Pharmacokinetics of Caffeine: A Systematic Analysis of Reported Data for Application in Metabolic Phenotyping and Liver Function Testing

2020 FDA Drug-Drug Interaction Guidance -Comparison Analysis and Action Plan by Pharmaceutical Industrial Scientists

(2020) Sirimas Sudsakorn et al.   CURRENT DRUG METABOLISM

Reproducible pharmacokinetics

(2019) John P. A. Ioannidis   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Interindividual Differences in Caffeine Metabolism and Factors Driving Caffeine Consumption

(2018) Astrid Nehlig   PHARMACOLOGICAL REVIEWS

PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation

(2018) Andrea C. Tricco et al.   ANNALS OF INTERNAL MEDICINE

Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes

(2018) Felix Stader et al.   CLINICAL PHARMACOKINETICS

Genotype and Phenotype of Caffeine Metabolism: A Biochemistry Laboratory Experiment

(2018) Julie T. Millard et al.   JOURNAL OF CHEMICAL EDUCATION

Effects of Common CYP1A2 Genotypes and Other Key Factors on Intraindividual Variation in the Caffeine Metabolic Ratio: An Exploratory Analysis

(2018) Dan-Dan Tian et al.   CTS-Clinical and Translational Science

Short-Term Fasting Alters Pharmacokinetics of Cytochrome P450 Probe Drugs: Does Protein Binding Play a Role?

(2017) Laureen A. Lammers et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

The impact of genetic polymorphisms on CYP1A2 activity in humans: a systematic review and meta-analysis

(2017) Nut Koonrungsesomboon et al.   PHARMACOGENOMICS JOURNAL

Establishing population distribution of drug-metabolizing enzyme activities for the use of salivary caffeine as a dynamic liver function marker in a Singaporean Chinese population

(2016) Hazel Yiting Chia et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Heritability of Caffeine Metabolism: Environmental Effects Masking Genetic Effects on CYP1A2 Activity but Not on NAT2

(2016) J Matthaei et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacokinetic analysis and comparison of caffeine administered rapidly or slowly in coffee chilled or hot versus chilled energy drink in healthy young adults

(2016) John R. White et al.   CLINICAL TOXICOLOGY

Assessment of CYP1A2 enzyme activity in relation to type-2 diabetes and habitual caffeine intake

(2016) Emily Urry et al.   Nutrition & Metabolism

Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class

(2016) Julia Dinger et al.   TOXICOLOGY LETTERS

Development and validation of a reversed-phase HPLC method for CYP1A2 phenotyping by use of a caffeine metabolite ratio in saliva

(2015) Elias Begas et al.   BIOMEDICAL CHROMATOGRAPHY

Simultaneous LC-MS/MS Analysis of the Plasma Concentrations of a Cocktail of 5 Cytochrome P450 Substrate Drugs and Their Metabolites

(2014) Shimako Tanaka et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Beverage caffeine intakes in the U.S.

(2013) Diane C. Mitchell et al.   FOOD AND CHEMICAL TOXICOLOGY

The effect of single- and multiple-dose etravirine on a drug cocktail of representative cytochrome P450 probes and digoxin in healthy subjects

(2013) Thomas N. Kakuda et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

Monitoring Caffeine in Human Saliva Using a Newly Developed ELISA

(2012) José João Carvalho et al.   ANALYTICAL LETTERS

Changes in CYP1A2 Activity in Humans after 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy) Administration Using Caffeine as a Probe Drug

(2012) Samanta Yubero-Lahoz et al.   Drug Metabolism and Pharmacokinetics

High-sensitivity liquid chromatography–tandem mass spectrometry for the simultaneous determination of five drugs and their cytochrome P450-specific probe metabolites in human plasma

(2012) Kyung-Suk Oh et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Pharmacokinetics of caffeine in plasma and saliva, and the influence of caffeine abstinence on CYP1A2 metrics

(2011) Vidya Perera et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Plant Polyphenol Curcumin Significantly Affects CYP1A2 and CYP2A6 Activity in Healthy, Male Chinese Volunteers

(2010) Y. Chen et al.   ANNALS OF PHARMACOTHERAPY

Caffeine and paraxanthine HPLC assay for CYP1A2 phenotype assessment using saliva and plasma

(2010) Vidya Perera et al.   BIOMEDICAL CHROMATOGRAPHY

A Phenotype–Genotype Approach to Predicting CYP450 and P-Glycoprotein Drug Interactions With the Mixed Inhibitor/Inducer Tipranavir/Ritonavir

(2010) J B Dumond et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

(2010) X. Yang et al.   GENOME RESEARCH

Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver

(2010) Kathrin Klein et al.   Frontiers in Pharmacology

Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A

(2009) Sandrine Turpault et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

SIMULTANEOUS ACTION OF THE FLAVONOID QUERCETIN ON CYTOCHROME P450 (CYP) 1A2, CYP2A6,N-ACETYLTRANSFERASE AND XANTHINE OXIDASE ACTIVITY IN HEALTHY VOLUNTEERS

(2009) Yao Chen et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Interaction Profile of Armodafinil with Medications Metabolized by Cytochrome P450 Enzymes 1A2, 3A4 and 2C19 in Healthy Subjects

(2009) Mona Darwish et al.   CLINICAL PHARMACOKINETICS

Caffeine Metabolic Ratios for the In Vivo Evaluation of CYP1A2, N-acetyltransferase 2, Xanthine Oxidase and CYP2A6 Enzymatic Activities

(2009) Nancy Hakooz   CURRENT DRUG METABOLISM

Influence of genetic polymorphisms, smoking, gender and age on CYP1A2 activity in a Turkish population

(2009) Arzu Gunes et al.   PHARMACOGENOMICS

A High-Throughput Assay Using Liquid Chromatography-Tandem Mass Spectrometry for Simultaneous In Vivo Phenotyping of 5 Major Cytochrome P450 Enzymes in Patients

(2009) Sussan Ghassabian et al.   THERAPEUTIC DRUG MONITORING

Effect of sodium tanshinone II A sulfonate on the activity of CYP1A2 in healthy volunteers

(2009) Y. Chen et al.   XENOBIOTICA

Comparison of CYP1A2 and NAT2 phenotypes between black and white smokers

(2008) Joshua E. Muscat et al.   BIOCHEMICAL PHARMACOLOGY

Pharmacokinetics/Genotype Associations for Major Cytochrome P450 Enzymes in Native and First- and Third-generation Japanese Populations: Comparison With Korean, Chinese, and Caucasian Populations

(2008) SP Myrand et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Population pharmacokinetics of caffeine in healthy male adults using mixed-effects models

(2008) K.-Y. Seng et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Variation in CYP1A2 activity and its clinical implications: influence of environmental factors and genetic polymorphisms

(2008) Arzu Gunes et al.   PHARMACOGENOMICS