Regulatory T cells in immune-mediated renal disease

Regulatory T-cells in autoimmune diseases: Challenges, controversies and—yet—unanswered questions

(2015) Charlotte R. Grant et al.   AUTOIMMUNITY REVIEWS

Regulatory T cells-derived IL-35 promotes the growth of adult acute myeloid leukemia blasts

(2015) Qianshan Tao et al.   INTERNATIONAL JOURNAL OF CANCER

Endogenous Toll-Like Receptor 9 Regulates AKI by Promoting Regulatory T Cell Recruitment

(2015) M. A. Alikhan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal participation of myeloperoxidase in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis

(2015) Kim M. O’Sullivan et al.   KIDNEY INTERNATIONAL

Protective effect of CD4+CD25highCD127low regulatory T cells in renal ischemia–reperfusion injury

(2014) Cao Jun et al.   CELLULAR IMMUNOLOGY

Human CD4+CD25+Foxp3+ Regulatory T Cells Do Not Constitutively Express IL-35

(2014) E. Bardel et al.   JOURNAL OF IMMUNOLOGY

Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA Methylation

(2014) G. Lal et al.   JOURNAL OF IMMUNOLOGY

Regulatory CD4+ T Cells Promote B Cell Anergy in Murine Lupus

(2014) Y. Liu et al.   JOURNAL OF IMMUNOLOGY

Both PD-1 Ligands Protect the Kidney from Ischemia Reperfusion Injury

(2014) Katarzyna Jaworska et al.   JOURNAL OF IMMUNOLOGY

Ex Vivo–Expanded but Not In Vitro–Induced Human Regulatory T Cells Are Candidates for Cell Therapy in Autoimmune Diseases Thanks to Stable Demethylation of the FOXP3 Regulatory T Cell–Specific Demethylated Region

(2014) Maura Rossetti et al.   JOURNAL OF IMMUNOLOGY

Stat3 Programs Th17-Specific Regulatory T Cells to Control GN

(2014) M. A. Kluger et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

(2014) L. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis

(2014) Junichi Hirahashi et al.   Scientific Reports

Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation

(2013) A. L. Putnam et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Have Defective Treg Cell Function Exacerbated by the Presence of a Suppression-Resistant Effector Cell Population

(2013) Meghan E. Free et al.   ARTHRITIS AND RHEUMATISM

Bee Venom Mitigates Cisplatin-Induced Nephrotoxicity by Regulating CD4+CD25+Foxp3+Regulatory T Cells in Mice

(2013) Hyunseong Kim et al.   Evidence-based Complementary and Alternative Medicine

Thymic Deletion and Regulatory T Cells Prevent Antimyeloperoxidase GN

(2013) D. S. Y. Tan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulatory T Cell-Derived IL-10 Ameliorates Crescentic GN

(2013) A. Ostmann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IL-2/Anti-IL-2 Complex Attenuates Renal Ischemia-Reperfusion Injury through Expansion of Regulatory T Cells

(2013) M.-G. Kim et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mesenchymal stem cells attenuate ischemic acute kidney injury by inducing regulatory T cells through splenocyte interactions

(2013) Jie Hu et al.   KIDNEY INTERNATIONAL

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

(2013) Noriko Komatsu et al.   NATURE MEDICINE

CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice

(2013) Olivia Weigert et al.   ARTHRITIS RESEARCH & THERAPY

Regulatory T cells participate in CD39-mediated protection from renal injury

(2012) Yuan Min Wang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Naturally occurring regulatory T cells: markers, mechanisms, and manipulation

(2012) Klaus G. Schmetterer et al.   FASEB JOURNAL

Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ T regulatory cell subpopulations

(2012) C. Scotta et al.   HAEMATOLOGICA

IL-2/IL-2Ab Complexes Induce Regulatory T Cell Expansion and Protect against Proteinuric CKD

(2012) T. Polhill et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Instability of Foxp3 Expression Limits the Ability of Induced Regulatory T Cells to Mitigate Graft versus Host Disease

(2011) A. Beres et al.   CLINICAL CANCER RESEARCH

Regulatory T cells control the Th1 immune response in murine crescentic glomerulonephritis

(2011) Hans-Joachim Paust et al.   KIDNEY INTERNATIONAL

Endogenous foxp3+ T-regulatory cells suppress anti-glomerular basement membrane nephritis

(2011) Joshua D. Ooi et al.   KIDNEY INTERNATIONAL

Pharmacologic recruitment of regulatory T cells as a therapy for ischemic acute kidney injury

(2011) Li-Wen Lai et al.   KIDNEY INTERNATIONAL

Retinoic Acid and Rapamycin Differentially Affect and Synergistically Promote the Ex Vivo Expansion of Natural Human T Regulatory Cells

(2011) Tatiana N. Golovina et al.   PLoS One

Decreased Numbers of Blood Dendritic Cells and Defective Function of Regulatory T Cells in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

(2011) Marie Rimbert et al.   PLoS One

All-Trans Retinoic Acid Promotes TGF-β-Induced Tregs via Histone Modification but Not DNA Demethylation on Foxp3 Gene Locus

(2011) Ling Lu et al.   PLoS One

Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis

(2011) Qian Xing et al.   RHEUMATOLOGY INTERNATIONAL

TGF-β: the sword, the wand, and the shield of FOXP3+ regulatory T cells

(2011) Dat Q. Tran   Journal of Molecular Cell Biology

Regulation of myeloperoxidase-specific T cell responses during disease remission in antineutrophil cytoplasmic antibody-associated vasculitis: The role of Treg cells and tryptophan degradation

(2010) Konstantia-Maria Chavele et al.   ARTHRITIS AND RHEUMATISM

Interstitial Foxp3-positive T cells may predict renal survival in patients with myeroperoxidase anti-neutrophil cytoplasmic antibody-associated glomerulonephritis

(2010) Junko Yoshimura et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Patients with Wegener’s granulomatosis demonstrate a relative deficiency and functional impairment of T-regulatory cells

(2010) Matthew D. Morgan et al.   IMMUNOLOGY

CCR6 Recruits Regulatory T Cells and Th17 Cells to the Kidney in Glomerulonephritis

(2010) J. E. Turner et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Th17-Defining Transcription Factor ROR t Promotes Glomerulonephritis

(2010) O. M. Steinmetz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CD4+CD25+ regulatory T cells attenuate cisplatin-induced nephrotoxicity in mice

(2010) Hyojung Lee et al.   KIDNEY INTERNATIONAL

CD4 + CD25 + regulatory T cells partially mediate the beneficial effects of FTY720, a sphingosine-1-phosphate analogue, during ischaemia/reperfusion-induced acute kidney injury

(2010) M.-G. Kim et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Mycophenolate mofetil modifies kidney tubular injury and Foxp3+ regulatory T cell trafficking during recovery from experimental ischemia–reperfusion

(2010) Maria Teresa Gandolfo et al.   TRANSPLANT IMMUNOLOGY

Aire

(2009) Diane Mathis et al.   Annual Review of Immunology

Th17 and natural Treg cell population dynamics in systemic lupus erythematosus

(2009) Ji Yang et al.   ARTHRITIS AND RHEUMATISM

Epigenetic mechanisms of regulation of Foxp3 expression

(2009) G. Lal et al.   BLOOD

Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFβ gene variants

(2009) Marta Barreto et al.   BMC IMMUNOLOGY

Modulation of p38 MAPK Activity in Regulatory T Cells after Tolerance with Anti-DNA Ig Peptide in (NZB x NZW)F1 Lupus Mice

(2009) E. V. Lourenco et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Regulatory T Cells Directly Suppress B Cells in Systemic Lupus Erythematosus

(2009) N. Iikuni et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cell Suppression Is Potentiated by Target T Cells in a Cell Contact, IL-35- and IL-10-Dependent Manner

(2009) Lauren W. Collison et al.   JOURNAL OF IMMUNOLOGY

The IL-23/Th17 Axis Contributes to Renal Injury in Experimental Glomerulonephritis

(2009) H.-J. Paust et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulatory T Cells Suppress Innate Immunity in Kidney Ischemia-Reperfusion Injury

(2009) G. R. Kinsey et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury

(2009) Maria Teresa Gandolfo et al.   KIDNEY INTERNATIONAL

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

T regulatory cell function in idiopathic minimal lesion nephrotic syndrome

(2009) Carlos Araya et al.   PEDIATRIC NEPHROLOGY

Suppression of Glomerulonephritis in NZB/NZW Lupus Prone Mice by Adoptive Transfer of Ex Vivo Expanded Regulatory T Cells

(2009) Kenneth J. Scalapino et al.   PLoS One

Urinary FOXP3 mRNA in patients with lupus nephritis--relation with disease activity and treatment response

(2009) G. Wang et al.   RHEUMATOLOGY

A role for regulatory T cells in renal acute kidney injury

(2009) Rebecca M.M. Monteiro et al.   TRANSPLANT IMMUNOLOGY

The effect of murine anti-thymocyte globulin on experimental kidney warm ischemia–reperfusion injury in mice

(2009) Hye Ryoun Jang et al.   TRANSPLANT IMMUNOLOGY

Increased Foxp3+ CD4+ Regulatory T Cells with Intact Suppressive Activity but Altered Cellular Localization in Murine Lupus

(2008) Jun Abe et al.   AMERICAN JOURNAL OF PATHOLOGY

Natural regulatory T cells: number and function are normal in the majority of patients with lupus nephritis

(2008) J. Yates et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery

(2008) Tomoki Ito et al.   IMMUNITY

Induction of T Regulatory Cells Attenuates Idiopathic Nephrotic Syndrome

(2008) L. Le Berre et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE