Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G

C1q-targeted monoclonal antibody prevents complement-dependent cytotoxicity and neuropathology in in vitro and mouse models of neuromyelitis optica

(2013) Puay-Wah Phuan et al.   ACTA NEUROPATHOLOGICA

Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica

(2013) Julien Ratelade et al.   ACTA NEUROPATHOLOGICA

Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

(2013) Tatsuro Misu et al.   ACTA NEUROPATHOLOGICA

Eosinophil pathogenicity mechanisms and therapeutics in neuromyelitis optica

(2013) Hua Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical Efficacy of Plasmapheresis in Patients with Neuromyelitis Optica Spectrum Disorder and Effects on Circulating Anti-Aquaporin-4 Antibody Levels

(2013) Su-Hyun Kim et al.   Journal of Clinical Neurology

Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study

(2013) Sean J Pittock et al.   LANCET NEUROLOGY

In vivo identification of morphologic retinal abnormalities in neuromyelitis optica

(2013) E. S. Sotirchos et al.   NEUROLOGY

Microcystic Inner Nuclear Layer Abnormalities and Neuromyelitis Optica

(2013) Jeffrey M. Gelfand et al.   JAMA Neurology

Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognizeClostridiumABC transporter

(2012) Michel Varrin-Doyer et al.   ANNALS OF NEUROLOGY

Complement-dependent Cytotoxicity in Neuromyelitis Optica Requires Aquaporin-4 Protein Assembly in Orthogonal Arrays

(2012) Puay-Wah Phuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Current concept of neuromyelitis optica (NMO) and NMO spectrum disorders

(2012) A. Jacob et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Aquaporin 4 and neuromyelitis optica

(2012) Marios C Papadopoulos et al.   LANCET NEUROLOGY

Rituximab dosing and monitoring strategies in neuromyelitis optica patients: creating strategies for therapeutic success

(2012) Benjamin M Greenberg et al.   Multiple Sclerosis Journal

Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms

(2011) Hua Zhang et al.   ANNALS OF NEUROLOGY

Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica

(2011) Lukmanee Tradtrantip et al.   ANNALS OF NEUROLOGY

Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

(2011) Samira Saadoun et al.   ANNALS OF NEUROLOGY

Binding Affinity and Specificity of Neuromyelitis Optica Autoantibodies to Aquaporin-4 M1/M23 Isoforms and Orthogonal Arrays

(2011) Jonathan M. Crane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoimmunity in neuromyelitis optica and opticospinal multiple sclerosis: Astrocytopathy as a common denominator in demyelinating disorders

(2011) Jun-ichi Kira   JOURNAL OF THE NEUROLOGICAL SCIENCES

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice

(2010) Samira Saadoun et al.   BRAIN

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

(2010) Gregory L. Moore et al.   mAbs

AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance

(2010) Sven Jarius et al.   Nature Reviews Neurology

Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo

(2009) Monika Bradl et al.   ANNALS OF NEUROLOGY

Intrathecal pathogenic anti–aquaporin-4 antibodies in early neuromyelitis optica

(2009) Jeffrey L. Bennett et al.   ANNALS OF NEUROLOGY

Neuromyelitis optica: Passive transfer to rats by human immunoglobulin

(2009) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cytotoxic effect of neuromyelitis optica antibody (NMO-IgG) to astrocytes: An in vitro study

(2009) Lidia Sabater et al.   JOURNAL OF NEUROIMMUNOLOGY

Distinctive retinal nerve fibre layer and vascular changes in neuromyelitis optica following optic neuritis

(2009) A J Green et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Expression of multiple AQP4 pools in the plasma membrane and their association with the dystrophin complex

(2008) Grazia Paola Nicchia et al.   JOURNAL OF NEUROCHEMISTRY