Human BRCA1–BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection

Deciphering the BRCA1 Tumor Suppressor Network

(2015) Qinqin Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous Recombination

(2015) Petr Cejka   JOURNAL OF BIOLOGICAL CHEMISTRY

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection

(2015) Vera Boersma et al.   NATURE

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

(2015) Guotai Xu et al.   NATURE

PTIP associates with Artemis to dictate DNA repair pathway choice

(2014) Jiadong Wang et al.   GENES & DEVELOPMENT

BRCA1 Is a Histone-H2A-Specific Ubiquitin Ligase

(2014) Reinhard Kalb et al.   Cell Reports

BRCA1 Accelerates CtIP-Mediated DNA-End Resection

(2014) Andrés Cruz-García et al.   Cell Reports

RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination

(2013) Meredith B. Metzger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The ATP-dependent Chromatin Remodeling Enzyme Fun30 Represses Transcription by Sliding Promoter-proximal Nucleosomes

(2013) Boseon Byeon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Small Molecule Inhibitor of Polycomb Repressive Complex 1 Inhibits Ubiquitin Signaling at DNA Double-strand Breaks

(2013) Ismail Hassan Ismail et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

(2013) Cristina Escribano-Díaz et al.   MOLECULAR CELL

Double-strand break repair: 53BP1 comes into focus

(2013) Stephanie Panier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3

(2013) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection

(2013) Andreas Kakarougkas et al.   NUCLEIC ACIDS RESEARCH

A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining

(2013) Anastazja Grabarz et al.   Cell Reports

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

(2012) Katharina Schlacher et al.   CANCER CELL

A DNA-Damage Selective Role for BRCA1 E3 Ligase in Claspin Ubiquitylation, CHK1 Activation, and DNA Repair

(2012) Ko Sato et al.   CURRENT BIOLOGY

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions

(2012) Nozomi Tomimatsu et al.   DNA REPAIR

BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair

(2012) J. R. Chapman et al.   JOURNAL OF CELL SCIENCE

The Saccharomyces cerevisiae Chromatin Remodeler Fun30 Regulates DNA End Resection and Checkpoint Deactivation

(2012) V. V. Eapen et al.   MOLECULAR AND CELLULAR BIOLOGY

A Novel Function for BRCA1 In Crosslink Repair

(2012) David T. Long et al.   MOLECULAR CELL

The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection

(2012) Thomas Costelloe et al.   NATURE

The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends

(2012) Xuefeng Chen et al.   NATURE

BRCA1 RING Function Is Essential for Tumor Suppression but Dispensable for Therapy Resistance

(2011) Rinske Drost et al.   CANCER CELL

Solution Structure of RING Finger-like Domain of Retinoblastoma-binding Protein-6 (RBBP6) Suggests It Functions as a U-box

(2011) Mautin A. Kappo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Symmetry and Asymmetry of the RING–RING Dimer of Rad18

(2011) Anding Huang et al.   JOURNAL OF MOLECULAR BIOLOGY

Maintenance of Silent Chromatin through Replication Requires SWI/SNF-like Chromatin Remodeler SMARCAD1

(2011) Samuel P. Rowbotham et al.   MOLECULAR CELL

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing

(2011) Quan Zhu et al.   NATURE

Mechanism of ubiquitylation by dimeric RING ligase RNF4

(2011) Anna Plechanovová et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

The Snf2 Homolog Fun30 Acts as a Homodimeric ATP-dependent Chromatin-remodeling Enzyme

(2010) Salma Awad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of ATM and the Damage Response Mediator Proteins 53BP1 and MDC1 in the Maintenance of G2/M Checkpoint Arrest

(2010) A. Shibata et al.   MOLECULAR AND CELLULAR BIOLOGY

The SNF2-Family Member Fun30 Promotes Gene Silencing in Heterochromatic Loci

(2009) Ana Neves-Costa et al.   PLoS One

E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks

(2008) L. J. Reid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA