Phospholipid ebb and flow makes mitochondria go

Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1

(2020) Liming Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane

(2020) Yifan Ge et al.   eLife

Cryo-EM reconstruction of a VPS13 fragment reveals a long groove to channel lipids between membranes

(2020) PeiQi Li et al.   JOURNAL OF CELL BIOLOGY

Phospholipid Acyl Chain Diversity Controls the Tissue-Specific Assembly of Mitochondrial Cardiolipins

(2020) Gregor Oemer et al.   Cell Reports

Vps39 is required for ethanolamine-stimulated elevation in mitochondrial phosphatidylethanolamine

(2020) Donna M. Iadarola et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Maintenance of Cardiolipin and Crista Structure Requires Cooperative Functions of Mitochondrial Dynamics and Phospholipid Transport

(2019) Rieko Kojima et al.   Cell Reports

Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc1 complex function

(2019) Elizabeth Calzada et al.   Nature Communications

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins

(2019) Xeni Miliara et al.   Nature Communications

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

(2019) María Isabel Hernández-Alvarez et al.   CELL

Assembly of the complexes of oxidative phosphorylation triggers the remodeling of cardiolipin

(2019) Yang Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1

(2019) Katja Faelber et al.   NATURE

H+ transport is an integral function of the mitochondrial ADP/ATP carrier

(2019) Ambre M. Bertholet et al.   NATURE

Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent

(2019) Dane M Wolf et al.   EMBO JOURNAL

Lipid signalling drives proteolytic rewiring of mitochondria by YME1L

(2019) Thomas MacVicar et al.   NATURE

Structure of a mitochondrial ATP synthase with bound native cardiolipin

(2019) Alexander Mühleip et al.   eLife

The lysophosphatidic acid acyltransferases (acylglycerophosphate acyltransferases) family

(2018) Ryan M. Bradley et al.   CURRENT OPINION IN LIPIDOLOGY

Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER

(2018) Jonathan R. Friedman et al.   DEVELOPMENTAL CELL

Vps39 Interacts with Tom40 to Establish One of Two Functionally Distinct Vacuole-Mitochondria Contact Sites

(2018) Ayelén González Montoro et al.   DEVELOPMENTAL CELL

PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria

(2018) Shotaro Saita et al.   EMBO JOURNAL

Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites

(2018) Björn D.M. Bean et al.   JOURNAL OF CELL BIOLOGY

Assembly of the Mitochondrial Cristae Organizer Mic10 Is Regulated by Mic26–Mic27 Antagonism and Cardiolipin

(2018) Heike Rampelt et al.   JOURNAL OF MOLECULAR BIOLOGY

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

(2018) Yvette C. Wong et al.   NATURE

Understanding the diversity of membrane lipid composition

(2018) Takeshi Harayama et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

(2018) Nikit Kumar et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial Complex I Activity Is Required for Maximal Autophagy

(2018) Hala Elnakat Thomas et al.   Cell Reports

FAM92A1 is a BAR domain protein required for mitochondrial ultrastructure and function

(2018) Liang Wang et al.   JOURNAL OF CELL BIOLOGY

Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes

(2018) Louise H. Wong et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The MICOS component Mic60 displays a conserved membrane-bending activity that is necessary for normal cristae morphology

(2017) Daryna Tarasenko et al.   JOURNAL OF CELL BIOLOGY

Vps13-Mcp1 interact at vacuole–mitochondria interfaces and bypass ER–mitochondria contact sites

(2017) Arun T. John Peter et al.   JOURNAL OF CELL BIOLOGY

Structure–function insights into direct lipid transfer between membranes by Mmm1–Mdm12 of ERMES

(2017) Shin Kawano et al.   JOURNAL OF CELL BIOLOGY

Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex

(2017) Yilin Kang et al.   MOLECULAR CELL

Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria

(2017) Milena Vukotic et al.   MOLECULAR CELL

Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin

(2017) Tadato Ban et al.   NATURE CELL BIOLOGY

Crystal structures of Mmm1 and Mdm12–Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites

(2017) Hanbin Jeong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ER membrane protein complex is a transmembrane domain insertase

(2017) Alina Guna et al.   SCIENCE

ER-mitochondria tethering by PDZD8 regulates Ca2+dynamics in mammalian neurons

(2017) Yusuke Hirabayashi et al.   SCIENCE

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions

(2017) Manuel Hessenberger et al.   Nature Communications

Identification of the N-terminal transmembrane domain of StarD7 and its importance for mitochondrial outer membrane localization and phosphatidylcholine transfer

(2017) Yasuhiro Horibata et al.   Scientific Reports

Cooperative function of Fmp30, Mdm31, and Mdm32 in Ups1-independent cardiolipin accumulation in the yeast Saccharomyces cerevisiae

(2017) Non Miyata et al.   Scientific Reports

Cardiolipin mediates membrane and channel interactions of the mitochondrial TIM23 protein import complex receptor Tim50

(2017) Ketan Malhotra et al.   Science Advances

Cryo-EM Studies of Drp1 Reveal Cardiolipin Interactions that Activate the Helical Oligomer

(2017) Christopher A. Francy et al.   Scientific Reports

NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy

(2016) V E Kagan et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial contact site and cristae organizing system

(2016) Martin van der Laan et al.   CURRENT OPINION IN CELL BIOLOGY

SLC25A46is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome

(2016) Alexandre Janer et al.   EMBO Molecular Medicine

Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex

(2016) Hanbin Jeong et al.   EMBO REPORTS

ORP5/ORP8 localize to endoplasmic reticulum–mitochondria contacts and are involved in mitochondrial function

(2016) Romain Galmes et al.   EMBO REPORTS

Defining functional classes of Barth syndrome mutation in humans

(2016) Ya-Wen Lu et al.   HUMAN MOLECULAR GENETICS

StarD7 Protein Deficiency Adversely Affects the Phosphatidylcholine Composition, Respiratory Activity, and Cristae Structure of Mitochondria

(2016) Yasuhiro Horibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylcholine Affects Inner Membrane Protein Translocases of Mitochondria

(2016) Max-Hinderk Schuler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylserine transport by Ups2–Mdm35 in respiration-active mitochondria

(2016) Non Miyata et al.   JOURNAL OF CELL BIOLOGY

MICOS and phospholipid transfer by Ups2–Mdm35 organize membrane lipid synthesis in mitochondria

(2016) Mari J. Aaltonen et al.   JOURNAL OF CELL BIOLOGY

Endosome–mitochondria interactions are modulated by iron release from transferrin

(2016) Anupam Das et al.   JOURNAL OF CELL BIOLOGY

OPA1 processing in cell death and disease – the long and short of it

(2016) Thomas MacVicar et al.   JOURNAL OF CELL SCIENCE

Specific requirements of nonbilayer phospholipids in mitochondrial respiratory chain function and formation

(2016) Charli D. Baker et al.   MOLECULAR BIOLOGY OF THE CELL

Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites

(2016) Jae-Sook Park et al.   MOLECULAR BIOLOGY OF THE CELL

Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis

(2016) Yongping Zhang et al.   MOLECULAR CELL

Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology

(2016) Alexander Hahn et al.   MOLECULAR CELL

Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division

(2016) Yoshihiro Adachi et al.   MOLECULAR CELL

Loss of protein association causes cardiolipin degradation in Barth syndrome

(2016) Yang Xu et al.   Nature Chemical Biology

Cardiolipin puts the seal on ATP synthase

(2016) Ahmad Reza Mehdipour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid somersaults: Uncovering the mechanisms of protein-mediated lipid flipping

(2016) Thomas Günther Pomorski et al.   PROGRESS IN LIPID RESEARCH

An evidence based hypothesis on the existence of two pathways of mitochondrial crista formation

(2016) Max E Harner et al.   eLife

A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro

(2016) Rieko Kojima et al.   Scientific Reports

Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy

(2015) Paul Hsu et al.   Autophagy

Acylglycerophosphate acyltransferase 4 (AGPAT4) is a mitochondrial lysophosphatidic acid acyltransferase that regulates brain phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol levels

(2015) Ryan M. Bradley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses

(2015) Marielle S. Köberlin et al.   CELL

Phosphatidylethanolamine positively regulates autophagy and longevity

(2015) P Rockenfeller et al.   CELL DEATH AND DIFFERENTIATION

Mic10 Oligomerizes to Bend Mitochondrial Inner Membranes at Cristae Junctions

(2015) Mariam Barbot et al.   Cell Metabolism

Central Role of Mic10 in the Mitochondrial Contact Site and Cristae Organizing System

(2015) Maria Bohnert et al.   Cell Metabolism

Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex

(2015) F. Yu et al.   EMBO REPORTS

Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes

(2015) X. Miliara et al.   EMBO REPORTS

Phosphatidylcholine Affects the Role of the Sorting and Assembly Machinery in the Biogenesis of Mitochondrial β-Barrel Proteins

(2015) Max-Hinderk Schuler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanoenzymatic Core of Dynamin-related Protein 1 Comprises the Minimal Machinery Required for Membrane Constriction

(2015) Christopher A. Francy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ltc1 is an ER-localized sterol transporter and a component of ER–mitochondria and ER–vacuole contacts

(2015) Andrew Murley et al.   JOURNAL OF CELL BIOLOGY

ER–mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13

(2015) Alexander B. Lang et al.   JOURNAL OF CELL BIOLOGY

Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission

(2015) Natalia Stepanyants et al.   MOLECULAR BIOLOGY OF THE CELL

Uncoupling protein 1 binds one nucleotide per monomer and is stabilized by tightly bound cardiolipin

(2015) Yang Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved SMP domains of the ERMES complex bind phospholipids and mediate tether assembly

(2015) Andrew P. AhYoung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of membrane contact sites in protein import into mitochondria

(2015) Susanne E. Horvath et al.   PROTEIN SCIENCE

Structural and mechanistic insights into phospholipid transfer by Ups1–Mdm35 in mitochondria

(2015) Yasunori Watanabe et al.   Nature Communications

Interaction of MDM33 with mitochondrial inner membrane homeostasis pathways in yeast

(2015) Till Klecker et al.   Scientific Reports

Lam6 Regulates the Extent of Contacts between Organelles

(2015) Yael Elbaz-Alon et al.   Cell Reports

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

(2015) Jonathan R Friedman et al.   eLife

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

(2015) Alberto T Gatta et al.   eLife

Dividing Cells Regulate Their Lipid Composition and Localization

(2014) G. Ekin Atilla-Gokcumen et al.   CELL

DNAJC19, a Mitochondrial Cochaperone Associated with Cardiomyopathy, Forms a Complex with Prohibitins to Regulate Cardiolipin Remodeling

(2014) Ricarda Richter-Dennerlein et al.   Cell Metabolism

Proteolytic Cleavage of Opa1 Stimulates Mitochondrial Inner Membrane Fusion and Couples Fusion to Oxidative Phosphorylation

(2014) Prashant Mishra et al.   Cell Metabolism

Mitochondria and Melanosomes Establish Physical Contacts Modulated by Mfn2 and Involved in Organelle Biogenesis

(2014) Tiziana Daniele et al.   CURRENT BIOLOGY

A Dynamic Interface between Vacuoles and Mitochondria in Yeast

(2014) Yael Elbaz-Alon et al.   DEVELOPMENTAL CELL

Cellular Metabolism Regulates Contact Sites between Vacuoles and Mitochondria

(2014) Carina Hönscher et al.   DEVELOPMENTAL CELL

OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand

(2014) D. A. Patten et al.   EMBO JOURNAL

Roles and regulation of phospholipid scramblases

(2014) Karthik M. Kodigepalli et al.   FEBS LETTERS

Phosphatidic Acid (PA)-preferring Phospholipase A1Regulates Mitochondrial Dynamics

(2014) Takashi Baba et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission

(2014) Patrick J. Macdonald et al.   MOLECULAR BIOLOGY OF THE CELL

A mitochondrial pathway for biosynthesis of lipid mediators

(2014) Yulia Y. Tyurina et al.   Nature Chemistry

Specific Interaction with Cardiolipin Triggers Functional Activation of Dynamin-Related Protein 1

(2014) Itsasne Bustillo-Zabalbeitia et al.   PLoS One

Phospholipid Synthesis and Transport in Mammalian Cells

(2014) Jean E. Vance   TRAFFIC

A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria

(2014) Sujoy Lahiri et al.   PLOS BIOLOGY

Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture

(2014) Max Emanuel Harner et al.   eLife

Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux

(2013) Hiroshi Matsuzaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRIAP1/PRELI Complexes Prevent Apoptosis by Mediating Intramitochondrial Transport of Phosphatidic Acid

(2013) Christoph Potting et al.   Cell Metabolism

Tam41 Is a CDP-Diacylglycerol Synthase Required for Cardiolipin Biosynthesis in Mitochondria

(2013) Yasushi Tamura et al.   Cell Metabolism

The topology and regulation of cardiolipin biosynthesis and remodeling in yeast

(2013) Matthew G. Baile et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Mitochondria-type GPAT is required for mitochondrial fusion

(2013) Yohsuke Ohba et al.   EMBO JOURNAL

Tyrosine Sulfation of Chemokine Receptor CCR2 Enhances Interactions with Both Monomeric and Dimeric Forms of the Chemokine Monocyte Chemoattractant Protein-1 (MCP-1)

(2013) Joshua H. Y. Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unremodeled and Remodeled Cardiolipin Are Functionally Indistinguishable in Yeast

(2013) Matthew G. Baile et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of the Cardiolipin-specific Phospholipase Cld1 Rescues Growth and Life Span Defects in the Tafazzin Mutant

(2013) Cunqi Ye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Phosphatidylethanolamine in the Biogenesis of Mitochondrial Outer Membrane Proteins

(2013) Thomas Becker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deacylation on the matrix side of the mitochondrial inner membrane regulates cardiolipin remodeling

(2013) Matthew G. Baile et al.   MOLECULAR BIOLOGY OF THE CELL

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

(2013) Charleen T. Chu et al.   NATURE CELL BIOLOGY

Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

(2013) Stephen L. Archer   NEW ENGLAND JOURNAL OF MEDICINE

Assessing Phospholipase A2 Activity toward Cardiolipin by Mass Spectrometry

(2013) Yuan-Hao Hsu et al.   PLoS One

APOOL Is a Cardiolipin-Binding Constituent of the Mitofilin/MINOS Protein Complex Determining Cristae Morphology in Mammalian Mitochondria

(2013) Tobias A. Weber et al.   PLoS One

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

(2013) E. Lapuente-Brun et al.   SCIENCE

The stability and activity of respiratory Complex II is cardiolipin-dependent

(2012) Christine T. Schwall et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Phosphatidylethanolamine Biosynthesis in Mitochondria

(2012) Yasushi Tamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiolipin and Mitochondrial Phosphatidylethanolamine Have Overlapping Functions in Mitochondrial Fusion inSaccharomyces cerevisiae

(2012) Amit S. Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylethanolamine Deficiency in Mammalian Mitochondria Impairs Oxidative Phosphorylation and Alters Mitochondrial Morphology

(2012) Guergana Tasseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual Function of Mitochondrial Nm23-H4 Protein in Phosphotransfer and Intermembrane Lipid Transfer

(2012) Uwe Schlattner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylserine Decarboxylase 1 (Psd1) Promotes Mitochondrial Fusion by Regulating the Biophysical Properties of the Mitochondrial Membrane and Alternative Topogenesis of Mitochondrial Genome Maintenance Protein 1 (Mgm1)

(2012) Eliana Y. L. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Processing and Topology of the Yeast Mitochondrial Phosphatidylserine Decarboxylase 1

(2012) Susanne E. Horvath et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role for Two Conserved Intermembrane Space Proteins, Ups1p and Up2p, in Intra-mitochondrial Phospholipid Trafficking

(2012) Yasushi Tamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ER-shaping proteins facilitate lipid exchange between the ER and mitochondria in S. cerevisiae

(2012) C. Voss et al.   JOURNAL OF CELL SCIENCE

Role of MINOS in Mitochondrial Membrane Architecture: Cristae Morphology and Outer Membrane Interactions Differentially Depend on Mitofilin Domains

(2012) Ralf M. Zerbes et al.   JOURNAL OF MOLECULAR BIOLOGY

Phosphatidylethanolamine and Cardiolipin Differentially Affect the Stability of Mitochondrial Respiratory Chain Supercomplexes

(2012) Lena Böttinger et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae

(2012) K. M. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex

(2012) C. Brocker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intramitochondrial Transport of Phosphatidic Acid in Yeast by a Lipid Transfer Protein

(2012) M. Connerth et al.   SCIENCE

Gem1 and ERMES Do Not Directly Affect Phosphatidylserine Transport from ER to Mitochondria or Mitochondrial Inheritance

(2012) Tammy T. Nguyen et al.   TRAFFIC

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

Mitochondrial Phosphatase PTPMT1 Is Essential for Cardiolipin Biosynthesis

(2011) Ji Zhang et al.   Cell Metabolism

piRNA-Associated Germline Nuage Formation and Spermatogenesis Require MitoPLD Profusogenic Mitochondrial-Surface Lipid Signaling

(2011) Huiyan Huang et al.   DEVELOPMENTAL CELL

The mitochondrial contact site complex, a determinant of mitochondrial architecture

(2011) Max Harner et al.   EMBO JOURNAL

Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1

(2011) Thorsten Althoff et al.   EMBO JOURNAL

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

(2011) Kurt J. De Vos et al.   HUMAN MOLECULAR GENETICS

Deficiency of Cardiolipin Synthase Causes Abnormal Mitochondrial Function and Morphology in Germ Cells ofCaenorhabditis elegans

(2011) Taro Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

(2011) Suzanne Hoppins et al.   JOURNAL OF CELL BIOLOGY

Barth syndrome mutations that cause tafazzin complex lability

(2011) Steven M. Claypool et al.   JOURNAL OF CELL BIOLOGY

Defining human ERAD networks through an integrative mapping strategy

(2011) John C. Christianson et al.   NATURE CELL BIOLOGY

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

The complexity of cardiolipin in health and disease

(2011) Steven M. Claypool et al.   TRENDS IN BIOCHEMICAL SCIENCES

Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization

(2010) Sylvie Montessuit et al.   CELL

Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity

(2010) Jia Li et al.   Cell Metabolism

Mdm35p imports Ups proteins into the mitochondrial intermembrane space by functional complex formation

(2010) Yasushi Tamura et al.   EMBO JOURNAL

A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4

(2010) Christof Osman et al.   EMBO JOURNAL

Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction

(2010) Ryota Iwasawa et al.   EMBO JOURNAL

Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35

(2010) Christoph Potting et al.   EMBO JOURNAL

Characterization of a Transgenic Short Hairpin RNA-Induced Murine Model of Tafazzin Deficiency

(2010) Meghan S. Soustek et al.   HUMAN GENE THERAPY

OPA1 disease alleles causing dominant optic atrophy have defects in cardiolipin-stimulated GTP hydrolysis and membrane tubulation

(2010) Tadato Ban et al.   HUMAN MOLECULAR GENETICS

Cardiac and Skeletal Muscle Defects in a Mouse Model of Human Barth Syndrome

(2010) Devrim Acehan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria

(2010) Sneha S. Prasad et al.   JOURNAL OF LIPID RESEARCH

Cardiolipin and monolysocardiolipin analysis in fibroblasts, lymphocytes, and tissues using high-performance liquid chromatography–mass spectrometry as a diagnostic test for Barth syndrome

(2009) Riekelt H. Houtkooper et al.   ANALYTICAL BIOCHEMISTRY

The Dynamin-Related Protein Mgm1p Assembles into Oligomers and Hydrolyzes GTP To Function in Mitochondrial Membrane Fusion†

(2009) Gabriela Meglei et al.   BIOCHEMISTRY

Mitochondrial Cardiolipin Involved in Outer-Membrane Protein Biogenesis: Implications for Barth Syndrome

(2009) Natalia Gebert et al.   CURRENT BIOLOGY

Phospholipid Association Is Essential for Dynamin-related Protein Mgm1 to Function in Mitochondrial Membrane Fusion

(2009) Jarungjit Rujiviphat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of the Human Mitochondrial Linoleoyl-coenzyme A Monolysocardiolipin Acyltransferase (MLCL AT-1)

(2009) William A. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Cardiolipin-specific Phospholipase Encoded by the GeneCLD1(YGR110W) in Yeast

(2009) Andreas Beranek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Development of a Metabolic Disease Phenotype in CTP:Phosphoethanolamine Cytidylyltransferase-deficient Mice

(2009) Morgan D. Fullerton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

StarD7 Mediates the Intracellular Trafficking of Phosphatidylcholine to Mitochondria

(2009) Yasuhiro Horibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

(2009) Rachel M. DeVay et al.   JOURNAL OF CELL BIOLOGY

Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria

(2009) Yasushi Tamura et al.   JOURNAL OF CELL BIOLOGY

The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria

(2009) Christof Osman et al.   JOURNAL OF CELL BIOLOGY

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Sue/g

(2009) Regina Rabl et al.   JOURNAL OF CELL BIOLOGY

Compartment-specific Synthesis of Phosphatidylethanolamine Is Required for Normal Heavy Metal Resistance

(2009) Kailash Gulshan et al.   MOLECULAR BIOLOGY OF THE CELL

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

(2008) Mike Strauss et al.   EMBO JOURNAL

AGPAT6 Is a Novel Microsomal Glycerol-3-phosphate Acyltransferase

(2008) Yan Qun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nucleoside Diphosphate Kinase D (NM23-H4) Binds the Inner Mitochondrial Membrane with High Affinity to Cardiolipin and Couples Nucleotide Transfer with Respiration

(2008) Malgorzata Tokarska-Schlattner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

(2008) Francois Gonzalvez et al.   JOURNAL OF CELL BIOLOGY

Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane

(2008) Steven M. Claypool et al.   JOURNAL OF CELL BIOLOGY

The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids

(2008) Yang Zhao et al.   JOURNAL OF LIPID RESEARCH

Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer

(2008) Michael A. Kiebish et al.   JOURNAL OF LIPID RESEARCH

Identification of a novelsn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient inAgpat6−/−mice

(2008) Cynthia A. Nagle et al.   JOURNAL OF LIPID RESEARCH

The Cardiolipin Transacylase, Tafazzin, Associates with Two Distinct Respiratory Components Providing Insight into Barth Syndrome

(2008) Steven M. Claypool et al.   MOLECULAR BIOLOGY OF THE CELL

Respiratory Active Mitochondrial Supercomplexes

(2008) Rebeca Acín-Pérez et al.   MOLECULAR CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE