Algorithmic fairness in artificial intelligence for medicine and healthcare

Biased data, biased AI: deep networks predict the acquisition site of TCGA images

(2023) Taher Dehkharghanian et al.   Diagnostic Pathology

Algorithmic encoding of protected characteristics in chest X-ray disease detection models

(2023) Ben Glocker et al.   EBioMedicine

Uncovering expression signatures of synergistic drug responses via ensembles of explainable machine-learning models

(2023) Joseph D. Janizek et al.   Nature Biomedical Engineering

Evaluation of domain generalization and adaptation on improving model robustness to temporal dataset shift in clinical medicine

(2022) Lin Lawrence Guo et al.   Scientific Reports

Peeking into a black box, the fairness and generalizability of a MIMIC-III benchmarking model

(2022) Eliane Röösli et al.   Scientific Data

Deep learning-enabled assessment of cardiac allograft rejection from endomyocardial biopsies

(2022) Jana Lipkova et al.   NATURE MEDICINE

FAIR: Fair adversarial instance re-weighting

(2022) Andrija Petrović et al.   NEUROCOMPUTING

Interpretability and fairness evaluation of deep learning models on MIMIC-IV dataset

(2022) Chuizheng Meng et al.   Scientific Reports

Racial and Ethnic Differences in Hysterectomy-Corrected Uterine Corpus Cancer Mortality by Stage and Histologic Subtype

(2022) Megan A. Clarke et al.   JAMA Oncology

Detection of signs of disease in external photographs of the eyes via deep learning

(2022) Boris Babenko et al.   Nature Biomedical Engineering

Pan-cancer integrative histology-genomic analysis via multimodal deep learning

(2022) Richard J. Chen et al.   CANCER CELL

Wasserstein-based fairness interpretability framework for machine learning models

(2022) Alexey Miroshnikov et al.   MACHINE LEARNING

Reply to: ‘Potential sources of dataset bias complicate investigation of underdiagnosis by machine learning algorithms’ and ‘Confounding factors need to be accounted for in assessing bias by machine learning algorithms’

(2022) Laleh Seyyed-Kalantari et al.   NATURE MEDICINE

Potential sources of dataset bias complicate investigation of underdiagnosis by machine learning algorithms

(2022) Mélanie Bernhardt et al.   NATURE MEDICINE

Confounding factors need to be accounted for in assessing bias by machine learning algorithms

(2022) Pritam Mukherjee et al.   NATURE MEDICINE

Disparities in dermatology AI performance on a diverse, curated clinical image set

(2022) Roxana Daneshjou et al.   Science Advances

African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent

(2022) Rachel Martini et al.   Cancer Discovery

Racial and Ethnic Health Disparities Related to COVID-19

(2021) Leo Lopez et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

An algorithmic approach to reducing unexplained pain disparities in underserved populations

(2021) Emma Pierson et al.   NATURE MEDICINE

Race and Genetic Ancestry in Medicine — A Time for Reckoning with Racism

(2021) Luisa N. Borrell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Federated Learning of Electronic Health Records to Improve Mortality Prediction in Hospitalized Patients With COVID-19: Machine Learning Approach

(2021) Akhil Vaid et al.   JMIR Medical Informatics

Association of the Estimated Glomerular Filtration Rate With vs Without a Coefficient for Race With Time to Eligibility for Kidney Transplant

(2021) Leila R. Zelnick et al.   JAMA Network Open

Social Determinants of Health and Race Disparities in Kidney Transplant

(2021) Hannah Wesselman et al.   Clinical Journal of the American Society of Nephrology

Embracing Genetic Diversity to Improve Black Health

(2021) Akinyemi Oni-Orisan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human-interpretable image features derived from densely mapped cancer pathology slides predict diverse molecular phenotypes

(2021) James A. Diao et al.   Nature Communications

A patient-centric dataset of images and metadata for identifying melanomas using clinical context

(2021) Veronica Rotemberg et al.   Scientific Data

Addressing Artificial Intelligence Bias in Retinal Diagnostics

(2021) Philippe Burlina et al.   Translational Vision Science & Technology

Data-efficient and weakly supervised computational pathology on whole-slide images

(2021) Ming Y. Lu et al.   Nature Biomedical Engineering

A unified framework for cross-population trait prediction by leveraging the genetic correlation of polygenic traits

(2021) Mingxuan Cai et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Breast cancer disparities in outcomes; unmasking biological determinants associated with racial and genetic diversity

(2021) Rachel Martini et al.   CLINICAL & EXPERIMENTAL METASTASIS

Removing Race From Kidney Function Estimates

(2021) Anna C. van der Burgh et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Removing Race From Kidney Function Estimates—Reply

(2021) James A. Diao et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Federated semi-supervised learning for COVID region segmentation in chest CT using multi-national data from China, Italy, Japan

(2021) Dong Yang et al.   MEDICAL IMAGE ANALYSIS

AI-based pathology predicts origins for cancers of unknown primary

(2021) Ming Y. Lu et al.   NATURE

The Pathophysiology of Racial Disparities

(2021) Amanda Calhoun   NEW ENGLAND JOURNAL OF MEDICINE

Learning models with uniform performance via distributionally robust optimization

(2021) John C. Duchi et al.   ANNALS OF STATISTICS

FairLens: Auditing black-box clinical decision support systems

(2021) Cecilia Panigutti et al.   INFORMATION PROCESSING & MANAGEMENT

Race-Free Equations for eGFR: Comparing Effects on CKD Classification

(2021) James A. Diao et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Automatic detection of 39 fundus diseases and conditions in retinal photographs using deep neural networks

(2021) Ling-Ping Cen et al.   Nature Communications

The impact of site-specific digital histology signatures on deep learning model accuracy and bias

(2021) Frederick M. Howard et al.   Nature Communications

Systematic Review of Approaches to Preserve Machine Learning Performance in the Presence of Temporal Dataset Shift in Clinical Medicine

(2021) Lin Lawrence Guo et al.   Applied Clinical Informatics

Sex-Specific Differences in Glioblastoma

(2021) Anna Carrano et al.   Cells

Association of Inclusion of More Black Individuals in Lung Cancer Screening With Reduced Mortality

(2021) Ashley E. Prosper et al.   JAMA Network Open

Privacy-first health research with federated learning

(2021) Adam Sadilek et al.   npj Digital Medicine

Nonhormone-Related Histologic Findings in Postsurgical Pathology Specimens From Transgender Persons

(2021) Archan Kakadekar et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Learning to Disentangle Inter-Subject Anatomical Variations in Electrocardiographic Data

(2021) Prashnna K. Gyawali et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Thirty years of the International Banff Classification for Allograft Pathology: the past, present, and future of kidney transplant diagnostics

(2021) Alexandre Loupy et al.   KIDNEY INTERNATIONAL

Federated learning for computational pathology on gigapixel whole slide images

(2021) Ming Y. Lu et al.   MEDICAL IMAGE ANALYSIS

Underdiagnosis bias of artificial intelligence algorithms applied to chest radiographs in under-served patient populations

(2021) Laleh Seyyed-Kalantari et al.   NATURE MEDICINE

Computationally Derived Image Signature of Stromal Morphology Is Prognostic of Prostate Cancer Recurrence Following Prostatectomy in African American Patients

(2020) Hersh K. Bhargava et al.   CLINICAL CANCER RESEARCH

KDIGO Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation

(2020) Steven J. Chadban et al.   TRANSPLANTATION

Hidden in Plain Sight — Reconsidering the Use of Race Correction in Clinical Algorithms

(2020) Darshali A. Vyas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Benchmarking machine learning models on multi-centre eICU critical care dataset

(2020) Seyedmostafa Sheikhalishahi et al.   PLoS One

Causality matters in medical imaging

(2020) Daniel C. Castro et al.   Nature Communications

Federated learning in medicine: facilitating multi-institutional collaborations without sharing patient data

(2020) Micah J. Sheller et al.   Scientific Reports

Cancer health disparities in racial/ethnic minorities in the United States

(2020) Valentina A. Zavala et al.   BRITISH JOURNAL OF CANCER

Multi-site fMRI analysis using privacy-preserving federated learning and domain adaptation: ABIDE results

(2020) Xiaoxiao Li et al.   MEDICAL IMAGE ANALYSIS

Don’t ignore genetic data from minority populations

(2020) Chief Ben-Eghan et al.   NATURE

Atezolizumab for First-Line Treatment of PD-L1–Selected Patients with NSCLC

(2020) Roy S. Herbst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Racial Differences in Genomic Profiling of Prostate Cancer

(2020) Brandon A. Mahal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Racial disparities, FRAX, and the care of patients with osteoporosis

(2020) E.M. Lewiecki et al.   OSTEOPOROSIS INTERNATIONAL

Ethical and Legal Challenges of Artificial Intelligence in Nuclear Medicine

(2020) Geoffrey Currie et al.   SEMINARS IN NUCLEAR MEDICINE

Association of Race With Mortality Among Patients Hospitalized With Coronavirus Disease 2019 (COVID-19) at 92 US Hospitals

(2020) Baligh R. Yehia et al.   JAMA Network Open

Deep learning in cancer pathology: a new generation of clinical biomarkers

(2020) Amelie Echle et al.   BRITISH JOURNAL OF CANCER

An empirical characterization of fair machine learning for clinical risk prediction

(2020) Stephen R. Pfohl et al.   JOURNAL OF BIOMEDICAL INFORMATICS

A framework for making predictive models useful in practice

(2020) Kenneth Jung et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

DeepTFactor: A deep learning-based tool for the prediction of transcription factors

(2020) Gi Bae Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Federated learning improves site performance in multicenter deep learning without data sharing

(2020) Karthik V Sarma et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Sex differences in GBM revealed by analysis of patient imaging, transcriptome, and survival data

(2019) Wei Yang et al.   Science Translational Medicine

Clinical use of current polygenic risk scores may exacerbate health disparities

(2019) Alicia R. Martin et al.   NATURE GENETICS

Federated discovery and sharing of genomic data using Beacons

(2019) Marc Fiume et al.   NATURE BIOTECHNOLOGY

Attention gated networks: Learning to leverage salient regions in medical images

(2019) Jo Schlemper et al.   MEDICAL IMAGE ANALYSIS

Reconsidering the Consequences of Using Race to Estimate Kidney Function

(2019) Nwamaka Denise Eneanya et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

(2019) Jakob Nikolas Kather et al.   NATURE MEDICINE

Clinical-grade computational pathology using weakly supervised deep learning on whole slide images

(2019) Gabriele Campanella et al.   NATURE MEDICINE

Analysis of polygenic risk score usage and performance in diverse human populations

(2019) L. Duncan et al.   Nature Communications

Characterization of frequently mutated cancer genes in Chinese breast tumors: a comparison of Chinese and TCGA cohorts

(2019) Guochun Zhang et al.   Annals of Translational Medicine

The Genomics Research and Innovation Network: creating an interoperable, federated, genomics learning system

(2019) Kenneth D. Mandl et al.   GENETICS IN MEDICINE

Personalized Radiotherapy Design for Glioblastoma: Integrating Mathematical Tumor Models, Multimodal Scans, and Bayesian Inference

(2019) Jana Lipkova et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Patient Clustering Improves Efficiency of Federated Machine Learning to Predict Mortality and Hospital Stay Time Using Distributed Electronic Medical Records

(2019) Li Huang et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Protective Innate Immune Variants in Racial/Ethnic Disparities of Breast and Prostate Cancer

(2019) Susan T. Yeyeodu et al.   Cancer Immunology Research

Commercial Gene Expression Tests for Prostate Cancer Prognosis Provide Paradoxical Estimates of Race-Specific Risk

(2019) Jordan H. Creed et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Comparative genetic architectures of schizophrenia in East Asian and European populations

(2019) Max Lam et al.   NATURE GENETICS

Dissecting racial bias in an algorithm used to manage the health of populations

(2019) Ziad Obermeyer et al.   SCIENCE

Comparison and Modelling of Country-level Microblog User and Activity in Cyber-physical-social Systems Using Weibo and Twitter Data

(2019) Po Yang et al.   ACM Transactions on Intelligent Systems and Technology

Efficient and Privacy-Enhanced Federated Learning for Industrial Artificial Intelligence

(2019) Meng Hao et al.   IEEE Transactions on Industrial Informatics

Robust and Communication-Efficient Federated Learning From Non-i.i.d. Data

(2019) Felix Sattler et al.   IEEE Transactions on Neural Networks and Learning Systems

Beyond Consent: Building Trusting Relationships With Diverse Populations in Precision Medicine Research

(2018) Stephanie A. Kraft et al.   AMERICAN JOURNAL OF BIOETHICS

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

(2018) Jianfang Liu et al.   CELL

Lack Of Diversity In Genomic Databases Is A Barrier To Translating Precision Medicine Research Into Practice

(2018) Latrice G. Landry et al.   HEALTH AFFAIRS

Federated learning of predictive models from federated Electronic Health Records

(2018) Theodora S. Brisimi et al.   INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS

Implementing Machine Learning in Health Care — Addressing Ethical Challenges

(2018) Danton S. Char et al.   NEW ENGLAND JOURNAL OF MEDICINE

The accuracy, fairness, and limits of predicting recidivism

(2018) Julia Dressel et al.   Science Advances

Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning

(2018) Ryan Poplin et al.   Nature Biomedical Engineering

Examining How Race, Ethnicity, and Ancestry Data Are Used in Biomedical Research

(2018) Vence L. Bonham et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The eICU Collaborative Research Database, a freely available multi-center database for critical care research

(2018) Tom J. Pollard et al.   Scientific Data

Explainable machine-learning predictions for the prevention of hypoxaemia during surgery

(2018) Scott M. Lundberg et al.   Nature Biomedical Engineering

Racial-Ethnic Differences in Osteoarthritis Pain and Disability: A Meta-Analysis

(2018) Ivana A. Vaughn et al.   JOURNAL OF PAIN

The Moral Machine experiment

(2018) Edmond Awad et al.   NATURE

Using a Deep Learning Algorithm and Integrated Gradients Explanation to Assist Grading for Diabetic Retinopathy

(2018) Rory Sayres et al.   OPHTHALMOLOGY

A brief history of FRAX

(2018) John A. Kanis et al.   Archives of Osteoporosis

Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer

(2017) Babak Ehteshami Bejnordi et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genomics, Health Disparities, and Missed Opportunities for the Nation’s Research Agenda

(2017) Kathleen McGlone West et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Trends in Opioid-related Inpatient Stays Shifted After the US Transitioned to ICD-10-CM Diagnosis Coding in 2015

(2017) Kevin C. Heslin et al.   MEDICAL CARE

LGBT healthcare disparities: What progress have we made?

(2017) Kathleen A. Bonvicini   PATIENT EDUCATION AND COUNSELING

Exploring the social determinants of racial/ethnic disparities in prenatal care utilization and maternal outcome

(2017) Alexis Gadson et al.   SEMINARS IN PERINATOLOGY

Fair Prediction with Disparate Impact: A Study of Bias in Recidivism Prediction Instruments

(2017) Alexandra Chouldechova   Big Data

Potential US Population Impact of the 2017 ACC/AHA High Blood Pressure Guideline

(2017) Paul Muntner et al.   CIRCULATION

Racial disparities in patient survival and tumor mutation burden, and the association between tumor mutation burden and cancer incidence rate

(2017) Wensheng Zhang et al.   Scientific Reports

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Unsupervised domain adaptation techniques based on auto-encoder for non-stationary EEG-based emotion recognition

(2016) Xin Chai et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Addressing Social Determinants of Health and Health Inequalities

(2016) Nancy E. Adler et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic Misdiagnoses and the Potential for Health Disparities

(2016) Arjun K. Manrai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

(2016) Alexander Gusev et al.   Nature Communications

MIMIC-III, a freely accessible critical care database

(2016) Alistair E.W. Johnson et al.   Scientific Data

Racial/Ethnic Disparities in Genomic Sequencing

(2016) Daniel E. Spratt et al.   JAMA Oncology

Gleason and Fuhrman no longer make the grade

(2015) Brett Delahunt et al.   HISTOPATHOLOGY

The saga of diagnostic/classification criteria in Behcet's disease

(2015) Fereydoun Davatchi et al.   International Journal of Rheumatic Diseases

The CPTAC Data Portal: A Resource for Cancer Proteomics Research

(2015) Nathan J. Edwards et al.   JOURNAL OF PROTEOME RESEARCH

Access Disparity and Health Inequality of the Elderly: Unmet Needs and Delayed Healthcare

(2015) Tetsuji Yamada et al.   International Journal of Environmental Research and Public Health

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

A Prospective, Molecular Epidemiology Study of EGFR Mutations in Asian Patients with Advanced Non–Small-Cell Lung Cancer of Adenocarcinoma Histology (PIONEER)

(2014) Yuankai Shi et al.   Journal of Thoracic Oncology

The Electronic Medical Records and Genomics (eMERGE) Network: past, present and future

(2013) Omri Gottesman et al.   GENETICS IN MEDICINE

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

De-identification Methods for Open Health Data: The Case of the Heritage Health Prize Claims Dataset

(2012) Khaled El Emam et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Strategies for De-identification and Anonymization of Electronic Health Record Data for Use in Multicenter Research Studies

(2012) Clete A. Kushida et al.   MEDICAL CARE

The Age-related Eye Disease Study 2 (AREDS2)

(2012) Emily Y. Chew et al.   OPHTHALMOLOGY

Data preprocessing techniques for classification without discrimination

(2011) Faisal Kamiran et al.   KNOWLEDGE AND INFORMATION SYSTEMS

The landscape of recombination in African Americans

(2011) Anjali G. Hinch et al.   NATURE

Disparities in breast cancer characteristics and outcomes by race/ethnicity

(2010) Siew Loon Ooi et al.   BREAST CANCER RESEARCH AND TREATMENT

The National Lung Screening Trial: Overview and Study Design

(2010)   RADIOLOGY

Population-Based Fracture Risk Assessment and Osteoporosis Treatment Disparities by Race and Gender

(2009) Jeffrey R. Curtis et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

Food Insecurity Is Associated with Chronic Disease among Low-Income NHANES Participants

(2009) Hilary K. Seligman et al.   JOURNAL OF NUTRITION

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

(2009)   NEW ENGLAND JOURNAL OF MEDICINE