Determination of Gastric Water Emptying in Fasted and Fed State Conditions Using a Compression-Coated Tablet and Salivary Caffeine Kinetics

Comparing Salivary Caffeine Kinetics of 13C and 12C Caffeine for Gastric Emptying of 50 mL Water

(2023) Michael Grimm et al.   Pharmaceutics

Impact of Tablet Size and Shape on the Swallowability in Older Adults

(2023) Henriette Hummler et al.   Pharmaceutics

Intragastric Carbon Dioxide Release Prolongs the Gastric Residence Time of Postprandially Administered Caffeine

(2023) Stefan Senekowitsch et al.   Pharmaceutics

The impact of advanced age on gastrointestinal characteristics that are relevant to oral drug absorption: An AGePOP review

(2023) Cordula Stillhart et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Importance of Gastric Secretion and the Rapid Gastric Emptying of Ingested Water along the Lesser Curvature (“Magenstraße”) in Predicting the In Vivo Performance of Liquid Oral Dosage Forms in the Fed State Using a Modeling and Simulation

(2022) Tsuyoshi Kiyota et al.   MOLECULAR PHARMACEUTICS

Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update

(2022) Astrid Nehlig   Nutrients

Pharmacokinetics of Caffeine: A Systematic Analysis of Reported Data for Application in Metabolic Phenotyping and Liver Function Testing

(2022) Jan Grzegorzewski et al.   Frontiers in Pharmacology

Computational modeling of drug dissolution in the human stomach: Effects of posture and gastroparesis on drug bioavailability

(2022) J. H. Lee et al.   PHYSICS OF FLUIDS

The Effect of Capsule-in-Capsule Combinations on In Vivo Disintegration in Human Volunteers: A Combined Imaging and Salivary Tracer Study

(2021) Adrian Rump et al.   Pharmaceutics

Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review

(2020) Cordula Stillhart et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Advances in the physiology of gastric emptying

(2019) Raj K. Goyal et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Low dose caffeine as a salivary tracer for the determination of gastric water emptying in fed and fasted state: A MRI validation study

(2018) Maximilian Sager et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Interindividual and intraindividual variability of fasted state gastric fluid volume and gastric emptying of water

(2018) Michael Grimm et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The impact of food intake on the luminal environment and performance of oral drug products with a view to in vitro and in silico simulations: a PEARRL review

(2018) Christina Pentafragka et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Effects of Common CYP1A2 Genotypes and Other Key Factors on Intraindividual Variation in the Caffeine Metabolic Ratio: An Exploratory Analysis

(2018) Dan-Dan Tian et al.   CTS-Clinical and Translational Science

The dynamic gastric environment and its impact on drug and formulation behaviour

(2017) Jens Van Den Abeele et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Magnetic Resonance Imaging to Visualize Disintegration of Oral Formulations

(2017) Louise Curley et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Insight Into a Novel Strategy for the Design of Tablet Formulations Intended for Direct Compression

(2017) Maxx Capece et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Gastric Water Emptying under Fed State Clinical Trial Conditions Is as Fast as under Fasted Conditions

(2017) Michael Grimm et al.   MOLECULAR PHARMACEUTICS

Navigating the human gastrointestinal tract for oral drug delivery: Uncharted waters and new frontiers

(2016) Mirko Koziolek et al.   ADVANCED DRUG DELIVERY REVIEWS

Acceptability of oral solid medicines in older adults with and without dysphagia: A nested pilot validation questionnaire based observational study

(2016) Fang Liu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Preference for pharmaceutical formulation and treatment process attributes

(2016) Katie Stewart et al.   Patient Preference and Adherence

Intragastric pH and pressure profiles after intake of the high-caloric, high-fat meal as used for food effect studies

(2015) M. Koziolek et al.   JOURNAL OF CONTROLLED RELEASE

Quantification of Gastrointestinal Liquid Volumes and Distribution Following a 240 mL Dose of Water in the Fasted State

(2014) Deanna M. Mudie et al.   MOLECULAR PHARMACEUTICS

Non-invasive MRI detection of individual pellets in the human stomach

(2009) Manfred Knörgen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Mechanistic understanding of time-dependent oral absorption based on gastric motor activity in humans

(2008) K HIGAKI et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS