Epigenome-wide association study of peripheral immune cell populations in Parkinson’s disease

Epigenetic modification in Parkinson’s disease

(2023) Hao Song et al.   Frontiers in Cell and Developmental Biology

Linking environmental risk factors with epigenetic mechanisms in Parkinson’s disease

(2023) Maria Tsalenchuk et al.   npj Parkinsons Disease

Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain

(2022) Enquan Xu et al.   Molecular Neurodegeneration

Epigenome-Wide Analysis of DNA Methylation in Parkinson’s Disease Cortex

(2022) Oliver Kaut et al.   Life-Basel

Association of a common genetic variant with Parkinson’s disease is mediated by microglia

(2022) Rebekah G. Langston et al.   Science Translational Medicine

The immunology of Parkinson’s disease

(2022) Biqing Zhu et al.   Seminars in Immunopathology

The IFN-γ-related long non-coding RNA signature predicts prognosis and indicates immune microenvironment infiltration in uterine corpus endometrial carcinoma

(2022) Chunyan Gu et al.   Frontiers in Oncology

Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology

(2022) Lasse Pihlstrøm et al.   Nature Communications

Parkinson’s disease-associated, sex-specific changes in DNA methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2β), and NR4A2 (NURR1) in cortical neurons

(2022) Joseph Kochmanski et al.   npj Parkinsons Disease

DNA methylation predicts the outcome of COVID-19 patients with acute respiratory distress syndrome

(2022) Martina Bradic et al.   Journal of Translational Medicine

Heritability Enrichment Implicates Microglia in Parkinson's Disease Pathogenesis

(2021) Maren Stolp Andersen et al.   ANNALS OF NEUROLOGY

Epigenome-wide association study of COVID-19 severity with respiratory failure

(2021) Manuel Castro de Moura et al.   EBioMedicine

Sex-specific DNA methylation differences in Alzheimer’s disease pathology

(2021) Lanyu Zhang et al.   Acta Neuropathologica Communications

Progress towards therapies for disease modification in Parkinson's disease

(2021) Nirosen Vijiaratnam et al.   LANCET NEUROLOGY

Epigenome-wide association studies: current knowledge, strategies and recommendations

(2021) Maria Pia Campagna et al.   Clinical Epigenetics

Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease

(2020) Costanza L. Vallerga et al.   Nature Communications

Parkinson disease and the immune system — associations, mechanisms and therapeutics

(2020) Eng-King Tan et al.   Nature Reviews Neurology

Epigenomic analysis of Parkinson’s disease neurons identifies Tet2 loss as neuroprotective

(2020) Lee L. Marshall et al.   NATURE NEUROSCIENCE

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

(2020) Changyoun Kim et al.   Science Translational Medicine

Prioritizing Parkinson’s disease genes using population-scale transcriptomic data

(2019) Yang I. Li et al.   Nature Communications

DNA methylation changes associated with Parkinson’s disease progression: outcomes from the first longitudinal genome-wide methylation analysis in blood

(2019) Adrienne Henderson-Smith et al.   Epigenetics

Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

(2019) Georgina Mansell et al.   BMC GENOMICS

pwrEWAS: a user-friendly tool for comprehensive power estimation for epigenome wide association studies (EWAS)

(2019) Stefan Graw et al.   BMC BIOINFORMATICS

Advances in epigenetics link genetics to the environment and disease

(2019) Giacomo Cavalli et al.   NATURE

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

(2019) Mike A Nalls et al.   LANCET NEUROLOGY

The emerging role of Rab GTPases in the pathogenesis of Parkinson's disease

(2018) Yujing Gao et al.   MOVEMENT DISORDERS

Genetic risk for Alzheimer’s disease is concentrated in specific macrophage and microglial transcriptional networks

(2018) Katherine E. Tansey et al.   Genome Medicine

A Systematic Review and Meta-Analysis of Alpha Synuclein Auto-Antibodies in Parkinson's Disease

(2018) Kirsten M. Scott et al.   Frontiers in Neurology

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

(2017) David Sulzer et al.   NATURE

The emerging field of epigenetics in neurodegeneration and neuroprotection

(2017) Jee-Yeon Hwang et al.   NATURE REVIEWS NEUROSCIENCE

Parkinson’s disease is associated with DNA methylation levels in human blood and saliva

(2017) Yu-Hsuan Chuang et al.   Genome Medicine

Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer’s disease

(2017) Qiongshi Lu et al.   PLoS Genetics

Integrated analysis of long non-coding RNA-associated ceRNA network reveals potential lncRNA biomarkers in human lung adenocarcinoma

(2016) Jing Sui et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases

(2016) Sarah A. Gagliano et al.   Annals of Clinical and Translational Neurology

Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients

(2015) Steve Horvath et al.   Aging-US

missMethyl: an R package for analyzing data from Illumina’s HumanMethylation450 platform

(2015) Belinda Phipson et al.   BIOINFORMATICS

CpGFilter: model-based CpG probe filtering with replicates for epigenome-wide association studies

(2015) Jun Chen et al.   BIOINFORMATICS

L-dopa increasesα-synuclein DNA methylation in Parkinson's disease patientsin vivoandin vitro

(2015) Ina Schmitt et al.   MOVEMENT DISORDERS

MDS clinical diagnostic criteria for Parkinson's disease

(2015) Ronald B. Postuma et al.   MOVEMENT DISORDERS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

Epigenome-Wide Association Study for Parkinson’s Disease

(2014) Kerry Moore et al.   NEUROMOLECULAR MEDICINE

LRRK2 Transport Is Regulated by Its Novel Interacting Partner Rab32

(2014) Dieter Waschbüsch et al.   PLoS One

Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

(2014) T. Raj et al.   SCIENCE

A data-driven approach to preprocessing Illumina 450K methylation array data

(2013) Ruth Pidsley et al.   BMC GENOMICS

Distinctive patterns of DNA methylation associated with Parkinson disease

(2013) Eliezer Masliah et al.   Epigenetics

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

Reduced T helper and B lymphocytes in Parkinson's disease

(2012) Claire H. Stevens et al.   JOURNAL OF NEUROIMMUNOLOGY

Selection of reliable reference genes during THP-1 monocyte differentiation into macrophages

(2011) Marten B Maeß et al.   BMC MOLECULAR BIOLOGY

Asymptotic Conditional Singular Value Decomposition for High-Dimensional Genomic Data

(2010) Jeffrey T. Leek   BIOMETRICS

Gene expression results in lipopolysaccharide-stimulated monocytes depend significantly on the choice of reference genes.

(2010) Armin P. Piehler et al.   BMC IMMUNOLOGY

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

(2010) Taye H Hamza et al.   NATURE GENETICS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols