ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Mitochondrial membrane biogenesis: A new pathway for lipid transport mediated by PERK/E-Syt1 complex

(2023) Sébastien Leterme et al.   JOURNAL OF CELL BIOLOGY

PERK recruits E-Syt1 at ER–mitochondria contacts for mitochondrial lipid transport and respiration

(2023) Maria Livia Sassano et al.   JOURNAL OF CELL BIOLOGY

Phospholipid Membrane Transport and Associated Diseases

(2022) Raúl Ventura et al.   Biomedicines

ER-mitochondria contact sites; a multifaceted factory for Ca2+ signaling and lipid transport

(2022) Maria Livia Sassano et al.   Frontiers in Cell and Developmental Biology

SYNJ2BP Improves the Production of Lentiviral Envelope Protein by Facilitating the Formation of Mitochondrion-Associated Endoplasmic Reticulum Membrane

(2022) Yingyi Duan et al.   JOURNAL OF VIROLOGY

Altered SYNJ2BP-mediated mitochondrial-ER contacts in motor neuron disease

(2022) Naemeh Pourshafie et al.   NEUROBIOLOGY OF DISEASE

ORP5/8 and MIB/MICOS link ER-mitochondria and intra-mitochondrial contacts for non-vesicular transport of phosphatidylserine

(2022) Vera F. Monteiro-Cardoso et al.   Cell Reports

STIM Proteins and Regulation of SOCE in ER-PM Junctions

(2022) Moaz Ahmad et al.   Biomolecules

Expression of Synj2bp in mouse liver regulates the extent of wrappER-mitochondria contact to maintain hepatic lipid homeostasis

(2022) Nicolò Ilacqua et al.   Biology Direct

The Complex Dance of Organelles during Mitochondrial Division

(2021) Luis-Carlos Tábara et al.   TRENDS IN CELL BIOLOGY

PDZD8 mediated lipid transfer at ER-LE/lys contacts is required for LE/lys positioning and neurite outgrowth

(2021) Yuan Gao et al.   JOURNAL OF CELL SCIENCE

Phospholipid transfer function of PTPIP51 at mitochondria‐associated ER membranes

(2021) Hyun Ku Yeo et al.   EMBO REPORTS

VPS13D bridges the ER to mitochondria and peroxisomes via Miro

(2021) Andrés Guillén-Samander et al.   JOURNAL OF CELL BIOLOGY

A proximity-dependent biotinylation map of a human cell

(2021) Christopher D. Go et al.   NATURE

Structural basis of human PDZD8–Rab7 interaction for the ER-late endosome tethering

(2021) Haider Khan et al.   Scientific Reports

Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans

(2021) Lidan Zeng et al.   PLoS Genetics

Stepwise membrane binding of extended synaptotagmins revealed by optical tweezers

(2021) Jinghua Ge et al.   Nature Chemical Biology

Serine palmitoyltransferase assembles at ER–mitochondria contact sites

(2021) Mari J Aaltonen et al.   Life Science Alliance

The cell biology of mitochondrial membrane dynamics

(2020) Marta Giacomello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lipid homeostasis in mitochondria

(2020) Yasushi Tamura et al.   BIOLOGICAL CHEMISTRY

Reign in the membrane: How common lipids govern mitochondrial function

(2020) Katsuhiko Funai et al.   CURRENT OPINION IN CELL BIOLOGY

Phospholipid ebb and flow makes mitochondria go

(2020) Michelle Grace Acoba et al.   JOURNAL OF CELL BIOLOGY

PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria

(2020) Yael Elbaz-Alon et al.   Nature Communications

A High-Density Human Mitochondrial Proximity Interaction Network

(2020) Hana Antonicka et al.   Cell Metabolism

Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation

(2020) Michiko Shirane et al.   Nature Communications

The short isoform of extended synaptotagmin-2 controls Ca2+ dynamics in T cells via interaction with STIM1

(2020) Jin Seok Woo et al.   Scientific Reports

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

SMP domain proteins in membrane lipid dynamics

(2019) Darshini Jeyasimman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

(2019) María Isabel Hernández-Alvarez et al.   CELL

Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins

(2019) Jian Xiao et al.   Science China-Life Sciences

IP3 Receptor Plasticity Underlying Diverse Functions

(2019) Kozo Hamada et al.   Annual Review of Physiology

The role of the mitochondria and the endoplasmic reticulum contact sites in the development of the immune responses

(2018) Denis Martinvalet   Cell Death & Disease

Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics

(2018) Justyna Janikiewicz et al.   Cell Death & Disease

Mitochondria-associated membranes (MAMs) and inflammation

(2018) Sonia Missiroli et al.   Cell Death & Disease

Calcium, mitochondria and cell metabolism: A functional triangle in bioenergetics

(2018) Alice Rossi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ProHits-viz: a suite of web tools for visualizing interaction proteomics data

(2017) James D R Knight et al.   NATURE METHODS

ER-mitochondria tethering by PDZD8 regulates Ca2+dynamics in mammalian neurons

(2017) Yusuke Hirabayashi et al.   SCIENCE

Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation

(2017) Victoria Hung et al.   eLife

SMP-domain proteins at membrane contact sites: Structure and function

(2016) Karin M. Reinisch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility

(2016) Michel G. Tremblay et al.   CELL CYCLE

The coming of age of the mitochondria–ER contact: a matter of thickness

(2016) M Giacomello et al.   CELL DEATH AND DIFFERENTIATION

A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites

(2016) Michal Eisenberg-Bord et al.   DEVELOPMENTAL CELL

ORP5/ORP8 localize to endoplasmic reticulum–mitochondria contacts and are involved in mitochondrial function

(2016) Romain Galmes et al.   EMBO REPORTS

An inducible ER–Golgi tether facilitates ceramide transport to alleviate lipotoxicity

(2016) Li-Ka Liu et al.   JOURNAL OF CELL BIOLOGY

Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction

(2016) Alessandra Sclip et al.   PLoS One

Study of Endoplasmic Reticulum and Mitochondria Interactions by In Situ Proximity Ligation Assay in Fixed Cells

(2016) Emily Tubbs et al.   Jove-Journal of Visualized Experiments

A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro

(2016) Rieko Kojima et al.   Scientific Reports

Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy

(2015) Paul Hsu et al.   Autophagy

The endoplasmic reticulum: structure, function and response to cellular signaling

(2015) Dianne S. Schwarz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering

(2015) O. Idevall-Hagren et al.   EMBO JOURNAL

An automated shotgun lipidomics platform for high throughput, comprehensive, and quantitative analysis of blood plasma intact lipids

(2015) Michal A. Surma et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death

(2015) Julien Prudent et al.   MOLECULAR CELL

Three-dimensional architecture of extended synaptotagmin-mediated endoplasmic reticulum–plasma membrane contact sites

(2015) Rubén Fernández-Busnadiego et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved SMP domains of the ERMES complex bind phospholipids and mediate tether assembly

(2015) Andrew P. AhYoung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling through C2 domains: More than one lipid target

(2014) Senena Corbalan-Garcia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA

(2014) Junji Suzuki et al.   Nature Communications

Translocation between PI(4,5)P2-poor and PI(4,5)P2-rich microdomains during store depletion determines STIM1 conformation and Orai1 gating

(2014) Jozsef Maléth et al.   Nature Communications

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

(2014) Radu Stoica et al.   Nature Communications

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

Involvement of cardiolipin in tBID-induced activation of BAX during apoptosis

(2013) Etienne Raemy et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes

(2013) Massimo Bonora et al.   Nature Protocols

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Feedback Regulation of Receptor-Induced Ca2+ Signaling Mediated by E-Syt1 and Nir2 at Endoplasmic Reticulum-Plasma Membrane Junctions

(2013) Chi-Lun Chang et al.   Cell Reports

Phosphatidylethanolamine and Cardiolipin Differentially Affect the Stability of Mitochondrial Respiratory Chain Supercomplexes

(2012) Lena Böttinger et al.   JOURNAL OF MOLECULAR BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

LipidXplorer: A Software for Consensual Cross-Platform Lipidomics

(2012) Ronny Herzog et al.   PLoS One

Evolutionary Diversity of the Mitochondrial Calcium Uniporter

(2012) A. G. Bick et al.   SCIENCE

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

(2011) Kurt J. De Vos et al.   HUMAN MOLECULAR GENETICS

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Defining human ERAD networks through an integrative mapping strategy

(2011) John C. Christianson et al.   NATURE CELL BIOLOGY

Membrane lipidome of an epithelial cell line

(2011) Julio L. Sampaio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language

(2011) Ronny Herzog et al.   GENOME BIOLOGY

Homology of SMP domains to the TULIP superfamily of lipid-binding proteins provides a structural basis for lipid exchange between ER and mitochondria

(2010) Klaus O. Kopec et al.   BIOINFORMATICS

Mutation in TACO1, encoding a translational activator of COX I, results in cytochrome c oxidase deficiency and late-onset Leigh syndrome

(2009) Woranontee Weraarpachai et al.   NATURE GENETICS

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

(2009) C. S. Ejsing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

Respiratory Active Mitochondrial Supercomplexes

(2008) Rebeca Acín-Pérez et al.   MOLECULAR CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE