Stem cell therapy for treating osteonecrosis of the femoral head: From clinical applications to related basic research

Stem Cells Combined With Platelet-rich Plasma Effectively Treat Corticosteroid-induced Osteonecrosis of the Hip

(2018) Matthew T. Houdek et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis

(2017) Xiaolin Liu et al.   International Journal of Biological Sciences

Concise Review: MSC-Derived Exosomes for Cell-Free Therapy

(2017) Donald G. Phinney et al.   STEM CELLS

Aldehyde dehydrogenase activity helps identify a subpopulation of murine adipose-derived stem cells with enhanced adipogenic and osteogenic differentiation potential

(2017) Harumichi Itoh et al.   World Journal of Stem Cells

Treatment of Femoral Head Necrosis With Bone Marrow Mesenchymal Stem Cells Expressing Inducible Hepatocyte Growth Factor

(2016) Zhi-Min Pan et al.   AMERICAN JOURNAL OF THERAPEUTICS

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Effects of hypoxia on osteogenic differentiation of mesenchymal stromal cells used as a cell therapy for avascular necrosis of the femoral head

(2016) Gabriela Ciapetti et al.   CYTOTHERAPY

The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration

(2016) Vijay Bhaskar Reddy Konala et al.   CYTOTHERAPY

The safety and efficacy of combined autologous concentrated bone marrow grafting and low-intensity pulsed ultrasound in the treatment of osteonecrosis of the femoral head

(2016) Hajime Mishima et al.   European Journal of Orthopaedic Surgery and Traumatology

Exosomes from Human Synovial-Derived Mesenchymal Stem Cells Prevent Glucocorticoid-Induced Osteonecrosis of the Femoral Head in the Rat

(2016) Shang-Chun Guo et al.   International Journal of Biological Sciences

Decreased Osteogenic Activity of Mesenchymal Stem Cells in Patients With Corticosteroid-Induced Osteonecrosis of the Femoral Head

(2016) Matthew T. Houdek et al.   JOURNAL OF ARTHROPLASTY

Efficacy of umbilical cord-derived mesenchymal stem cell-based therapy for osteonecrosis of the femoral head: A three-year follow-up study

(2016) Chun Chen et al.   Molecular Medicine Reports

Mesenchymal Stem Cells Subpopulations: Application for Orthopedic Regenerative Medicine

(2016) Vanessa Pérez-Silos et al.   Stem Cells International

The role of “cell therapy” in osteonecrosis of the femoral head

(2015) Costas Papakostidis et al.   Acta Orthopaedica

Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and osteogenesis in rabbit femoral head osteonecrosis

(2015) Lihong Fan et al.   BONE

Prevalence of Nontraumatic Osteonecrosis of the Femoral Head and its Associated Risk Factors in the Chinese Population: Results from a Nationally Representative Survey

(2015) De-Wei Zhao et al.   CHINESE MEDICAL JOURNAL

Adipose-derived Mesenchymal Stem Cells Are Phenotypically Superior for Regeneration in the Setting of Osteonecrosis of the Femoral Head

(2015) Cody C. Wyles et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Combining Concentrated Autologous Bone Marrow Stem Cells Injection With Core Decompression Improves Outcome for Patients with Early-Stage Osteonecrosis of the Femoral Head: A Comparative Study

(2015) Reza Mostafavi Tabatabaee et al.   JOURNAL OF ARTHROPLASTY

Nontraumatic Osteonecrosis of the Femoral Head: Where Do We Stand Today?

(2015) Michael A Mont et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Combination Treatment of Biomechanical Support and Targeted Intra-arterial Infusion of Peripheral Blood Stem Cells Mobilized by Granulocyte-Colony Stimulating Factor for the Osteonecrosis of the Femoral Head: A Randomized Controlled Clinical Trial

(2015) Qiang Mao et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Prolonged Exposure to Hypoxic Milieu Improves the Osteogenic Potential of Adipose Derived Stem Cells

(2015) Caterina Fotia et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Differential Expression of Adhesion-Related Proteins and MAPK Pathways Lead to Suitable Osteoblast Differentiation of Human Mesenchymal Stem Cells Subpopulations

(2015) Margarita Leyva-Leyva et al.   STEM CELLS AND DEVELOPMENT

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Donor age negatively impacts adipose tissue-derived mesenchymal stem cell expansion and differentiation

(2014) Mahmood S Choudhery et al.   Journal of Translational Medicine

Continuous hypoxia regulates the osteogenic potential of mesenchymal stem cells in a time-dependent manner

(2014) HAO DING et al.   Molecular Medicine Reports

An Exploratory Clinical Trial for Idiopathic Osteonecrosis of Femoral Head by Cultured Autologous Multipotent Mesenchymal Stromal Cells Augmented with Vascularized Bone Grafts

(2014) Tomoki Aoyama et al.   TISSUE ENGINEERING PART B-REVIEWS

Cotransplantation of Bone Marrow Mononuclear Cells and Umbilical Cord Mesenchymal Stem Cells in Avascular Necrosis of the Femoral Head

(2014) J. Cai et al.   TRANSPLANTATION PROCEEDINGS

Efficacy of autologous bone marrow buffy coat grafting combined with core decompression in patients with avascular necrosis of femoral head: a prospective, double-blinded, randomized, controlled study

(2014) Yuanchen Ma et al.   Stem Cell Research & Therapy

Osteogenic Potential of Mouse Adipose-Derived Stem Cells Sorted for CD90 and CD105 In Vitro

(2014) Maiko Yamamoto et al.   Stem Cells International

A tissue engineering strategy for the treatment of avascular necrosis of the femoral head

(2013) A. Aarvold et al.   SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND

Clinical Results of Auto-Iliac Cancellous Bone Grafts Combined with Implantation of Autologous Bone Marrow Cells for Osteonecrosis of the Femoral Head: A Minimum 5-Year Follow-Up

(2013) Joon Soon Kang et al.   YONSEI MEDICAL JOURNAL

From bench to clinic and back: skeletal stem cells and impaction bone grafting for regeneration of bone defects

(2012) A. Aarvold et al.   Journal of Tissue Engineering and Regenerative Medicine

Characterization of Mesenchymal Stem Cell Subpopulations from Human Amniotic Membrane with Dissimilar Osteoblastic Potential

(2012) Margarita Leyva-Leyva et al.   STEM CELLS AND DEVELOPMENT

Safety of Mesenchymal Stem Cells for Clinical Application

(2012) Youwei Wang et al.   Stem Cells International

Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases?

(2012) Shayne A. Bellingham et al.   Frontiers in Physiology

Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: Five year follow-up of a prospective controlled study

(2011) Valérie Gangji et al.   BONE

Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells

(2011) Dewei Zhao et al.   BONE

Treatment of Osteonecrosis of the Femoral Head with VEGF165Transgenic Bone Marrow Mesenchymal Stem Cells in Mongrel Dogs

(2011) Donghua Hang et al.   CELLS TISSUES ORGANS

Early Results of Core Decompression and Autologous Bone Marrow Mononuclear Cells Instillation in Femoral Head Osteonecrosis

(2011) Ramesh Kumar Sen et al.   JOURNAL OF ARTHROPLASTY

CD105 Protein Depletion Enhances Human Adipose-derived Stromal Cell Osteogenesis through Reduction of Transforming Growth Factor β1 (TGF-β1) Signaling

(2011) Benjamin Levi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia promotes proliferation and osteogenic differentiation potentials of human mesenchymal stem cells

(2011) Shun-Pei Hung et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Bone-marrow-derived mononuclear cells with a porous hydroxyapatite scaffold for the treatment of osteonecrosis of the femoral head

(2010) T. Yamasaki et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

Distinct Stem Cells Subpopulations Isolated from Human Adipose Tissue Exhibit Different Chondrogenic and Osteogenic Differentiation Potential

(2010) Tommaso Rada et al.   Stem Cell Reviews and Reports

Cell therapy of hip osteonecrosis with autologous bone marrow grafting

(2009) Philippe Hernigou et al.   Indian Journal of Orthopaedics

Role of Gender and Anatomical Region on Induction of Osteogenic Differentiation of Human Adipose-derived Stem Cells

(2008) A Emre Aksu et al.   ANNALS OF PLASTIC SURGERY

Adventage of mesenchymal stem cells (MSC) expansion directly from purified bone marrow CD105+ and CD271+ cells.

(2008) Danuta Jarocha et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Treatment of avascular necrosis of the femoral head by hepatocyte growth factor-transgenic bone marrow stromal stem cells

(2008) Q Wen et al.   GENE THERAPY

Fate of mesenchymal stem cells transplanted to osteonecrosis of femoral head

(2008) Zuoqin Yan et al.   JOURNAL OF ORTHOPAEDIC RESEARCH