Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity

Zebrafish Rnf111 is encoded by multiple transcripts and is required for epiboly progression and prechordal plate development

(2015) Dmitri A. Bessarab et al.   DIFFERENTIATION

RNF111/Arkadia is regulated by DNA methylation and affects TGF-β/Smad signaling associated invasion in NSCLC cells

(2015) Hongbing Chen et al.   LUNG CANCER

SEDPHAT – A platform for global ITC analysis and global multi-method analysis of molecular interactions

(2015) Huaying Zhao et al.   METHODS

Activation of a Primed RING E3-E2–Ubiquitin Complex by Non-Covalent Ubiquitin

(2015) Lori Buetow et al.   MOLECULAR CELL

Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains

(2015) Emma Branigan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Specificity of the anaphase-promoting complex: A single-molecule study

(2015) Y. Lu et al.   SCIENCE

SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair

(2015) Loes van Cuijk et al.   Nature Communications

Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains

(2015) Emma Branigan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multiple Arkadia/RNF111 Structures Coordinate Its Polycomb Body Association and Transcriptional Control

(2014) Huaiyu Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

Ubiquitin Chain Elongation Requires E3-Dependent Tracking of the Emerging Conjugate

(2014) Aileen Kelly et al.   MOLECULAR CELL

Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly

(2014) Nicholas G. Brown et al.   MOLECULAR CELL

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal

(2014) Paul A. DaRosa et al.   NATURE

Ubiquitin-binding domains: Mechanisms of ubiquitin recognition and use as tools to investigate ubiquitin-modified proteomes

(2014) Daniel Scott et al.   PROTEOMICS

ThePDB_REDOserver for macromolecular structure model optimization

(2014) Robbie P. Joosten et al.   IUCrJ

Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase

(2013) Yoshio Nakatani et al.   BIOCHEMICAL JOURNAL

RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination

(2013) Meredith B. Metzger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Arkadia Regulates Tumor Metastasis by Modulation of the TGF-  Pathway

(2013) M. A. Briones-Orta et al.   CANCER RESEARCH

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

(2013) Sara L. Poulsen et al.   JOURNAL OF CELL BIOLOGY

Arkadia, a Novel SUMO-Targeted Ubiquitin Ligase Involved in PML Degradation

(2013) Y. Erker et al.   MOLECULAR AND CELLULAR BIOLOGY

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3

(2013) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Assembly, analysis and architecture of atypical ubiquitin chains

(2013) Manuela K Hospenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rnf165/Ark2C Enhances BMP-Smad Signaling to Mediate Motor Axon Extension

(2013) Claire E. Kelly et al.   PLOS BIOLOGY

High-Precision Isothermal Titration Calorimetry with Automated Peak-Shape Analysis

(2012) Sandro Keller et al.   ANALYTICAL CHEMISTRY

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Poly-Small Ubiquitin-like Modifier (PolySUMO)-binding Proteins Identified through a String Search

(2012) Huaiyu Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

(2012) Jonathan N. Pruneda et al.   MOLECULAR CELL

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

(2012) Anna Plechanovová et al.   NATURE

Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

(2012) Yogesh Kulathu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

(2012) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl

(2012) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NMR-based insights into the conformational and interaction properties of Arkadia RING-H2 E3 Ub ligase

(2012) Christos T. Chasapis et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Enhancement of TGF-  Signaling Responses by the E3 Ubiquitin Ligase Arkadia Provides Tumor Suppression in Colorectal Cancer

(2011) V. Sharma et al.   CANCER RESEARCH

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

(2011) Dawn M. Wenzel et al.   NATURE

Protein standard absolute quantification (PSAQ) method for the measurement of cellular ubiquitin pools

(2011) Stephen E Kaiser et al.   NATURE METHODS

The spatial and temporal organization of ubiquitin networks

(2011) Caroline Grabbe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RINGs hold the key to ubiquitin transfer

(2011) Rhesa Budhidarmo et al.   TRENDS IN BIOCHEMICAL SCIENCES

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling

(2010) Ivan Bosanac et al.   MOLECULAR CELL

Crystal Structure of UbcH5b∼Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2∼Ub Conjugates

(2010) Eri Sakata et al.   STRUCTURE

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment

(2008) Peter D. Mace et al.   JOURNAL OF BIOLOGICAL CHEMISTRY