Exogenous H2S promotes ubiquitin‐mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S‐sulfhydration

Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration

(2023) Shanshan Luo et al.   CIRCULATION

Protein S-sulfhydration: Unraveling the prospective of hydrogen sulfide in the brain, vasculature and neurological manifestations

(2022) Rohan Gupta et al.   AGEING RESEARCH REVIEWS

Mitochondrial H 2 S Regulates BCAA Catabolism in Heart Failure

(2022) Zhen Li et al.   CIRCULATION RESEARCH

PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis

(2022) Ju Youn Kim et al.   Cell Metabolism

Sphingomyelin phosphodiesterase acid like 3B (SMPDL3b) regulates Perilipin5 (PLIN5) expression and mediates lipid droplet formation

(2022) Shamroop Kumar Mallela et al.   Genes and Diseases

SREBP-1c and lipogenesis in the liver: an update

(2021) Pascal Ferré et al.   BIOCHEMICAL JOURNAL

Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S‐sulfhydration

(2021) Yu Sun et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Endoplasmic reticulum-associated degradation and beyond: The multitasking roles for HRD1 in immune regulation and autoimmunity

(2020) Yuanming Xu et al.   JOURNAL OF AUTOIMMUNITY

Basic Mechanisms of Diabetic Heart Disease

(2020) Rebecca H. Ritchie et al.   CIRCULATION RESEARCH

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis

(2020) Daqian Xu et al.   NATURE

Endoplasmic reticulum–associated degradation regulates mitochondrial dynamics in brown adipocytes

(2020) Zhangsen Zhou et al.   SCIENCE

Mapping the Endothelial Cell S -Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function

(2020) Sofia-Iris Bibli et al.   CIRCULATION

Cardiomyopathy in obesity, insulin resistance or diabetes

(2019) Michinari Nakamura et al.   JOURNAL OF PHYSIOLOGY-LONDON

S-1-propenylmercaptocysteine protects murine hepatocytes against oxidative stress via persulfidation of Keap1 and activation of Nrf2

(2019) Restituto Tocmo et al.   FREE RADICAL BIOLOGY AND MEDICINE

IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045

(2018) N.H. Cho et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P

(2018) Ju Youn Kim et al.   CELL

SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology

(2017) Hitoshi Shimano et al.   Nature Reviews Endocrinology

International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H 2 S Levels: H 2 S Donors and H 2 S Biosynthesis Inhibitors

(2017) Csaba Szabo et al.   PHARMACOLOGICAL REVIEWS

Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy

(2017) Jichao Wu et al.   Cell Death & Disease

An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network

(2017) Yang Li et al.   Nature Communications

H2S-Induced Sulfhydration: Biological Function and Detection Methodology

(2017) Da Zhang et al.   Frontiers in Pharmacology

Delayed gastric emptying in diabetic rats caused by decreased expression of cystathionine gamma lyase and H2S synthesis:in vitroandin vivostudies

(2016) S. A. Mard et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The Role of Endoplasmic Reticulum Stress in Human Pathology

(2015) Scott A. Oakes et al.   Annual Review of Pathology-Mechanisms of Disease

The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1

(2015) Jinbo Han et al.   NATURE

Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy

(2015) Guanghong Jia et al.   Nature Reviews Endocrinology

Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis

(2013) X Yuan et al.   ONCOGENE

Yeast SREBP Cleavage Activation Requires the Golgi Dsc E3 Ligase Complex

(2011) Emerson V. Stewart et al.   MOLECULAR CELL

Degradation of Sterol Regulatory Element-binding Protein Precursor Requires the Endoplasmic Reticulum-associated Degradation Components Ubc7 and Hrd1 in Fission Yeast

(2009) Bridget T. Hughes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY