NTRK1 knockdown induces mouse cognitive impairment and hippocampal neuronal damage through mitophagy suppression via inactivating the AMPK/ULK1/FUNDC1 pathway

Qiangjing tablets ameliorate asthenozoospermia via mitochondrial ubiquitination and mitophagy mediated by LKB1/AMPK/ULK1 signaling

(2023) Guangsen Li et al.   PHARMACEUTICAL BIOLOGY

The Role of PGC-1α-Mediated Mitochondrial Biogenesis in Neurons

(2023) Mengjie Chen et al.   NEUROCHEMICAL RESEARCH

Effects of all-trans and 9-cis retinoic acid on differentiating human neural stem cells in vitro

(2023) Barbara Kubickova et al.   TOXICOLOGY

Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons

(2022) Juliet Goldsmith et al.   NEURON

Isoquercetin alleviates sleep deprivation dependent hippocampal neurons damage by suppressing NLRP3-induced pyroptosis

(2022) Hairui Zhou et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Biochanin A alleviates cognitive impairment and hippocampal mitochondrial damage in ovariectomized APP/PS1 mice

(2022) Yue Hou et al.   PHYTOMEDICINE

Mitochondria-lysosome contact site dynamics and misregulation in neurodegenerative diseases

(2022) Jasmine Cisneros et al.   TRENDS IN NEUROSCIENCES

Mitochondrial autophagy: molecular mechanisms and implications for cardiovascular disease

(2022) Anqi Li et al.   Cell Death & Disease

Olfactory placode generates a diverse population of neurons expressing GnRH, somatostatin mRNA, neuropeptide Y, or calbindin in the chick forebrain

(2022) Shizuko Murakami et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Astragaloside IV Protects Detrusor from Partial Bladder Outlet Obstruction-Induced Oxidative Stress by Activating Mitophagy through AMPK-ULK1 Pathway

(2022) Xiaoyu Zhu et al.   Oxidative Medicine and Cellular Longevity

Treadmill exercise training alleviates diabetes-induced depressive-like behavior and cognitive impairment by improving hippocampal CA1 neurons injury in db/db mice

(2022) Zhongyuan Zhou et al.   BRAIN RESEARCH BULLETIN

FUNDC1 Mediated Mitophagy in Epileptic Hippocampal Neuronal Injury Induced by Magnesium-Free Fluid

(2022) Yinna Zhang et al.   NEUROCHEMICAL RESEARCH

Acute Hippocampal Damage as a Prognostic Biomarker for Cognitive Decline but Not for Epileptogenesis after Experimental Traumatic Brain Injury

(2022) Eppu Manninen et al.   Biomedicines

Electroacupuncture improves cognitive impairment in diabetic cognitive dysfunction rats by regulating the mitochondrial autophagy pathway

(2022) Xia Ge et al.   Journal of Physiological Sciences

Anti-apoptosis effect of recombinant human interleukin-11 in neonatal hypoxic-ischemic rats through activating the IL-11Rα/STAT3 signaling pathway

(2022) Ding Zuo et al.   Journal of Stroke & Cerebrovascular Diseases

Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling

(2022) Bin Chen et al.   NEUROCHEMICAL RESEARCH

Guanosine Prevents Spatial Memory Impairment and Hippocampal Damage Following Amyloid-β1–42 Administration in Mice

(2022) Victor Coelho et al.   Metabolites

Immunostaining for NeuN Does Not Show all Mature and Healthy Neurons in the Human and Pig Brain

(2021) Lauren Luijerink et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

NLRP3 Deficiency Protects Against Intermittent Hypoxia-Induced Neuroinflammation and Mitochondrial ROS by Promoting the PINK1-Parkin Pathway of Mitophagy in a Murine Model of Sleep Apnea

(2021) Xu Wu et al.   Frontiers in Immunology

LncRNA MEG3 Alleviates Diabetic Cognitive Impairments by Reducing Mitochondrial-Derived Apoptosis through Promotion of FUNDC1-Related Mitophagy via Rac1-ROS Axis

(2021) Zhihua Wang et al.   ACS Chemical Neuroscience

Mitochondrial Dysfunction as a Driver of Cognitive Impairment in Alzheimer’s Disease

(2021) Chanchal Sharma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adiponectin Mediates the Protection of H2S Against Chronic Restraint Stress-Induced Cognitive Impairment via Attenuating Hippocampal Damage

(2021) Qiong-Yan Tang et al.   Frontiers in Behavioral Neuroscience

Gene expression with corresponding pathways analysis in Gaucher disease

(2021) Łukasz Pawliński et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Combined exposure of alumina nanoparticles and chronic stress exacerbates hippocampal neuronal ferroptosis via activating IFN-γ/ASK1/JNK signaling pathway in rats

(2021) Haiyang Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway

(2021) Yao Zhao et al.   Journal of Neuroinflammation

Neuronal autophagy and mitophagy in Parkinson's disease

(2021) Britney N. Lizama et al.   MOLECULAR ASPECTS OF MEDICINE

Jianpi Qushi Heluo Formula alleviates renal damages in Passive Hemann nephritis in rats by upregulating Parkin-mediated mitochondrial autophagy

(2021) Xin-hui Wang et al.   Scientific Reports

Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis

(2021) Yuting Yan et al.   Cell Death & Disease

Investigation of a Novel NTRK1 Variation Causing Congenital Insensitivity to Pain With Anhidrosis

(2021) Kai Yang et al.   Frontiers in Genetics

Identification of novel variations in the NTRK1 gene causing congenital insensitivity to pain with anhidrosis

(2021) Shang Li et al.   Molecular Genetics & Genomic Medicine

FUNDC1: A Promising Mitophagy Regulator at the Mitochondria-Associated Membrane for Cardiovascular Diseases

(2021) Guoyong Li et al.   Frontiers in Cell and Developmental Biology

Glial Fibrillary Acidic Protein (GFAP): Neuroinflammation Biomarker in Acute Ischemic Stroke

(2021) Lisda Amalia   Journal of Inflammation Research

Resveratrol prevents benzo(a)pyrene-induced disruption of mitochondrial homeostasis via the AMPK signaling pathway in primary cultured neurons

(2020) Run-Run Kang et al.   ENVIRONMENTAL POLLUTION

Mechanical force modulates periodontal ligament stem cell characteristics during bone remodelling via TRPV4

(2020) Shan‐Shan Jin et al.   CELL PROLIFERATION

Ntrk1 mutation co-segregating with bipolar disorder and inherited kidney disease in a multiplex family causes defects in neuronal growth and depression-like behavior in mice

(2020) Kazuo Nakajima et al.   Translational Psychiatry

FUNDC1-dependent mitophagy induced by tPA protects neurons against cerebral ischemia-reperfusion injury

(2020) Ying Cai et al.   Redox Biology

Mitophagy and Neuroprotection

(2019) Guofeng Lou et al.   TRENDS IN MOLECULAR MEDICINE

Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission

(2019) Jin Wang et al.   Redox Biology

Ulk1/FUNDC1 Prevents Nerve Cells from Hypoxia-Induced Apoptosis by Promoting Cell Autophagy

(2018) Li Wang et al.   NEUROCHEMICAL RESEARCH

EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications

(2018) Zhenghao Li et al.   ONCOGENE

Supplementation of lycopene attenuates oxidative stress induced neuroinflammation and cognitive impairment via Nrf2/NF-κB transcriptional pathway

(2017) Beita Zhao et al.   FOOD AND CHEMICAL TOXICOLOGY

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutations in TrkA Causing Congenital Insensitivity to Pain with Anhidrosis (CIPA) Induce Misfolding, Aggregation, and Mutation-dependent Neurodegeneration by Dysfunction of the Autophagic Flux

(2016) María Luisa Franco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of melatonin on cognitive impairment and hippocampal neuronal damage in a rat model of chronic cerebral hypoperfusion

(2016) CHOONG HYUN LEE et al.   Experimental and Therapeutic Medicine

Central nervous system-specific knockout of Brg1 causes growth retardation and neuronal degeneration

(2015) Li Deng et al.   BRAIN RESEARCH

Overexpression of NTRK1 Promotes Differentiation of Neural Stem Cells into Cholinergic Neurons

(2015) Limin Wang et al.   Biomed Research International

Cholinergic activation of hippocampal neural stem cells in aged dentate gyrus

(2010) Yoshie Itou et al.   HIPPOCAMPUS

Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells

(2009) Chunhui Li et al.   JOURNAL OF NEUROCHEMISTRY