Importance of Gastric Secretion and the Rapid Gastric Emptying of Ingested Water along the Lesser Curvature (“Magenstraße”) in Predicting the In Vivo Performance of Liquid Oral Dosage Forms in the Fed State Using a Modeling and Simulation

The Lack of Effect of Food on the Pharmacokinetics of ZX008 (Fenfluramine Oral Solution): Results of a Single-dose, Two-period Crossover Study

(2018) Arnold Gammaitoni et al.   CLINICAL THERAPEUTICS

Predicting the Changes in Oral Absorption of Weak Base Drugs Under Elevated Gastric pH Using an In Vitro–In Silico–In Vivo Approach: Case Examples—Dipyridamole, Prasugrel, and Nelfinavir

(2018) Atsushi Kambayashi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Gastric Water Emptying under Fed State Clinical Trial Conditions Is as Fast as under Fasted Conditions

(2017) Michael Grimm et al.   MOLECULAR PHARMACEUTICS

Prediction of the precipitation profiles of weak base drugs in the small intestine using a simplified transfer (“dumping”) model coupled with in silico modeling and simulation approach

(2016) Atsushi Kambayashi et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Clinical Pharmacokinetic Studies of Enzalutamide

(2015) Jacqueline A. Gibbons et al.   CLINICAL PHARMACOKINETICS

Intragastric pH and pressure profiles after intake of the high-caloric, high-fat meal as used for food effect studies

(2015) M. Koziolek et al.   JOURNAL OF CONTROLLED RELEASE

Prediction of oral absorption of cinnarizine – A highly supersaturating poorly soluble weak base with borderline permeability

(2014) Mark Berlin et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Predicting the oral pharmacokinetic profiles of multiple-unit (pellet) dosage forms using a modeling and simulation approach coupled with biorelevant dissolution testing: Case example diclofenac sodium

(2014) Atsushi Kambayashi et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Intragastric Volume Changes after Intake of a High-Caloric, High-Fat Standard Breakfast in Healthy Human Subjects Investigated by MRI

(2014) Mirko Koziolek et al.   MOLECULAR PHARMACEUTICS

In vitro models for the prediction of in vivo performance of oral dosage forms

(2013) Edmund S. Kostewicz et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Assessment of absorption potential of poorly water-soluble drugs by using the dissolution/permeation system

(2013) Makoto Kataoka et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

An in vitro–in silico–in vivo approach to predicting the oral pharmacokinetic profile of salts of weak acids: Case example dantrolene

(2012) Atsushi Kambayashi et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Precipitation in the small intestine may play a more important role in the in vivo performance of poorly soluble weak bases in the fasted state: Case example nelfinavir

(2011) Yasushi Shono et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Application of Dissolution/Permeation System for Evaluation of Formulation Effect on Oral Absorption of Poorly Water-Soluble Drugs in Drug Development

(2011) Makoto Kataoka et al.   PHARMACEUTICAL RESEARCH

Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans

(2010) Yasushi Shono et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Soft Gelatin Capsules (Softgels)

(2010) Rampurna Prasad Gullapalli   JOURNAL OF PHARMACEUTICAL SCIENCES

Predicting Pharmacokinetics of Drugs Using Physiologically Based Modeling—Application to Food Effects

(2009) N. Parrott et al.   AAPS Journal

Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling

(2009) Yasushi Shono et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Rate-Limiting Steps of Oral Absorption for Poorly Water-Soluble Drugs in Dogs; Prediction from a Miniscale Dissolution Test and a Physiologically-Based Computer Simulation

(2008) Ryusuke Takano et al.   PHARMACEUTICAL RESEARCH