Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice

Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis

(2016) Zhongwei Cao et al.   NATURE MEDICINE

Infection of mice with influenza A/WSN/33 (H1N1) virus alters alveolar type II cell phenotype

(2015) Christian C. Hofer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Lung-Specific Loss of α3 Laminin Worsens Bleomycin-Induced Pulmonary Fibrosis

(2015) Luisa I. Morales-Nebreda et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Activation of Type II Cells into Regenerative Stem Cell Antigen-1+Cells during Alveolar Repair

(2015) Yuru Liu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Fibroblast Growth Factor 2 Is Required for Epithelial Recovery, but Not for Pulmonary Fibrosis, in Response to Bleomycin

(2015) Robert D. Guzy et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice

(2015) Yingying Dong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration

(2015) Shahin Rafii et al.   NATURE CELL BIOLOGY

Telomere dysfunction causes alveolar stem cell failure

(2015) Jonathan K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis

(2014) Joo-Hyeon Lee et al.   CELL

Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

(2014) Brigid L.M. Hogan et al.   Cell Stem Cell

Blockade of IL-6TransSignaling Attenuates Pulmonary Fibrosis

(2014) Thanh-Thuy T. Le et al.   JOURNAL OF IMMUNOLOGY

Alveolar progenitor and stem cells in lung development, renewal and cancer

(2014) Tushar J. Desai et al.   NATURE

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

(2014) Andrew E. Vaughan et al.   NATURE

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

(2014) Barbara Treutlein et al.   NATURE

Lung regeneration: mechanisms, applications and emerging stem cell populations

(2014) Darrell N Kotton et al.   NATURE MEDICINE

IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells

(2014) T. Tadokoro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin 6 Mediates the Therapeutic Effects of Adipose-Derived Stromal/Stem Cells in Lipopolysaccharide-Induced Acute Lung Injury

(2014) Shijia Zhang et al.   STEM CELLS

Type 2 alveolar cells are stem cells in adult lung

(2013) Christina E. Barkauskas et al.   JOURNAL OF CLINICAL INVESTIGATION

A macrophage subpopulation recruited by CC chemokine ligand-2 clears apoptotic cells in noninfectious lung injury

(2012) Jiurong Liang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

(2012) Robert J. J. O'Donoghue et al.   EMBO Molecular Medicine

Toll-like Receptor 4 Is Expressed on Intestinal Stem Cells and Regulates Their Proliferation and Apoptosis via the p53 Up-regulated Modulator of Apoptosis

(2012) Matthew D. Neal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pulmonary fibrosis: patterns and perpetrators

(2012) Paul W. Noble et al.   JOURNAL OF CLINICAL INVESTIGATION

Airway Epithelial Progenitors Are Region Specific and Show Differential Responses to Bleomycin-Induced Lung Injury

(2012) Huaiyong Chen et al.   STEM CELLS

Unsuspected effects of a lung-specific cre deleter mouse line

(2011) Lucie Jeannotte et al.   GENESIS

Role of hyaluronan and hyaluronan-binding proteins in human asthma

(2011) Jiurong Liang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

(2011) Harold A. Chapman et al.   JOURNAL OF CLINICAL INVESTIGATION

Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice

(2011) Keunhee Oh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44

(2011) Yuejuan Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hyaluronan as an Immune Regulator in Human Diseases

(2011) Dianhua Jiang et al.   PHYSIOLOGICAL REVIEWS

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Arrestin Deficiency Protects Against Pulmonary Fibrosis in Mice and Prevents Fibroblast Invasion of Extracellular Matrix

(2011) A. K. Lovgren et al.   Science Translational Medicine

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

(2010) Dianhua Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

HTII-280, a Biomarker Specific to the Apical Plasma Membrane of Human Lung Alveolar Type II Cells

(2010) Robert F. Gonzalez et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb

(2009) K. Matsumoto et al.   DEVELOPMENT