Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules
Published 2013 View Full Article
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Title
Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules
Authors
Keywords
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Journal
Nature Communications
Volume 4, Issue 1, Pages -
Publisher
Springer Nature
Online
2013-06-28
DOI
10.1038/ncomms3044
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Related references
Note: Only part of the references are listed.- Rational Design of Bioactive, Modularly Assembled Aminoglycosides Targeting the RNA that Causes Myotonic Dystrophy Type 1
- (2012) Jessica L. Childs-Disney et al. ACS Chemical Biology
- Rationally Designed Small Molecules Targeting the RNA That Causes Myotonic Dystrophy Type 1 Are Potently Bioactive
- (2012) Jessica L. Childs-Disney et al. ACS Chemical Biology
- Chemical Correction of Pre-mRNA Splicing Defects Associated with Sequestration of Muscleblind-like 1 Protein by Expanded r(CAG)-Containing Transcripts
- (2012) Amit Kumar et al. ACS Chemical Biology
- Two high-throughput screening assays for aberrant RNA–protein interactions in myotonic dystrophy type 1
- (2012) Catherine Z. Chen et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins
- (2012) Eric T. Wang et al. CELL
- Design of a Bioactive Small Molecule That Targets the Myotonic Dystrophy Type 1 RNA via an RNA Motif–Ligand Database and Chemical Similarity Searching
- (2012) Raman Parkesh et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy
- (2012) Konstantinos Charizanis et al. NEURON
- RNA Splicing Is Responsive to MBNL1 Dose
- (2012) Sonali P. Jog et al. PLoS One
- Myotonic Dystrophy Type 1 RNA Crystal Structures Reveal Heterogeneous 1 × 1 Nucleotide UU Internal Loop Conformations
- (2011) Amit Kumar et al. BIOCHEMISTRY
- NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)2Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1
- (2011) Raman Parkesh et al. BIOCHEMISTRY
- Small-Molecule Inhibitors of the TLR3/dsRNA Complex
- (2011) Kui Cheng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy
- (2011) Charlotte Fugier et al. NATURE MEDICINE
- CAG repeats mimic CUG repeats in the misregulation of alternative splicing
- (2011) Agnieszka Mykowska et al. NUCLEIC ACIDS RESEARCH
- Emerging Applications of Riboswitches in Chemical Biology
- (2010) Shana Topp et al. ACS Chemical Biology
- Alternative splicing dysregulation secondary to skeletal muscle regeneration
- (2010) James P. Orengo et al. ANNALS OF NEUROLOGY
- Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients
- (2010) Chantal Sellier et al. EMBO JOURNAL
- The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy
- (2010) Simona Pedrotti et al. EMBO JOURNAL
- Novel Inhibitors of Dengue Virus Methyltransferase: Discovery by in Vitro-Driven Virtual Screening on a Desktop Computer Grid
- (2010) Michael Podvinec et al. JOURNAL OF MEDICINAL CHEMISTRY
- Reprogramming bacteria to seek and destroy an herbicide
- (2010) Joy Sinha et al. Nature Chemical Biology
- Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy
- (2010) Hongqing Du et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Reprogramming Cellular Behavior with RNA Controllers Responsive to Endogenous Proteins
- (2010) S. J. Culler et al. SCIENCE
- Rational and Modular Design of Potent Ligands Targeting the RNA That Causes Myotonic Dystrophy 2
- (2009) Melissa M. Lee et al. ACS Chemical Biology
- Splice site strength–dependent activity and genetic buffering by poly-G runs
- (2009) Xinshu Xiao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Pentamidine reverses the splicing defects associated with myotonic dystrophy
- (2009) M. B. Warf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1
- (2008) Marianna Teplova et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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