Human Mesenchymal Stem Cells-Derived Exosome Mimetic Vesicles Regulation of the MAPK Pathway and ROS Levels Inhibits Glucocorticoid-Induced Apoptosis in Osteoblasts

Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head

(2022) Fei Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Comprehensive proteomic analysis of exosome mimetic vesicles and exosomes derived from human umbilical cord mesenchymal stem cells

(2022) Zhaoxia Zhang et al.   Stem Cell Research & Therapy

Exosome mimetics derived from bone marrow mesenchymal stem cells deliver doxorubicin to osteosarcoma in vitro and in vivo

(2022) Jinkui Wang et al.   DRUG DELIVERY

Mitophagy and apoptosis mediated by ROS participate in AlCl3-induced MC3T3-E1 cell dysfunction

(2021) Menglin Liu et al.   FOOD AND CHEMICAL TOXICOLOGY

Polystyrene microplastics disrupt the blood-testis barrier integrity through ROS-Mediated imbalance of mTORC1 and mTORC2

(2021) Yuexin Wei et al.   ENVIRONMENTAL POLLUTION

Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways

(2021) Baocheng Xie et al.   Frontiers in Pharmacology

Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo

(2020) Jiangjiang Fan et al.   Cell Death & Disease

Understanding MAPK Signaling Pathways in Apoptosis

(2020) Jicheng Yue et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanovesicles derived from iron oxide nanoparticles–incorporated mesenchymal stem cells for cardiac repair

(2020) Ju-Ro Lee et al.   Science Advances

Targeted Delivery of Mesenchymal Stem Cell-Derived Nanovesicles for Spinal Cord Injury Treatment

(2020) Ju-Ro Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Generation of Small RNA-Modulated Exosome Mimetics for Bone Regeneration

(2020) Jiabing Fan et al.   ACS Nano

Multiple transcriptomic profiling: p53 signaling pathway is involved in DEHP-induced prepubertal testicular injury via promoting cell apoptosis and inhibiting cell proliferation of Leydig cells

(2020) Junke Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy

(2019) Keywan Mortezaee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular carcinoma

(2019) Guangya Zhang et al.   Cell Death & Disease

NADPH Oxidase Isoforms Are Involved in Glucocorticoid-Induced Preosteoblast Apoptosis

(2019) Shu-Cai Bai et al.   Oxidative Medicine and Cellular Longevity

BMSC-derived exosomes carrying microRNA-122-5p promote proliferation of osteoblasts in osteonecrosis of the femoral head

(2019) Wen Liao et al.   CLINICAL SCIENCE

Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer

(2019) Yannan Liu et al.   BIOCHEMICAL PHARMACOLOGY

Mesenchymal Stromal Cell-Based Bone Regeneration Therapies: From Cell Transplantation and Tissue Engineering to Therapeutic Secretomes and Extracellular Vesicles

(2019) Darja Marolt Presen et al.   Frontiers in Bioengineering and Biotechnology

Therapeutic Efficacy-Potentiated and Diseased Organ-Targeting Nanovesicles Derived from Mesenchymal Stem Cells for Spinal Cord Injury Treatment

(2018) Han Young Kim et al.   NANO LETTERS

A New Approach for Loading Anticancer Drugs Into Mesenchymal Stem Cell-Derived Exosome Mimetics for Cancer Therapy

(2018) Senthilkumar Kalimuthu et al.   Frontiers in Pharmacology

Stem cell therapy for treating osteonecrosis of the femoral head: From clinical applications to related basic research

(2018) Rui Li et al.   Stem Cell Research & Therapy

Dexamethasone induces osteoblast apoptosis through ROS-PI3K/AKT/GSK3β signaling pathway

(2018) Shuang Deng et al.   BIOMEDICINE & PHARMACOTHERAPY

Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis

(2017) Xiaolin Liu et al.   International Journal of Biological Sciences

Bone mesenchymal stem cells co‑expressing VEGF and BMP‑6 genes to combat avascular necrosis of the femoral head

(2017) Hongxing Liao et al.   Experimental and Therapeutic Medicine

Preclinical Study of Cell Therapy for Osteonecrosis of the Femoral Head with Allogenic Peripheral Blood-Derived Mesenchymal Stem Cells

(2016) Qiang Fu et al.   YONSEI MEDICAL JOURNAL

Dexamethasone-induced apoptosis of osteocytic and osteoblastic cells is mediated by TAK1 activation

(2015) Heyuan Ding et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prevention of glucocorticoid induced-apoptosis of osteoblasts and osteocytes by protecting against endoplasmic reticulum (ER) stress in vitro and in vivo in female mice

(2015) Amy Y. Sato et al.   BONE

Nontraumatic Osteonecrosis of the Femoral Head: Where Do We Stand Today?

(2015) Michael A Mont et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Biomarkers and pharmaceutical strategies in steroid-induced osteonecrosis of the femoral head: A literature review

(2014) Xinyu Qi et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

The etiology of oxidative stress in the various species of animals, a review

(2014) Kamila Puppel et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Epidemiology of nontraumatic osteonecrosis of the femoral head in Japan

(2014) Kazuma Ikeuchi et al.   Modern Rheumatology

Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors

(2013) Su Chul Jang et al.   ACS Nano

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

(2013) Krishnendu Sinha et al.   ARCHIVES OF TOXICOLOGY

The role of nacreous factors in preventing osteoporotic bone loss through both osteoblast activation and osteoclast inactivation

(2012) Hyunsoo Kim et al.   BIOMATERIALS

Sesamin stimulates osteoblast differentiation through p38 and ERK1/2 MAPK signaling pathways

(2012) Orawan Wanachewin et al.   BMC Complementary and Alternative Medicine

Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells

(2011) Dewei Zhao et al.   BONE

The effect of dexamethasone and hypoxic stress on MC3T3-E1 cells

(2011) Zhen-Hong Zhu   Frontiers in Bioscience-Landmark

Oxidative stress in bone remodelling and disease

(2009) Fabien Wauquier et al.   TRENDS IN MOLECULAR MEDICINE