Precise small-molecule recognition of a toxic CUG RNA repeat expansion

Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs

(2016) Matthew D. Disney et al.   ACS Chemical Biology

Design of a small molecule against an oncogenic noncoding RNA

(2016) Sai Pradeep Velagapudi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Riboswitch-Binding Flavin Analog That Protects Mice against Clostridium difficile Infection without Inhibiting Cecal Flora

(2015) Kenneth F. Blount et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inhibition of Non-ATG Translational Events in Cells via Covalent Small Molecules Targeting RNA

(2015) Wang-Yong Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective small-molecule inhibition of an RNA structural element

(2015) John A. Howe et al.   NATURE

Short antisense-locked nucleic acids (all-LNAs) correct alternative splicing abnormalities in myotonic dystrophy

(2015) Agnieszka Wojtkowiak-Szlachcic et al.   NUCLEIC ACIDS RESEARCH

A Toxic RNA Catalyzes the In Cellulo Synthesis of Its Own Inhibitor

(2014) Suzanne G. Rzuczek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sequence-based design of bioactive small molecules that target precursor microRNAs

(2014) Sai Pradeep Velagapudi et al.   Nature Chemical Biology

Features of Modularly Assembled Compounds That Impart Bioactivity Against an RNA Target

(2013) Suzanne G. Rzuczek et al.   ACS Chemical Biology

Covalent Small-Molecule-RNA Complex Formation Enables Cellular Profiling of Small-Molecule-RNA Interactions

(2013) Lirui Guan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat–containing RNA

(2013) Rita L Strack et al.   NATURE METHODS

Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules

(2013) Jessica L. Childs-Disney et al.   Nature Communications

Rationally Designed Small Molecules Targeting the RNA That Causes Myotonic Dystrophy Type 1 Are Potently Bioactive

(2012) Jessica L. Childs-Disney et al.   ACS Chemical Biology

Two high-throughput screening assays for aberrant RNA–protein interactions in myotonic dystrophy type 1

(2012) Catherine Z. Chen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins

(2012) Eric T. Wang et al.   CELL

RNA imaging in situ

(2012) Monya Baker   NATURE METHODS

RNA Mimics of Green Fluorescent Protein

(2011) J. S. Paige et al.   SCIENCE

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

(2011) Irina M. Shapiro et al.   PLoS Genetics

Selective silencing of mutated mRNAs in DM1 by using modified hU7-snRNAs

(2010) Virginie François et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rational and Modular Design of Potent Ligands Targeting the RNA That Causes Myotonic Dystrophy 2

(2009) Melissa M. Lee et al.   ACS Chemical Biology

Rational Design of Ligands Targeting Triplet Repeating Transcripts That Cause RNA Dominant Disease: Application to Myotonic Muscular Dystrophy Type 1 and Spinocerebellar Ataxia Type 3

(2009) Alexei Pushechnikov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pentamidine reverses the splicing defects associated with myotonic dystrophy

(2009) M. B. Warf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversal of RNA Dominance by Displacement of Protein Sequestered on Triplet Repeat RNA

(2009) T. M. Wheeler et al.   SCIENCE