The pyruvate dehydrogenase complex regulates mitophagic trafficking and protein phosphorylation

Regulation and metabolic functions of mTORC1 and mTORC2

(2021) Angelia Szwed et al.   PHYSIOLOGICAL REVIEWS

Monitoring checkpoints of metabolism and protein biogenesis in mitochondria by Phos-tag technology

(2021) Corvin Walter et al.   Journal of Proteomics

Autophagy accounts for approximately one-third of mitochondrial protein turnover and is protein selective

(2019) Evelyn S. Vincow et al.   Autophagy

Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

(2019) Panagiota Kolitsida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folding and assembly defects of pyruvate dehydrogenase deficiency-related variants in the E1α subunit of the pyruvate dehydrogenase complex

(2018) Srdja Drakulic et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy in Age-Associated Neurodegeneration

(2018) Athanasios Metaxakis et al.   Cells

Integrative proteomics and biochemical analyses define Ptc6p as theSaccharomyces cerevisiaepyruvate dehydrogenase phosphatase

(2017) Xiao Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial phosphoproteomics of mammalian tissues

(2017) Rikke Kruse et al.   MITOCHONDRION

Ptc7p Dephosphorylates Select Mitochondrial Proteins to Enhance Metabolic Function

(2017) Xiao Guo et al.   Cell Reports

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Mitophagy as a stress response in mammalian cells and in respiring S. cerevisiae

(2016) Hagai Abeliovich et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mitochondrial biogenesis and clearance: a balancing act

(2016) Christina Ploumi et al.   FEBS Journal

Robust, Sensitive, and Automated Phosphopeptide Enrichment Optimized for Low Sample Amounts Applied to Primary Hippocampal Neurons

(2016) Harm Post et al.   JOURNAL OF PROTEOME RESEARCH

TOR Complexes and the Maintenance of Cellular Homeostasis

(2016) Sandra Eltschinger et al.   TRENDS IN CELL BIOLOGY

Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts

(2015) Jon Sin et al.   Autophagy

Pyruvate stimulates mitophagy via PINK1 stabilization

(2015) Sungwoo Park et al.   CELLULAR SIGNALLING

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

(2015) Tomokazu Murakawa et al.   Nature Communications

Proteomic Analysis Reveals a Novel Function of the Kinase Sat4p in Saccharomyces cerevisiae Mitochondria

(2014) Uta Gey et al.   PLoS One

Ptc6 Is Required for Proper Rapamycin-Induced Down-Regulation of the Genes Coding for Ribosomal and rRNA Processing Proteins in S. cerevisiae

(2013) Asier González et al.   PLoS One

Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model

(2013) R. H. Hamalainen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo

(2013) E. S. Vincow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy

(2013) Hagai Abeliovich et al.   Nature Communications

Mitochondrial disorders as windows into an ancient organelle

(2012) Scott B. Vafai et al.   NATURE

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

Identification and Functional Expression of the Mitochondrial Pyruvate Carrier

(2012) S. Herzig et al.   SCIENCE

Atomic structures of the eukaryotic ribosome

(2012) Sebastian Klinge et al.   TRENDS IN BIOCHEMICAL SCIENCES

Phosphorylation of Serine 114 on Atg32 mediates mitophagy

(2011) Yoshimasa Aoki et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative Phosphoproteomics Identifies Substrates and Functional Modules of Aurora and Polo-Like Kinase Activities in Mitotic Cells

(2011) A. N. Kettenbach et al.   Science Signaling

A Global Protein Kinase and Phosphatase Interaction Network in Yeast

(2010) A. Breitkreutz et al.   SCIENCE

Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy

(2009) Tomotake Kanki et al.   DEVELOPMENTAL CELL

Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy

(2009) Koji Okamoto et al.   DEVELOPMENTAL CELL

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Aup1-mediated Regulation of Rtg3 during Mitophagy

(2009) Dikla Journo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Yeast Pyruvate Dehydrogenase Complex Is Regulated by a Concerted Activity of Two Kinases and Two Phosphatases

(2008) Uta Gey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY