Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells
Authors
Keywords
-
Journal
NATURE
Volume 534, Issue 7607, Pages 341-346
Publisher
Springer Nature
Online
2016-06-07
DOI
10.1038/nature18288
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials
- (2016) Brian K. Albrecht et al. JOURNAL OF MEDICINAL CHEMISTRY
- Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists
- (2015) Stéphane Prost et al. NATURE
- The spliceosome is a therapeutic vulnerability in MYC-driven cancer
- (2015) Tiffany Y.-T. Hsu et al. NATURE
- MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis
- (2015) Cheryl M. Koh et al. NATURE
- BET inhibitor resistance emerges from leukaemia stem cells
- (2015) Chun Yew Fong et al. NATURE
- A Panel of Regulated Proteins in Serum from Patients with Cervical Intraepithelial Neoplasia and Cervical Cancer
- (2014) Alexander P. Boichenko et al. JOURNAL OF PROTEOME RESEARCH
- Glycoproteomic Analysis of Prostate Cancer Tissues by SWATH Mass Spectrometry Discovers N-acylethanolamine Acid Amidase and Protein Tyrosine Kinase 7 as Signatures for Tumor Aggressiveness
- (2014) Yansheng Liu et al. MOLECULAR & CELLULAR PROTEOMICS
- Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers
- (2014) A Sheth et al. Cell Death & Disease
- The bromodomain and extra-terminal inhibitor CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors
- (2014) C Wong et al. Cell Death & Disease
- voom: precision weights unlock linear model analysis tools for RNA-seq read counts
- (2014) Charity W Law et al. GENOME BIOLOGY
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile
- (2013) K. Cramer-Morales et al. BLOOD
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- Regulation of c-Myc Ubiquitination Controls Chronic Myelogenous Leukemia Initiation and Progression
- (2013) Linsey Reavie et al. CANCER CELL
- Ablation of Fbxw7 Eliminates Leukemia-Initiating Cells by Preventing Quiescence
- (2013) Shoichiro Takeishi et al. CANCER CELL
- MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models
- (2013) C. Tovar et al. CANCER RESEARCH
- PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells
- (2013) Paolo Neviani et al. JOURNAL OF CLINICAL INVESTIGATION
- The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote
- (2013) Yang Liao et al. NUCLEIC ACIDS RESEARCH
- Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib
- (2012) Ling Li et al. CANCER CELL
- Scd1 Plays a Tumor-Suppressive Role in Survival of Leukemia Stem Cells and the Development of Chronic Myeloid Leukemia
- (2012) H. Zhang et al. MOLECULAR AND CELLULAR BIOLOGY
- Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML
- (2012) Georg E Winter et al. Nature Chemical Biology
- MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27KIP1
- (2012) M T Gómez-Casares et al. ONCOGENE
- Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
- (2011) A. Hamilton et al. BLOOD
- BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia
- (2011) Christian Hurtz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Targeting MYC dependence in cancer by inhibiting BET bromodomains
- (2011) J. A. Mertz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene Expression Differences between Enriched Normal and Chronic Myelogenous Leukemia Quiescent Stem/Progenitor Cells and Correlations with Biological Abnormalities
- (2011) M. Affer et al. Journal of Oncology
- Effective Targeting of Quiescent Chronic Myelogenous Leukemia Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate
- (2010) Bin Zhang et al. CANCER CELL
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity
- (2010) Amie S. Corbin et al. JOURNAL OF CLINICAL INVESTIGATION
- Quantitative Proteomic Profiling of Matched Normal and Tumor Breast Tissues
- (2010) Chris W. Sutton et al. JOURNAL OF PROTEOME RESEARCH
- Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial
- (2010) François-Xavier Mahon et al. LANCET ONCOLOGY
- MYC regulation of a “poor-prognosis” metastatic cancer cell state
- (2010) Anita Wolfer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A scaling normalization method for differential expression analysis of RNA-seq data
- (2010) Mark D Robinson et al. GENOME BIOLOGY
- A gene expression signature of CD34+ cells to predict major cytogenetic response in chronic-phase chronic myeloid leukemia patients treated with imatinib
- (2009) S. K. McWeeney et al. BLOOD
- Retinoblastoma Has Properties of a Cone Precursor Tumor and Depends Upon Cone-Specific MDM2 Signaling
- (2009) Xiaoliang L. Xu et al. CELL
- Blinded by the Light: The Growing Complexity of p53
- (2009) Karen H. Vousden et al. CELL
- Transient Potent BCR-ABL Inhibition Is Sufficient to Commit Chronic Myeloid Leukemia Cells Irreversibly to Apoptosis
- (2008) Neil P. Shah et al. CANCER CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search