Manifestations of Liver Impairment and the Effects of MH-76, a Non-Quinazoline α1-Adrenoceptor Antagonist, and Prazosin on Liver Tissue in Fructose-Induced Metabolic Syndrome

Pathophysiology of obesity and its associated diseases

(2023) Xin Jin et al.   Acta Pharmaceutica Sinica B

Mechanisms Linking Metabolic-Associated Fatty Liver Disease (MAFLD) to Cardiovascular Disease

(2023) Olufunto O. Badmus et al.   CURRENT HYPERTENSION REPORTS

Association of Inflammatory Cytokines With Non-Alcoholic Fatty Liver Disease

(2022) Yamei Duan et al.   Frontiers in Immunology

Adipose tissue and insulin resistance in obese

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Role of Insulin Resistance in MAFLD

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Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)—A Condition Associated with Heightened Sympathetic Activation

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The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-19

(2021) Liam Rose et al.   Frontiers in Medicine

MH-76, a Novel Non-Quinazoline α1-Adrenoceptor Antagonist, but Not Prazosin Reduces Inflammation and Improves Insulin Signaling in Adipose Tissue of Fructose-Fed Rats

(2021) Monika Kubacka et al.   Pharmaceuticals

Imbalanced GSH/ROS and sequential cell death

(2021) Ting Liu et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

α-1 Adrenergic receptor antagonist doxazosin reverses hepatic stellate cells activation via induction of senescence

(2021) Sandra A. Serna-Salas et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Metabolic-Associated Fatty Liver Disease (MAFLD), Diabetes, and Cardiovascular Disease: Associations with Fructose Metabolism and Gut Microbiota

(2021) Karolina Drożdż et al.   Nutrients

The Contribution of Dietary Fructose to Non-alcoholic Fatty Liver Disease

(2021) Siyu Yu et al.   Frontiers in Pharmacology

Histamine H3 Receptor Ligands—KSK-59 and KSK-73—Reduce Body Weight Gain in a Rat Model of Excessive Eating

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α2-Adrenergic Receptor in Liver Fibrosis: Implications for the Adrenoblocker Mesedin

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Administration of small-molecule guanabenz acetate attenuates fatty liver and hyperglycemia associated with obesity

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Quinazoline alpha-adrenoreceptor blockers as an adjunct cancer treatment: From bench to bedside

(2020) Liam King et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Reversal of cardiac, vascular, and renal dysfunction by non-quinazoline α1-adrenolytics in DOCA-salt hypertensive rats: a comparison with prazosin, a quinazoline-based α1-adrenoceptor antagonist

(2019) Monika Kubacka et al.   HYPERTENSION RESEARCH

The liver as an endocrine organ - linking NAFLD and insulin resistance

(2019) Matthew J Watt et al.   ENDOCRINE REVIEWS

Beneficial effects of non-quinazoline α1-adrenolytics on hypertension and altered metabolism in fructose-fed rats. A comparison with prazosin

(2019) Monika Kubacka et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

The role of thiols in antioxidant systems

(2019) Kathrin Ulrich et al.   FREE RADICAL BIOLOGY AND MEDICINE

The 1,3,5-Triazine Derivatives as Innovative Chemical Family of 5-HT6 Serotonin Receptor Agents with Therapeutic Perspectives for Cognitive Impairment

(2019) Gniewomir Latacz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Hepatic Central Vein: Structure, Fibrosis, and Role in Liver Biology

(2019) Ki M. Mak et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Rodent Models of Nonalcoholic Fatty Liver Disease

(2019) Fang Zhong et al.   DIGESTION

Non-alcoholic fatty liver disease in adults: Current concepts in etiology, outcomes and management

(2019) Thomas Marjot et al.   ENDOCRINE REVIEWS

Dietary Fructose and the Metabolic Syndrome

(2019) Taskinen et al.   Nutrients

High fructose diet-induced metabolic syndrome: Pathophysiological mechanism and treatment by traditional Chinese medicine

(2018) Ying Pan et al.   PHARMACOLOGICAL RESEARCH

Nonalcoholic Fatty Liver Disease in Humans Is Associated with Increased Plasma Endotoxin and Plasminogen Activator Inhibitor 1 Concentrations and with Fructose Intake

(2018) Sabine Thuy et al.   JOURNAL OF NUTRITION

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease

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Effects of Natural Products on Fructose-Induced Nonalcoholic Fatty Liver Disease (NAFLD)

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Combination with Red ginseng and Polygoni Multiflori ameliorates highfructose diet induced metabolic syndrome

(2016) Min Chul Kho et al.   BMC Complementary and Alternative Medicine

Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor β Secretion

(2016) Martin Humberto Muñoz-Ortega et al.   Gut and Liver

Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease

(2016) Manoela Mota et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Doxazosin Stimulates Galectin-3 Expression and Collagen Synthesis in HL-1 Cardiomyocytes Independent of Protein Kinase C Pathway

(2016) Xiaoqian Qian et al.   Frontiers in Pharmacology

Protective effect of crocetin against burn-induced intestinal injury

(2015) Chunxiang Zhou et al.   JOURNAL OF SURGICAL RESEARCH

Effects of acetylsalicylic acid on the levels of sulfane sulfur and non-protein sulfhydryl groups in mouse tissues

(2014) Anna Bilska-Wilkosz et al.   Pharmacological Reports

Effects of Dipeptidyl-Peptidase 4 Inhibitor about Vascular Inflammation in a Metabolic Syndrome Model

(2014) Nicolas F. Renna et al.   PLoS One

Diet high in fructose leads to an overexpression of lipocalin-2 in rat fatty liver

(2014) Salamah Mohammad Alwahsh   WORLD JOURNAL OF GASTROENTEROLOGY

Histopathology of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

(2014) Yoshihisa Takahashi   WORLD JOURNAL OF GASTROENTEROLOGY

Tamarind seed extract mitigates the liver oxidative stress in arthritic rats

(2014) Mahalingam Shanmuga Sundaram et al.   Food & Function

Inflammation, Cytokines and Insulin Resistance: A Clinical Perspective

(2013) Verena Wieser et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Propranolol, a β-adrenoceptor antagonist, worsens liver injury in a model of non-alcoholic steatohepatitis

(2013) Chad McKee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Carvedilol Attenuates the Progression of Alcohol Fatty Liver Disease in Rats

(2012) Jinyao Liu et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Presence and significance of microvesicular steatosis in nonalcoholic fatty liver disease

(2010) Sweta Tandra et al.   JOURNAL OF HEPATOLOGY

Time to re-appraise the role of alpha-1 adrenoceptor antagonists in the management of hypertension?

(2010) Neil Chapman et al.   JOURNAL OF HYPERTENSION

Liver, Muscle, and Adipose Tissue Insulin Action Is Directly Related to Intrahepatic Triglyceride Content in Obese Subjects

(2008) Kevin M. Korenblat et al.   GASTROENTEROLOGY

Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism

(2008) Laia Vilà et al.   HEPATOLOGY

Metabolism of prazosin in rat and characterization of metabolites in plasma, urine, faeces, brain and bile using liquid chromatography/mass spectrometry (LC/MS)

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α1-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice

(2007) L E Randle et al.   BRITISH JOURNAL OF PHARMACOLOGY