Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation
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Title
Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation
Authors
Keywords
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Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 23, Issue 3, Pages 217-224
Publisher
Springer Nature
Online
2016-02-09
DOI
10.1038/nsmb.3170
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Note: Only part of the references are listed.- CTFFIND4: Fast and accurate defocus estimation from electron micrographs
- (2015) Alexis Rohou et al. JOURNAL OF STRUCTURAL BIOLOGY
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- Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement
- (2015) Tatjana Petojevic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2014) Stefan A. Samel et al. GENES & DEVELOPMENT
- A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome
- (2014) Aline C. Simon et al. NATURE
- SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information
- (2014) Marco Biasini et al. NUCLEIC ACIDS RESEARCH
- Structure of the Yeast Mitochondrial Large Ribosomal Subunit
- (2014) A. Amunts et al. SCIENCE
- A conserved MCM single-stranded DNA binding element is essential for replication initiation
- (2014) Clifford A Froelich et al. eLife
- Structure and evolutionary origins of the CMG complex
- (2013) Silvia Onesti et al. CHROMOSOMA
- Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM
- (2013) Xueming Li et al. NATURE METHODS
- Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA
- (2013) Jingchuan Sun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Towards automated crystallographic structure refinement withphenix.refine
- (2012) Pavel V. Afonine et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The CMG (CDC45/RecJ, MCM, GINS) complex is a conserved component of the DNA replication system in all archaea and eukaryotes
- (2012) Kira S Makarova et al. Biology Direct
- The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation
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- Efficient coupling of ATP hydrolysis to translocation by RecQ helicase
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- ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote
- (2012) Artem Y. Lyubimov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cdc45: the missing RecJ ortholog in eukaryotes?
- (2011) Luis Sanchez-Pulido et al. BIOINFORMATICS
- Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase
- (2011) Yu V. Fu et al. CELL
- The nuts and bolts of ring-translocase structure and mechanism
- (2011) Artem Y Lyubimov et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Structural and Functional Insights into the DNA Replication Factor Cdc45 Reveal an Evolutionary Relationship to the DHH Family of Phosphoesterases
- (2011) Ivet Krastanova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The structural basis for MCM2–7 helicase activation by GINS and Cdc45
- (2011) Alessandro Costa et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- How a DNA Polymerase Clamp Loader Opens a Sliding Clamp
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- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Structure of RecJ Exonuclease Defines Its Specificity for Single-stranded DNA
- (2010) Taisuke Wakamatsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization and Structure Determination of the Cdt1 Binding Domain of Human Minichromosome Maintenance (Mcm) 6
- (2010) Zhun Wei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA Replication: Making Two Forks from One Prereplication Complex
- (2010) Michael Botchan et al. MOLECULAR CELL
- Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins
- (2010) Ivar Ilves et al. MOLECULAR CELL
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing
- (2009) Dirk Remus et al. CELL
- The Mechanism of ATP-Dependent Primer-Template Recognition by a Clamp Loader Complex
- (2009) Kyle R. Simonetta et al. CELL
- The Mcm Complex: Unwinding the Mechanism of a Replicative Helicase
- (2009) M. L. Bochman et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication
- (2009) C. Evrin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal structure of a near-full-length archaeal MCM: Functional insights for an AAA+ hexameric helicase
- (2008) A. S. Brewster et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glycosyltransferases: Structures, Functions, and Mechanisms
- (2007) L.L. Lairson et al. Annual Review of Biochemistry
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