A combination of matrix stiffness and degradability dictate microvascular network assembly and remodeling in cell-laden poly(ethylene glycol) hydrogels

Engineering the multiscale complexity of vascular networks

(2022) Colleen O’Connor et al.   Nature Reviews Materials

Cell‐Laden Gradient Hydrogel Scaffolds for Neovascularization of Engineered Tissues

(2021) Yusheng J. He et al.   Advanced Healthcare Materials

Engineering PEG-based hydrogels to foster efficient endothelial network formation in free-swelling and confined microenvironments

(2020) Alexander Brown et al.   BIOMATERIALS

A modular polymer microbead angiogenesis scaffold to characterize the effects of adhesion ligand density on angiogenic sprouting

(2020) Marianna Sofman et al.   BIOMATERIALS

Injectable pre-cultured tissue modules catalyze the formation of extensive functional microvasculature in vivo

(2020) Nicole E. Friend et al.   Scientific Reports

Mature vessel networks in engineered tissue promote graft–host anastomosis and prevent graft thrombosis

(2019) Shahar Ben-Shaul et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the relative roles of matrix metalloproteinase- and plasmin-mediated matrix degradation during capillary morphogenesis using engineered hydrogels

(2019) Jeffrey A. Beamish et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization

(2019) Timo Rademakers et al.   Journal of Tissue Engineering and Regenerative Medicine

Cell-mediated matrix stiffening accompanies capillary morphogenesis in ultra-soft amorphous hydrogels

(2019) Benjamin A. Juliar et al.   BIOMATERIALS

Immobilized RGD concentration and proteolytic degradation synergistically enhance vascular sprouting within hydrogel scaffolds of varying modulus

(2019) Yusheng J. He et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Protease-Sensitive Hydrogel Biomaterials with Decoupled Modulus and Adhesion Ligand Gradients for 3D Vascular Sprouting

(2018) Yusheng J. He et al.   BIOMACROMOLECULES

Functional Hydrogels With Tunable Structures and Properties for Tissue Engineering Applications

(2018) Xiaomeng Li et al.   Frontiers in Chemistry

Nanoscale physicochemical properties of chain- and step-growth polymerized PEG hydrogels affect cell-material interactions

(2017) Kanika Vats et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

3D-printed vascular networks direct therapeutic angiogenesis in ischaemia

(2017) T. Mirabella et al.   Nature Biomedical Engineering

Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels

(2016) Matthew R. Zanotelli et al.   Acta Biomaterialia

Differential regulation of angiogenesis using degradable VEGF-binding microspheres

(2016) David G. Belair et al.   BIOMATERIALS

Matrix stiffening promotes a tumor vasculature phenotype

(2016) Francois Bordeleau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of the crosslinking kinetics of multi-arm poly(ethylene glycol) hydrogels formed via Michael-type addition

(2016) Jiwon Kim et al.   Soft Matter

Decreasing matrix modulus of PEG hydrogels induces a vascular phenotype in human cord blood stem cells

(2015) Shruthi Mahadevaiah et al.   BIOMATERIALS

Poly(Ethylene Glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells

(2015) Erica B. Peters et al.   Cellular and Molecular Bioengineering

Encoding Hydrogel Mechanics via Network Cross-Linking Structure

(2015) Ryan M. Schweller et al.   ACS Biomaterials-Science & Engineering

Encoding Hydrogel Mechanics via Network Cross-Linking Structure

(2015) Ryan M. Schweller et al.   ACS Biomaterials Science & Engineering

Thiol-norbornene photoclick hydrogels for tissue engineering applications

(2014) Chien-Chi Lin et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Protease-Sensitive PEG Hydrogels Regulate Vascularization In Vitro and In Vivo

(2014) Marina Vigen et al.   MACROMOLECULAR BIOSCIENCE

Evaluation of MMP substrate concentration and specificity for neovascularization of hydrogel scaffolds

(2014) S. Sokic et al.   Biomaterials Science

Comparison of photopolymerizable thiol-ene PEG and acrylate-based PEG hydrogels for cartilage development

(2013) Justine J. Roberts et al.   BIOMATERIALS

Differential effects of cell adhesion, modulus and VEGFR-2 inhibition on capillary network formation in synthetic hydrogel arrays

(2013) Eric H. Nguyen et al.   BIOMATERIALS

MMP-Sensitive PEG Diacrylate Hydrogels with Spatial Variations in Matrix Properties Stimulate Directional Vascular Sprout Formation

(2013) Michael V. Turturro et al.   PLoS One

Cross-Linking and Degradation of Step-Growth Hydrogels Formed by Thiol–Ene Photoclick Chemistry

(2012) Han Shih et al.   BIOMACROMOLECULES

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Controlled Proteolytic Cleavage Site Presentation in Biomimetic PEGDA Hydrogels Enhances Neovascularization In Vitro

(2012) Sonja Sokic et al.   TISSUE ENGINEERING PART A

Stromal Cell Identity Influences the In Vivo Functionality of Engineered Capillary Networks Formed by Co-delivery of Endothelial Cells and Stromal Cells

(2012) Stephanie J. Grainger et al.   TISSUE ENGINEERING PART A

The role of pore size on vascularization and tissue remodeling in PEG hydrogels

(2011) Yu-Chieh Chiu et al.   BIOMATERIALS

Elucidating the Role of Matrix Stiffness in 3D Cell Migration and Remodeling

(2011) M. Ehrbar et al.   BIOPHYSICAL JOURNAL

The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation

(2011) Andrew C. Newman et al.   MOLECULAR BIOLOGY OF THE CELL

Biomimetic hydrogels with pro-angiogenic properties

(2010) James J. Moon et al.   BIOMATERIALS

Bioactive hydrogels made from step-growth derived PEG–peptide macromers

(2010) Jordan S. Miller et al.   BIOMATERIALS

Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering

(2010) Junmin Zhu   BIOMATERIALS

SPARC-derived protease substrates to enhance the plasmin sensitivity of molecularly engineered PEG hydrogels

(2010) J. Patterson et al.   BIOMATERIALS

Serum or Plasma Samples?

(2008) Ferdinando Mannello   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Prevascularization of a Fibrin-Based Tissue Construct Accelerates the Formation of Functional Anastomosis with Host Vasculature

(2008) Xiaofang Chen et al.   TISSUE ENGINEERING PART A