Capturing a substrate in an activated RING E3/E2–SUMO complex

Activation of a Primed RING E3-E2–Ubiquitin Complex by Non-Covalent Ubiquitin

(2015) Lori Buetow et al.   MOLECULAR CELL

Atomic structure of the APC/C and its mechanism of protein ubiquitination

(2015) Leifu Chang et al.   NATURE

Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity

(2015) Joshua D Wright et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase

(2015) Laurent Cappadocia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity

(2015) Joshua D Wright et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase

(2015) Laurent Cappadocia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural and Functional Insights to Ubiquitin-Like Protein Conjugation

(2014) Frederick C. Streich et al.   Annual Review of Biophysics

Structure of a RING E3 Trapped in Action Reveals Ligation Mechanism for the Ubiquitin-like Protein NEDD8

(2014) Daniel C. Scott et al.   CELL

Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome

(2014) Robert K. McGinty et al.   NATURE

Control of Nuclear Activities by Substrate-Selective and Protein-Group SUMOylation

(2013) Stefan Jentsch et al.   Annual Review of Genetics

Identification of a Non-covalent Ternary Complex Formed by PIAS1, SUMO1, and UBC9 Proteins Involved in Transcriptional Regulation

(2013) Xavier H. Mascle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3

(2013) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Insights into the Conformation and Oligomerization of E2∼Ubiquitin Conjugates

(2012) Richard C. Page et al.   BIOCHEMISTRY

Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

(2012) Jonathan N. Pruneda et al.   MOLECULAR CELL

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

(2012) Anna Plechanovová et al.   NATURE

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2

(2012) Anthony A. Armstrong et al.   NATURE

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

(2012) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA

(2012) Joanne L. Parker et al.   NUCLEIC ACIDS RESEARCH

The Mechanism of Linkage-Specific Ubiquitin Chain Elongation by a Single-Subunit E2

(2011) Katherine E. Wickliffe et al.   CELL

Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A

(2011) Ivan Bosanac et al.   JOURNAL OF MOLECULAR BIOLOGY

Essential Role for Ubiquitin-Ubiquitin-Conjugating Enzyme Interaction in Ubiquitin Discharge from Cdc34 to Substrate

(2011) Anjanabha Saha et al.   MOLECULAR CELL

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Catalysis of Lysine 48-Specific Ubiquitin Chain Assembly by Residues in E2 and Ubiquitin

(2010) Monica C. Rodrigo-Brenni et al.   MOLECULAR CELL

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

PIAS proteins: pleiotropic interactors associated with SUMO

(2009) Miia M. Rytinki et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanistic analysis of PCNA poly-ubiquitylation by the ubiquitin protein ligases Rad18 and Rad5

(2009) Joanne L Parker et al.   EMBO JOURNAL

Phospho-Regulated SUMO Interaction Modules Connect the SUMO System to CK2 Signaling

(2009) Per Stehmeier et al.   MOLECULAR CELL

Structure of the Siz/PIAS SUMO E3 Ligase Siz1 and Determinants Required for SUMO Modification of PCNA

(2009) Ali A. Yunus et al.   MOLECULAR CELL

Origin and function of ubiquitin-like proteins

(2009) Mark Hochstrasser   NATURE

SUMO modification of PCNA is controlled by DNA

(2008) Joanne L Parker et al.   EMBO JOURNAL

Ubc9 Sumoylation Regulates SUMO Target Discrimination

(2008) Puck Knipscheer et al.   MOLECULAR CELL