Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers

A Mitochondrial Ribosomal and RNA Decay Pathway Blocks Cell Proliferation

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Transcriptional regulation of the human mitochondrial peptide deformylase (PDF)

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New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity

(2012) Emilie Goemaere et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Peptidomimetic inhibitors of bacterial peptide deformylase

(2011) Stephen P. East et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Mutations in MTFMT Underlie a Human Disorder of Formylation Causing Impaired Mitochondrial Translation

(2011) Elena J. Tucker et al.   Cell Metabolism

Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells

(2011) Markus D. Siegelin et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of Human Peptide Deformylase Disrupts Mitochondrial Function

(2010) S. Escobar-Alvarez et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptional Control of Mitochondrial Biogenesis and Function

(2009) M. Benjamin Hock et al.   Annual Review of Physiology

Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation

(2009) Melanie A. Berta et al.   EMBO Molecular Medicine

Peptide deformylase – a promising therapeutic target for tuberculosis and antibacterial drug discovery

(2009) Anshika Sharma et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Structure and Activity of Human Mitochondrial Peptide Deformylase, a Novel Cancer Target

(2009) Sindy Escobar-Alvarez et al.   JOURNAL OF MOLECULAR BIOLOGY

Modelling Myc inhibition as a cancer therapy

(2008) Laura Soucek et al.   NATURE

Global Identification of Myc Target Genes Reveals Its Direct Role in Mitochondrial Biogenesis and Its E-Box Usage In Vivo

(2008) Jonghwan Kim et al.   PLoS One