Matrix density regulates adipocyte phenotype

A combination of matrix stiffness and degradability dictate microvascular network assembly and remodeling in cell-laden poly(ethylene glycol) hydrogels

(2023) Nicole E. Friend et al.   BIOMATERIALS

The Gene Ontology knowledgebase in 2023

(2023) et al.   GENETICS

Collagens Regulating Adipose Tissue Formation and Functions

(2023) Iida Jääskeläinen et al.   Biomedicines

Relationship of matrix stiffness and cell morphology in regulation of osteogenesis and adipogenesis of BMSCs

(2022) Yutong Guo et al.   MOLECULAR BIOLOGY REPORTS

Mitochondrial respiration is decreased in visceral but not subcutaneous adipose tissue in obese individuals with fatty liver disease

(2022) Kalliopi Pafili et al.   JOURNAL OF HEPATOLOGY

Proteome analysis of human adipocytes identifies depot-specific heterogeneity at metabolic control points

(2021) Arthe Raajendiran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The human type 2 diabetes-specific visceral adipose tissue proteome and transcriptome in obesity

(2021) Nicholas J. Carruthers et al.   Scientific Reports

Tuning Hydrogels by Mixing Dynamic Cross‐Linkers: Enabling Cell‐Instructive Hydrogels and Advanced Bioinks

(2021) Francis L. C. Morgan et al.   Advanced Healthcare Materials

Viscoelastic characterization of diabetic and non-diabetic human adipose tissue

(2020) Benjamin A. Juliar et al.   BIORHEOLOGY

The stiffness of living tissues and its implications for tissue engineering

(2020) Carlos F. Guimarães et al.   Nature Reviews Materials

Gene Expression Profiling of Human Adipose Tissue Stem Cells during 2D versus 3D Adipogenesis

(2020) Fatema Tuj Zohora et al.   CELLS TISSUES ORGANS

Dermatopontin, A Novel Adipokine Promoting Adipose Tissue Extracellular Matrix Remodelling and Inflammation in Obesity

(2020) Xabier Unamuno et al.   Journal of Clinical Medicine

Elucidating nanoscale mechanical properties of diabetic human adipose tissue using atomic force microscopy

(2020) J. K. Wenderott et al.   Scientific Reports

Deciphering the relative roles of matrix metalloproteinase- and plasmin-mediated matrix degradation during capillary morphogenesis using engineered hydrogels

(2019) Jeffrey A. Beamish et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

The Association between Body Composition using Dual energy X-ray Absorptiometry and Type-2 Diabetes: A Systematic Review and Meta-Analysis of Observational studies

(2019) Preeti Gupta et al.   Scientific Reports

Cell-mediated matrix stiffening accompanies capillary morphogenesis in ultra-soft amorphous hydrogels

(2019) Benjamin A. Juliar et al.   BIOMATERIALS

Matrix Stiffness Modulates Mesenchymal Stem Cell Sensitivity to Geometric Asymmetry Signals

(2018) Maria E. Piroli et al.   ANNALS OF BIOMEDICAL ENGINEERING

Mechanically tunable conductive interpenetrating network hydrogels that mimic the elastic moduli of biological tissue

(2018) Vivian R. Feig et al.   Nature Communications

Substrate elasticity regulates adipose-derived stromal cell differentiation towards osteogenesis and adipogenesis through β-catenin transduction

(2018) Jing Xie et al.   Acta Biomaterialia

Regulating osteogenesis and adipogenesis in adipose-derived stem cells by controlling underlying substrate stiffness

(2017) Tao Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Synthetic hydrogels mimicking basement membrane matrices to promote cell-matrix interactions

(2017) Ricardo Cruz-Acuña et al.   MATRIX BIOLOGY

Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated aging and diabetes

(2017) María Gómez-Serrano et al.   Redox Biology

Matrix directed adipogenesis and neurogenesis of mesenchymal stem cells derived from adipose tissue and bone marrow

(2016) Junmin Lee et al.   Acta Biomaterialia

Relevance of omental pericellular adipose tissue collagen in the pathophysiology of human abdominal obesity and related cardiometabolic risk

(2016) A Michaud et al.   INTERNATIONAL JOURNAL OF OBESITY

Direct influence of culture dimensionality on human mesenchymal stem cell differentiation at various matrix stiffnesses using a fibrous self-assembling peptide hydrogel

(2016) Nathaniel J. Hogrebe et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Accumulation and Changes in Composition of Collagens in Subcutaneous Adipose Tissue After Bariatric Surgery

(2016) Yuejun Liu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adipose tissue fibrosis, hypertrophy, and hyperplasia: Correlations with diabetes in human obesity

(2016) Lindsey A. Muir et al.   Obesity

Methacrylated gelatin and mature adipocytes are promising components for adipose tissue engineering

(2015) Birgit Huber et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Association of Adipose Tissue and Liver Fibrosis With Tissue Stiffness in Morbid Obesity: Links With Diabetes and BMI Loss After Gastric Bypass

(2014) Meriem Abdennour et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Human adipocyte function is impacted by mechanical cues

(2014) V Pellegrinelli et al.   JOURNAL OF PATHOLOGY

A Comparison of the Rheologic Properties of an Adipose-Derived Extracellular Matrix Biomaterial, Lipoaspirate, Calcium Hydroxylapatite, and Cross-linked Hyaluronic Acid

(2014) Amit Kochhar et al.   JAMA Facial Plastic Surgery

Time-dependent cellular morphogenesis and matrix stiffening in proteolytically responsive hydrogels

(2013) Dafna Kesselman et al.   Acta Biomaterialia

Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity

(2013) Denise E. Lackey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Stimulation of adipogenesis of adult adipose-derived stem cells using substrates that mimic the stiffness of adipose tissue

(2013) D. Adam Young et al.   BIOMATERIALS

Proteomic analysis of visceral adipose tissue in pre-obese patients with type 2 diabetes

(2013) Mora Murri et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Encapsulation of fibroblasts causes accelerated alginate hydrogel degradation

(2010) N.C. Hunt et al.   Acta Biomaterialia

Fibrosis in Human Adipose Tissue: Composition, Distribution, and Link With Lipid Metabolism and Fat Mass Loss

(2010) A. Divoux et al.   DIABETES

A micromechanical model for the Young’s modulus of adipose tissue

(2010) Kerstyn Comley et al.   INTERNATIONAL JOURNAL OF SOLIDS AND STRUCTURES

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Abdominal Subcutaneous and Visceral Adipose Tissue and Insulin Resistance in the Framingham Heart Study

(2010) Sarah R. Preis et al.   Obesity

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Abdominal Subcutaneous Adipose Tissue: A Protective Fat Depot?

(2009) S. A. Porter et al.   DIABETES CARE

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

(2008) Corneliu Henegar et al.   GENOME BIOLOGY

The Effect of Matrix Density on the Regulation of 3-D Capillary Morphogenesis

(2007) Cyrus M. Ghajar et al.   BIOPHYSICAL JOURNAL