Modeling MOG Antibody–Associated Disorder and Neuromyelitis Optica Spectrum Disorder in Animal Models

OCT retinal nerve fiber layer thickness differentiates acute optic neuritis from MOG antibody-associated disease and Multiple Sclerosis

(2022) John J. Chen et al.   Multiple Sclerosis and Related Disorders

Antineonatal Fc Receptor Antibody Treatment Ameliorates MOG-IgG–Associated Experimental Autoimmune Encephalomyelitis

(2022) Jana Remlinger et al.   Neurology-Neuroimmunology & Neuroinflammation

Structure–function correlates of vision loss in neuromyelitis optica spectrum disorders

(2022) Norman K. Gigengack et al.   Scientific Reports

Difference in the Source of Anti-AQP4-IgG and Anti-MOG-IgG Antibodies in CSF in Patients With Neuromyelitis Optica Spectrum Disorder

(2021) Tetsuya Akaishi et al.   NEUROLOGY

The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody

(2020) Romana Höftberger et al.   ACTA NEUROPATHOLOGICA

Comparison of different optomotor response readouts for visual testing in experimental autoimmune encephalomyelitis-optic neuritis

(2020) Christina Hecker et al.   Journal of Neuroinflammation

Differences in morphology and visual function of myelin oligodendrocyte glycoprotein antibody and multiple sclerosis associated optic neuritis

(2020) Rino Vicini et al.   JOURNAL OF NEUROLOGY

c-Jun N-Terminal Kinase as a Therapeutic Target in Experimental Autoimmune Encephalomyelitis

(2020) Maud Bagnoud et al.   Cells

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

(2019) Michael Dietrich et al.   Jove-Journal of Visualized Experiments

Retinal measurements predict 10-year disability in multiple sclerosis

(2019) Alissa Rothman et al.   Annals of Clinical and Translational Neurology

Evidence of Müller Glial Dysfunction in Patients with Aquaporin-4 Immunoglobulin G–Positive Neuromyelitis Optica Spectrum Disorder

(2019) Yuyi You et al.   OPHTHALMOLOGY

Membrane assembly of aquaporin-4 autoantibodies regulates classical complement activation in neuromyelitis optica

(2019) John Soltys et al.   JOURNAL OF CLINICAL INVESTIGATION

Aquaporin-4 IgG seropositivity is associated with worse visual outcomes after optic neuritis than MOG-IgG seropositivity and multiple sclerosis, independent of macular ganglion cell layer thinning

(2019) Elias S Sotirchos et al.   Multiple Sclerosis Journal

Retinal pathology in experimental optic neuritis is characterized by retrograde degeneration and gliosis

(2019) Praveena Manogaran et al.   Acta Neuropathologica Communications

Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis

(2019) Andrés Cruz-Herranz et al.   Journal of Neuroinflammation

Dexras1 Deletion and Iron Chelation Promote Neuroprotection in Experimental Optic Neuritis

(2019) Reas S. Khan et al.   Scientific Reports

Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein

(2018) Melania Spadaro et al.   ANNALS OF NEUROLOGY

Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis

(2018) Yuxin Zhang et al.   EXPERIMENTAL EYE RESEARCH

Exploring experimental autoimmune optic neuritis using multimodal imaging

(2018) Praveena Manogaran et al.   NEUROIMAGE

Sequential phases of RGC axonal and somatic injury in EAE mice examined using DTI and OCT

(2018) Christopher Nishioka et al.   Multiple Sclerosis and Related Disorders

Optical coherence tomography in neuromyelitis optica spectrum disorders: potential advantages for individualized monitoring of progression and therapy

(2017) Frederike C. Oertel et al.   EPMA Journal

Clinicopathological features in anterior visual pathway in neuromyelitis optica

(2016) Mariko Hokari et al.   ANNALS OF NEUROLOGY

Complement-independent retinal pathology produced by intravitreal injection of neuromyelitis optica immunoglobulin G

(2016) Christian M. Felix et al.   Journal of Neuroinflammation

Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4

(2016) Sharon A. Sagan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aquaporin 4-specific T cells and NMO-IgG cause primary retinal damage in experimental NMO/SD

(2016) Bleranda Zeka et al.   Acta Neuropathologica Communications

Radiological differentiation of optic neuritis with myelin oligodendrocyte glycoprotein antibodies, aquaporin-4 antibodies, and multiple sclerosis

(2015) Sudarshini Ramanathan et al.   Multiple Sclerosis Journal

Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography

(2015) JL Bennett et al.   Multiple Sclerosis Journal

Radiological differentiation of optic neuritis with myelin oligodendrocyte glycoprotein antibodies, aquaporin-4 antibodies, and multiple sclerosis

(2015) Sudarshini Ramanathan et al.   Multiple Sclerosis Journal

Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography

(2015) JL Bennett et al.   Multiple Sclerosis Journal

Quantitative Analysis of Mouse Retinal Layers Using Automated Segmentation of Spectral Domain Optical Coherence Tomography Images

(2015) Chantal Dysli et al.   Translational Vision Science & Technology

Pathogenic aquaporin-4 reactive T cells are sufficient to induce mouse model of neuromyelitis optica

(2015) Melina V Jones et al.   Acta Neuropathologica Communications

Neuromyelitis optica: clinical features, immunopathogenesis and treatment

(2014) S. Jarius et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Functional Consequences of Neuromyelitis Optica-IgG Astrocyte Interactions on Blood-Brain Barrier Permeability and Granulocyte Recruitment

(2014) T. Vincent et al.   JOURNAL OF IMMUNOLOGY

Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G

(2014) Nithi Asavapanumas et al.   Journal of Neuroinflammation

Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica

(2013) Julien Ratelade et al.   ACTA NEUROPATHOLOGICA

Passively transferred human NMO-IgG exacerbates demyelination in mouse experimental autoimmune encephalomyelitis

(2013) Harleen Saini et al.   BMC Neurology

Autoantibody depletion ameliorates disease in murine experimental autoimmune encephalomyelitis

(2013) Dilip K. Challa et al.   mAbs

Microcystic Macular Edema

(2013) Mathias Abegg et al.   OPHTHALMOLOGY

Neuromyelitis optica IgG and natural killer cells produce NMO lesions in mice without myelin loss

(2012) Julien Ratelade et al.   ACTA NEUROPATHOLOGICA

Intrathecal pathogenic anti–aquaporin-4 antibodies in early neuromyelitis optica

(2009) Jeffrey L. Bennett et al.   ANNALS OF NEUROLOGY

Antibodies to native myelin oligodendrocyte glycoprotein in children with inflammatory demyelinating central nervous system disease

(2009) Fabienne Brilot et al.   ANNALS OF NEUROLOGY

Neuromyelitis optica: Passive transfer to rats by human immunoglobulin

(2009) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS