieve Schindler et al.   ACTA NEUROPATHOLOGICA

Identification of transcriptional regulatory networks specific to pilocytic astrocytoma

(2011) Hrishikesh Deshmukh et al.   BMC Medical Genomics

A molecular analysis of individuals with neurofibromatosis type 1 (NF1) and optic pathway gliomas (OPGs), and an assessment of genotype-phenotype correlations

(2011) S. Sharif et al.   JOURNAL OF MEDICAL GENETICS

Preclincial testing of Sorafenib and RAD001 in the Nfflox/flox;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging

(2011) Jianqiang Wu et al.   PEDIATRIC BLOOD & CANCER

Spectrum of Pilomyxoid Astrocytomas

(2010) Michael W. Johnson et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Anaplasia in Pilocytic Astrocytoma Predicts Aggressive Behavior

(2010) Fausto J. Rodriguez et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Oncogenic BRAF Mutation with CDKN2A Inactivation Is Characteristic of a Subset of Pediatric Malignant Astrocytomas

(2010) J. D. Schiffman et al.   CANCER RESEARCH

Pilocytic astrocytoma of the optic pathway: a tumour deriving from radial glia cells with a specific gene signature

(2009) A. Tchoghandjian et al.   BRAIN

Duplication of 7q34 in Pediatric Low-Grade Astrocytomas Detected by High-Density Single-Nucleotide Polymorphism-Based Genotype Arrays Results in a NovelBRAFFusion Gene

(2009) Angela J. Sievert et al.   BRAIN PATHOLOGY

Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

(2009) K Jacob et al.   BRITISH JOURNAL OF CANCER

Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas

(2009) Tim Forshew et al.   JOURNAL OF PATHOLOGY

Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

(2009) D T W Jones et al.   ONCOGENE

Tandem Duplication Producing a Novel OncogenicBRAFFusion Gene Defines the Majority of Pilocytic Astrocytomas

(2008) David T.W. Jones et al.   CANCER RESEARCH

The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders

(2008) Yoko Aoki et al.   HUMAN MUTATION

Prognosis and Treatment of Spinal Cord Astrocytoma

(2008) Kiernan J. Minehan et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

(2008) Stefan Pfister et al.   JOURNAL OF CLINICAL INVESTIGATION

Gliomas in Neurofibromatosis Type 1: A Clinicopathologic Study of 100 Patients

(2008) Fausto J. Rodriguez et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Frequent Gains at Chromosome 7q34 Involving BRAF in Pilocytic Astrocytoma

(2008) Eli E. Bar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Rate of spontaneous hemorrhage in histologically proven cases of pilocytic astrocytoma

(2008) J. Bradley White et al.   JOURNAL OF NEUROSURGERY